1NRR

Crystallographic structures of Thrombin complexed with Thrombin receptor peptides: Existence of expected and novel binding modes

Summary for 1NRR
Related PRD IDPRD_000020
DescriptorThrombin light chain, Thrombin heavy chain, Proteinase-activated receptor 1, ... (5 entities in total)
Functional Keywordshydrolase-hydrolase inhibitor complex, blood clotting, hydrolase/hydrolase inhibitor
Biological sourceHomo sapiens (human)
More
Cellular locationSecreted, extracellular space: P00734 P00734
Cell membrane; Multi-pass membrane protein: P25116
Total number of polymer chains3
Total formula weight36674.24
Authors
Tulinsky, A.,Mathews, I.I. (deposition date: 1994-01-18, release date: 1994-05-31, Last modification date: 2013-02-27)
Primary citationChen, J.,Coughlin, S.R.,Fenton 2nd., J.W.,Ganesh, V.,Ishii, M.,Mathews, I.I.,Padmanabhan, K.P.,Tulinsky, A.,Turck, C.W.
Crystallographic structures of thrombin complexed with thrombin receptor peptides: existence of expected and novel binding modes.
Biochemistry, 33:3266-3279, 1994
PubMed: 8136362
DOI: 110.1021/bi00177a018
PDB entries with the same primary citation
Experimental method
X-RAY DIFFRACTION (2.4 Å)
Structure validation
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PDB entries from 2021-06-23