1NRR

Crystallographic structures of Thrombin complexed with Thrombin receptor peptides: Existence of expected and novel binding modes

Summary for 1NRR

Entry DOI	10.2210/pdb1nrr/pdb
Related PRD ID	PRD_000020
Descriptor	Thrombin light chain, Thrombin heavy chain, Proteinase-activated receptor 1, ... (5 entities in total)
Functional Keywords	hydrolase-hydrolase inhibitor complex, blood clotting, hydrolase/hydrolase inhibitor
Biological source	Homo sapiens (human) More
Cellular location	Secreted, extracellular space: P00734 P00734 Cell membrane; Multi-pass membrane protein: P25116
Total number of polymer chains	3
Total formula weight	36674.24
Authors	Tulinsky, A.,Mathews, I.I. (deposition date: 1994-01-18, release date: 1994-05-31, Last modification date: 2013-02-27)
Primary citation	Mathews, I.I.,Padmanabhan, K.P.,Ganesh, V.,Tulinsky, A.,Ishii, M.,Chen, J.,Turck, C.W.,Coughlin, S.R.,Fenton 2nd., J.W. Crystallographic structures of thrombin complexed with thrombin receptor peptides: existence of expected and novel binding modes. Biochemistry, 33:3266-3279, 1994 Cited by PubMed: 8136362 DOI: 10.1021/bi00177a018 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.4 Å)

Structure validation