1UVS

BOVINE THROMBIN--BM51.1011 COMPLEX

Summary for 1UVS

• Entry DOI: 10.2210/pdb1uvs/pdb
• Descriptor: THROMBIN, [[CYCLOHEXANESULFONYL-GLYCYL]-3[PYRIDIN-4-YL-AMINOMETHYL]ALANYL]PIPERIDINE, ... (4 entities in total)
• Functional Keywords: serine protease, hydrolase, thrombin, blood coagulation
• Biological source: Homo sapiens (human); More
• Cellular location: Secreted, extracellular space: P00734 P00734
• Total number of polymer chains: 2
• Total formula weight: 34343.37

Authors

Engh, R.A.,Huber, R. (deposition date: 1996-10-16, release date: 1997-11-19, Last modification date: 2011-07-13)

• Primary citation: Engh, R.A.,Brandstetter, H.,Sucher, G.,Eichinger, A.,Baumann, U.,Bode, W.,Huber, R.,Poll, T.,Rudolph, R.,von der Saal, W.; Enzyme flexibility, solvent and 'weak' interactions characterize thrombin-ligand interactions: implications for drug design.; Structure, 4:1353-1362, 1996; PubMed: 8939759; DOI: 10.1016/S0969-2126(96)00142-6

Experimental method

X-RAY DIFFRACTION (2.8 Å)