1UVT
BOVINE THROMBIN--BM14.1248 COMPLEX
Summary for 1UVT
Entry DOI | 10.2210/pdb1uvt/pdb |
Descriptor | THROMBIN, N-{3-METHYL-5-[2-(PYRIDIN-4-YLAMINO)-ETHOXY]-PHENYL}-BENZENESULFONAMIDE, ... (4 entities in total) |
Functional Keywords | serine protease, hydrolase, thrombin, blood coagulation |
Biological source | Bos taurus (cattle) More |
Cellular location | Secreted, extracellular space: P00735 P00735 |
Total number of polymer chains | 2 |
Total formula weight | 35892.13 |
Authors | Engh, R.A.,Huber, R. (deposition date: 1996-10-16, release date: 1997-11-19, Last modification date: 2024-06-05) |
Primary citation | Engh, R.A.,Brandstetter, H.,Sucher, G.,Eichinger, A.,Baumann, U.,Bode, W.,Huber, R.,Poll, T.,Rudolph, R.,von der Saal, W. Enzyme flexibility, solvent and 'weak' interactions characterize thrombin-ligand interactions: implications for drug design. Structure, 4:1353-1362, 1996 Cited by PubMed: 8939759DOI: 10.1016/S0969-2126(96)00142-6 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (2.5 Å) |
Structure validation
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