1BA8
THROMBIN INHIBITOR WITH A RIGID TRIPEPTIDYL ALDEHYDES
Summary for 1BA8
Entry DOI | 10.2210/pdb1ba8/pdb |
Related PRD ID | PRD_000322 |
Descriptor | THROMBIN, HIRUGEN, amino({(4S)-4-[({(3S)-3-[(benzylsulfonyl)amino]-2-oxopiperidin-1-yl}acetyl)amino]-5-oxopentyl}amino)methaniminium, ... (6 entities in total) |
Functional Keywords | hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
Biological source | Hirudo medicinalis (medicinal leech) More |
Total number of polymer chains | 3 |
Total formula weight | 36127.10 |
Authors | Krishnan, R.,Zhang, E.,Hakansson, K.,Arni, R.K.,Tulinsky, A.,Lim-Wilby, M.S.L.,Levy, O.E.,Semple, J.E.,Brunck, T.K. (deposition date: 1998-04-23, release date: 1999-04-27, Last modification date: 2023-08-02) |
Primary citation | Krishnan, R.,Zhang, E.,Hakansson, K.,Arni, R.K.,Tulinsky, A.,Lim-Wilby, M.S.,Levy, O.E.,Semple, J.E.,Brunck, T.K. Highly selective mechanism-based thrombin inhibitors: structures of thrombin and trypsin inhibited with rigid peptidyl aldehydes. Biochemistry, 37:12094-12103, 1998 Cited by PubMed: 9724521DOI: 10.1021/bi980840e PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.8 Å) |
Structure validation
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