1BTH
STRUCTURE OF THROMBIN COMPLEXED WITH BOVINE PANCREATIC TRYPSIN INHIBITOR
Summary for 1BTH
Entry DOI | 10.2210/pdb1bth/pdb |
Descriptor | THROMBIN, BOVINE PANCREATIC TRYPSIN INHIBITOR, ... (4 entities in total) |
Functional Keywords | thrombin inhibitor, serine proteinase kunitz-like inhibitor, (serine protease/inhibitor), complex (serine protease-inhibitor) complex, complex (serine protease/inhibitor) |
Biological source | Bos taurus (cattle) More |
Cellular location | Secreted, extracellular space: P00734 P00734 Secreted: P00974 |
Total number of polymer chains | 6 |
Total formula weight | 80866.73 |
Authors | Van De Locht, A.,Bode, W.,Stubbs, M.T. (deposition date: 1996-12-03, release date: 1997-12-24, Last modification date: 2021-11-03) |
Primary citation | van de Locht, A.,Bode, W.,Huber, R.,Le Bonniec, B.F.,Stone, S.R.,Esmon, C.T.,Stubbs, M.T. The thrombin E192Q-BPTI complex reveals gross structural rearrangements: implications for the interaction with antithrombin and thrombomodulin. EMBO J., 16:2977-2984, 1997 Cited by PubMed: 9214615DOI: 10.1093/emboj/16.11.2977 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.3 Å) |
Structure validation
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