3HTC

THE STRUCTURE OF A COMPLEX OF RECOMBINANT HIRUDIN AND HUMAN ALPHA-THROMBIN

Summary for 3HTC

• Entry DOI: 10.2210/pdb3htc/pdb
• Descriptor: ALPHA-THROMBIN (SMALL SUBUNIT), ALPHA-THROMBIN (LARGE SUBUNIT), HIRUDIN VARIANT 2 (3 entities in total)
• Functional Keywords: hydrolase(serine protease)
• Biological source: Homo sapiens (human); More
• Cellular location: Secreted, extracellular space: P00734 P00734; Secreted: P09945
• Total number of polymer chains: 3
• Total formula weight: 40794.26

Authors

Tulinsky, A.,Rydel, T.J.,Ravichandran, K.G.,Huber, R.,Bode, W. (deposition date: 1993-06-11, release date: 1994-01-31, Last modification date: 2024-02-21)

• Primary citation: Rydel, T.J.,Ravichandran, K.G.,Tulinsky, A.,Bode, W.,Huber, R.,Roitsch, C.,Fenton 2nd., J.W.; The structure of a complex of recombinant hirudin and human alpha-thrombin.; Science, 249:277-280, 1990; PubMed: 2374926

Experimental method

X-RAY DIFFRACTION (2.3 Å)