1UMA
ALPHA-THROMBIN (HIRUGEN) COMPLEXED WITH NA-(N,N-DIMETHYLCARBAMOYL)-ALPHA-AZALYSINE
Summary for 1UMA
Entry DOI | 10.2210/pdb1uma/pdb |
Descriptor | ALPHA-THROMBIN, HIRUDIN I, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... (6 entities in total) |
Functional Keywords | hydrolase-hydrolase inhibitor complex, serine protease, kringle, alpha-thrombin- hirugen complex, hydrolase/hydrolase inhibitor |
Biological source | Homo sapiens (human) More |
Total number of polymer chains | 3 |
Total formula weight | 35897.87 |
Authors | Nardini, M.,Pesce, A.,Rizzi, M.,Casale, E.,Ferraccioli, R.,Balliano, G.,Milla, P.,Ascenzi, P.,Bolognesi, M. (deposition date: 1996-03-26, release date: 1996-11-08, Last modification date: 2020-07-29) |
Primary citation | Nardini, M.,Pesce, A.,Rizzi, M.,Casale, E.,Ferraccioli, R.,Balliano, G.,Milla, P.,Ascenzi, P.,Bolognesi, M. Human alpha-thrombin inhibition by the active site titrant N alpha-(N,N-dimethylcarbamoyl)-alpha-azalysine p-nitrophenyl ester: a comparative kinetic and X-ray crystallographic study. J.Mol.Biol., 258:851-859, 1996 Cited by PubMed: 8637015DOI: 10.1006/jmbi.1996.0292 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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