3HTC
THE STRUCTURE OF A COMPLEX OF RECOMBINANT HIRUDIN AND HUMAN ALPHA-THROMBIN
Summary for 3HTC
Entry DOI | 10.2210/pdb3htc/pdb |
Descriptor | ALPHA-THROMBIN (SMALL SUBUNIT), ALPHA-THROMBIN (LARGE SUBUNIT), HIRUDIN VARIANT 2 (3 entities in total) |
Functional Keywords | hydrolase(serine protease) |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted, extracellular space: P00734 P00734 Secreted: P09945 |
Total number of polymer chains | 3 |
Total formula weight | 40794.26 |
Authors | Tulinsky, A.,Rydel, T.J.,Ravichandran, K.G.,Huber, R.,Bode, W. (deposition date: 1993-06-11, release date: 1994-01-31, Last modification date: 2024-02-21) |
Primary citation | Rydel, T.J.,Ravichandran, K.G.,Tulinsky, A.,Bode, W.,Huber, R.,Roitsch, C.,Fenton 2nd., J.W. The structure of a complex of recombinant hirudin and human alpha-thrombin. Science, 249:277-280, 1990 Cited by PubMed: 2374926PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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