1BHX

X-RAY STRUCTURE OF THE COMPLEX OF HUMAN ALPHA THROMBIN WITH THE INHIBITOR SDZ 229-357

Summary for 1BHX

Entry DOI	10.2210/pdb1bhx/pdb
Descriptor	ALPHA THROMBIN, 5-OXO-6-PHENYLMETHANESULFONYLAMINO-HEXAHYDRO-THIAZOLO[3,2-A]PYRIDINE-3-CARBOXYLIC ACID (3-GUANIDINO-PROPYL)-AMIDE, ... (6 entities in total)
Functional Keywords	serine protease
Biological source	Homo sapiens (human) More
Cellular location	Secreted, extracellular space: P00734 P00734 P00734
Total number of polymer chains	4
Total formula weight	33622.49
Authors	Kallen, J. (deposition date: 1998-06-10, release date: 1998-11-04, Last modification date: 2023-08-02)
Primary citation	Wagner, J.,Kallen, J.,Ehrhardt, C.,Evenou, J.P.,Wagner, D. Rational design, synthesis, and X-ray structure of selective noncovalent thrombin inhibitors. J.Med.Chem., 41:3664-3674, 1998 Cited by PubMed: 9733491 DOI: 10.1021/jm981013e PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation