1BHX
X-RAY STRUCTURE OF THE COMPLEX OF HUMAN ALPHA THROMBIN WITH THE INHIBITOR SDZ 229-357
Summary for 1BHX
Entry DOI | 10.2210/pdb1bhx/pdb |
Descriptor | ALPHA THROMBIN, 5-OXO-6-PHENYLMETHANESULFONYLAMINO-HEXAHYDRO-THIAZOLO[3,2-A]PYRIDINE-3-CARBOXYLIC ACID (3-GUANIDINO-PROPYL)-AMIDE, ... (6 entities in total) |
Functional Keywords | serine protease |
Biological source | Homo sapiens (human) More |
Cellular location | Secreted, extracellular space: P00734 P00734 P00734 |
Total number of polymer chains | 4 |
Total formula weight | 33622.49 |
Authors | Kallen, J. (deposition date: 1998-06-10, release date: 1998-11-04, Last modification date: 2023-08-02) |
Primary citation | Wagner, J.,Kallen, J.,Ehrhardt, C.,Evenou, J.P.,Wagner, D. Rational design, synthesis, and X-ray structure of selective noncovalent thrombin inhibitors. J.Med.Chem., 41:3664-3674, 1998 Cited by PubMed: 9733491DOI: 10.1021/jm981013e PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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