1BTH

STRUCTURE OF THROMBIN COMPLEXED WITH BOVINE PANCREATIC TRYPSIN INHIBITOR

Summary for 1BTH

Entry DOI	10.2210/pdb1bth/pdb
Descriptor	THROMBIN, BOVINE PANCREATIC TRYPSIN INHIBITOR, ... (4 entities in total)
Functional Keywords	thrombin inhibitor, serine proteinase kunitz-like inhibitor, (serine protease/inhibitor), complex (serine protease-inhibitor) complex, complex (serine protease/inhibitor)
Biological source	Bos taurus (cattle) More
Cellular location	Secreted, extracellular space: P00734 P00734 Secreted: P00974
Total number of polymer chains	6
Total formula weight	80866.73
Authors	Van De Locht, A.,Bode, W.,Stubbs, M.T. (deposition date: 1996-12-03, release date: 1997-12-24, Last modification date: 2021-11-03)
Primary citation	van de Locht, A.,Bode, W.,Huber, R.,Le Bonniec, B.F.,Stone, S.R.,Esmon, C.T.,Stubbs, M.T. The thrombin E192Q-BPTI complex reveals gross structural rearrangements: implications for the interaction with antithrombin and thrombomodulin. EMBO J., 16:2977-2984, 1997 Cited by PubMed: 9214615 DOI: 10.1093/emboj/16.11.2977 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation