1AD8
COMPLEX OF THROMBIN WITH AND INHIBITOR CONTAINING A NOVEL P1 MOIETY
Summary for 1AD8
| Entry DOI | 10.2210/pdb1ad8/pdb |
| Descriptor | THROMBIN (SMALL SUBUNIT), THROMBIN (LARGE SUBUNIT), HIRUDIN (53-65) PEPTIDE, ... (6 entities in total) |
| Functional Keywords | complex (serine protease-inhibitor), hydrolase, serine protease, coagulant, inhibitor, hydrolase-hydrolase inhibitor complex, hydrolase/hydrolase inhibitor |
| Biological source | Hirudo medicinalis (medicinal leech) More |
| Cellular location | Secreted, extracellular space: P00734 P00734 Secreted: P01050 |
| Total number of polymer chains | 3 |
| Total formula weight | 35827.69 |
| Authors | Schreuder, H.,Tardif, C.,Malikayil, J.A. (deposition date: 1997-02-24, release date: 1997-11-12, Last modification date: 2024-04-03) |
| Primary citation | Malikayil, J.A.,Burkhart, J.P.,Schreuder, H.A.,Broersma Jr., R.J.,Tardif, C.,Kutcher 3rd., L.W.,Mehdi, S.,Schatzman, G.L.,Neises, B.,Peet, N.P. Molecular design and characterization of an alpha-thrombin inhibitor containing a novel P1 moiety. Biochemistry, 36:1034-1040, 1997 Cited by PubMed: 9033393DOI: 10.1021/bi9622231 PDB entries with the same primary citation |
| Experimental method | X-RAY DIFFRACTION (2 Å) |
Structure validation
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