1UMA

ALPHA-THROMBIN (HIRUGEN) COMPLEXED WITH NA-(N,N-DIMETHYLCARBAMOYL)-ALPHA-AZALYSINE

Summary for 1UMA

• Entry DOI: 10.2210/pdb1uma/pdb
• Descriptor: ALPHA-THROMBIN, HIRUDIN I, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total)
• Functional Keywords: hydrolase-hydrolase inhibitor complex, serine protease, kringle, alpha-thrombin- hirugen complex, hydrolase/hydrolase inhibitor
• Biological source: Homo sapiens (human); More
• Total number of polymer chains: 3
• Total formula weight: 35897.87

Authors

Nardini, M.,Pesce, A.,Rizzi, M.,Casale, E.,Ferraccioli, R.,Balliano, G.,Milla, P.,Ascenzi, P.,Bolognesi, M. (deposition date: 1996-03-26, release date: 1996-11-08, Last modification date: 2020-07-29)

• Primary citation: Nardini, M.,Pesce, A.,Rizzi, M.,Casale, E.,Ferraccioli, R.,Balliano, G.,Milla, P.,Ascenzi, P.,Bolognesi, M.; Human alpha-thrombin inhibition by the active site titrant N alpha-(N,N-dimethylcarbamoyl)-alpha-azalysine p-nitrophenyl ester: a comparative kinetic and X-ray crystallographic study.; J.Mol.Biol., 258:851-859, 1996; PubMed: 8637015; DOI: 10.1006/jmbi.1996.0292

Experimental method

X-RAY DIFFRACTION (2 Å)