1ABI

STRUCTURE OF THE HIRULOG 3-THROMBIN COMPLEX AND NATURE OF THE S' SUBSITES OF SUBSTRATES AND INHIBITORS

Summary for 1ABI

Entry DOI	10.2210/pdb1abi/pdb
Descriptor	ALPHA-THROMBIN (SMALL SUBUNIT), ALPHA-THROMBIN (LARGE SUBUNIT), HIRULOG 3, ... (4 entities in total)
Functional Keywords	hydrolase(serine proteinase), hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor
Biological source	Homo sapiens (human) More
Cellular location	Secreted, extracellular space: P00734 P00734 Secreted: P28504
Total number of polymer chains	3
Total formula weight	36031.00
Authors	Qiu, X.,Tulinsky, A. (deposition date: 1992-08-24, release date: 1994-01-31, Last modification date: 2023-11-15)
Primary citation	Qiu, X.,Padmanabhan, K.P.,Carperos, V.E.,Tulinsky, A.,Kline, T.,Maraganore, J.M.,Fenton 2nd., J.W. Structure of the hirulog 3-thrombin complex and nature of the S' subsites of substrates and inhibitors. Biochemistry, 31:11689-11697, 1992 Cited by PubMed: 1445905 DOI: 10.1021/bi00162a004 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.3 Å)

Structure validation