Molecular function of proteins are determined by their three dimensional structures, thus the similarity of protein structure can give some clues to infer their functions. In many cases, the molecular function are begun with the molecular interaction with small molecules (ligands). eF-seek is a web server to search for the similar ligand binding sites for the uploaded coordinate file with PDB format. The representative binding sites in eF-site database are search by our own algorithm based on the clique search algorithm.
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