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1E0F

Crystal structure of the human alpha-thrombin-haemadin complex: an exosite II-binding inhibitor

Summary for 1E0F
Entry DOI10.2210/pdb1e0f/pdb
Related1A2C 1A3B 1A3E 1A46 1A4W 1A5G 1A61 1ABI 1ABJ 1AD8 1AFE 1AHT 1AI8 1AIX 1AWF 1AWH 1AY6 1B5G 1B7X 1BA8 1BBO 1BHX 1BMM 1BMN 1BTH 1DIT 1DWB 1DWC 1DWD 1DWE 1FPC 1HAG 1HAH 1HAI 1HAO 1HAP 1HBT 1HDT 1HGT 1HLT 1HUT 1HXE 1HXF 1IHS 1IHT 1LHC 1LHD 1LHE 1LHF 1LHG 1NRN 1NRO 1NRP 1NRQ 1NRR 1NRS 1PPB 1TBZ 1THP 1THR 1THS 1TMB 1TMT 1TMU 1TOM 1UMA 1UVS 1UVT 1UVU 1VR1 2HGT 2HNT 2THF 3HAT 3HTC 4HTC 7KME 8KME
DescriptorTHROMBIN, HAEMADIN, ... (4 entities in total)
Functional Keywordscoagulation/crystal structure/heparin-b, coagulation/crystal structure/heparin-binding site/ hirudin/thrombin inhibitor, hydrolase
Biological sourceHAEMADIPSA SYLVESTRIS
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Total number of polymer chains9
Total formula weight120454.98
Authors
Richardson, J.L.,Kroeger, B.,Hoefken, W.,Pereira, P.,Huber, R.,Bode, W.,Fuentes-Prior, P. (deposition date: 2000-03-27, release date: 2000-11-03, Last modification date: 2023-12-06)
Primary citationRichardson, J.L.,Kroeger, B.,Hoeffken, W.,Sadler, J.E.,Pereira, P.,Huber, R.,Bode, W.,Fuentes-Prior, P.
Crystal Structure of the Human Alpha-Thrombin-Haemadin Complex: An Exosite II-Binding Inhibitor
Embo J., 19:5650-, 2000
Cited by
PubMed: 11060016
DOI: 10.1093/EMBOJ/19.21.5650
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (3.1 Å)
Structure validation

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