6CMO
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![BU of 6cmo by Molmil](/molmil-images/mine/6cmo) | Rhodopsin-Gi complex | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab Heavy chain, Fab light chain, ... | Authors: | Kang, Y, Kuybeda, O, de Waal, P.W, Mukherjee, S, Van Eps, N, Dutka, P, Zhou, X.E, Bartesaghi, A, Erramilli, S, Morizumi, T, Gu, X, Yin, Y, Liu, P, Jiang, Y, Meng, X, Zhao, G, Melcher, K, Earnst, O.P, Kossiakoff, A.A, Subramaniam, S, Xu, H.E. | Deposit date: | 2018-03-05 | Release date: | 2018-06-20 | Last modified: | 2020-07-29 | Method: | ELECTRON MICROSCOPY (4.5 Å) | Cite: | Cryo-EM structure of human rhodopsin bound to an inhibitory G protein. Nature, 558, 2018
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6DNH
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![BU of 6dnh by Molmil](/molmil-images/mine/6dnh) | Cryo-EM structure of human CPSF-160-WDR33-CPSF-30-PAS RNA complex at 3.4 A resolution | Descriptor: | Cleavage and polyadenylation specificity factor subunit 1, Cleavage and polyadenylation specificity factor subunit 4, RNA (5'-R(P*AP*AP*UP*AP*AP*AP*C)-3'), ... | Authors: | Sun, Y, Zhang, Y, Hamilton, K, Walz, T, Tong, L. | Deposit date: | 2018-06-06 | Release date: | 2018-06-27 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (3.4 Å) | Cite: | Molecular basis for the recognition of the human AAUAAA polyadenylation signal. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6D9J
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![BU of 6d9j by Molmil](/molmil-images/mine/6d9j) | Mammalian 80S ribosome with a double translocated CrPV-IRES, P-sitetRNA and eRF1. | Descriptor: | 18S rRNA, 28S rRNA, 5.8S rRNA, ... | Authors: | Pisareva, V.P, Pisarev, A.V, Fernandez, I.S. | Deposit date: | 2018-04-30 | Release date: | 2018-06-06 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Dual tRNA mimicry in the Cricket Paralysis Virus IRES uncovers an unexpected similarity with the Hepatitis C Virus IRES. Elife, 7, 2018
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6DDE
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![BU of 6dde by Molmil](/molmil-images/mine/6dde) | Mu Opioid Receptor-Gi Protein Complex | Descriptor: | DAMGO, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... | Authors: | Koehl, A, Hu, H, Maeda, S, Manglik, A, Zhang, Y, Kobilka, B.K, Skiniotis, G, Weis, W.I. | Deposit date: | 2018-05-10 | Release date: | 2018-06-13 | Last modified: | 2023-11-15 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structure of the mu-opioid receptor-Giprotein complex. Nature, 558, 2018
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6DEC
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![BU of 6dec by Molmil](/molmil-images/mine/6dec) | |
6D9H
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![BU of 6d9h by Molmil](/molmil-images/mine/6d9h) | Cryo-EM structure of the human adenosine A1 receptor-Gi2-protein complex bound to its endogenous agonist | Descriptor: | ADENOSINE, Chimera protein of Muscarinic acetylcholine receptor M4 and Adenosine receptor A1, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Draper-Joyce, C.J, Khoshouei, M, Thal, D.M, Liang, Y.-L, Nguyen, A.T.N, Furness, S.G.B, Venugopal, H, Baltos, J, Plitzko, J.M, Danev, R, Baumeister, W, May, L.T, Wootten, D, Sexton, P, Glukhova, A, Christopoulos, A. | Deposit date: | 2018-04-29 | Release date: | 2018-06-20 | Last modified: | 2018-07-11 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structure of the adenosine-bound human adenosine A1receptor-Gicomplex. Nature, 558, 2018
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6D90
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![BU of 6d90 by Molmil](/molmil-images/mine/6d90) | Mammalian 80S ribosome with a double translocated CrPV-IRES, P-site tRNA and eRF1. | Descriptor: | 18S rRNA, 28S rRNA, 5.8S rRNA, ... | Authors: | Pisareva, V.P, Pisarev, A.V, Fernandez, I.S. | Deposit date: | 2018-04-27 | Release date: | 2018-06-06 | Last modified: | 2019-12-18 | Method: | ELECTRON MICROSCOPY (3.2 Å) | Cite: | Dual tRNA mimicry in the Cricket Paralysis Virus IRES uncovers an unexpected similarity with the Hepatitis C Virus IRES. Elife, 7, 2018
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3J6Y
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![BU of 3j6y by Molmil](/molmil-images/mine/3j6y) | S. cerevisiae 80S ribosome bound with Taura syndrome virus (TSV) IRES, 2 degree rotation (Class I) | Descriptor: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0, ... | Authors: | Koh, C.S, Brilot, A.F, Grigorieff, N, Korostelev, A.A. | Deposit date: | 2014-04-16 | Release date: | 2014-06-11 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (6.1 Å) | Cite: | Taura syndrome virus IRES initiates translation by binding its tRNA-mRNA-like structural element in the ribosomal decoding center. Proc.Natl.Acad.Sci.USA, 111, 2014
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3JAG
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![BU of 3jag by Molmil](/molmil-images/mine/3jag) | Structure of a mammalian ribosomal termination complex with ABCE1, eRF1(AAQ), and the UAA stop codon | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ... | Authors: | Brown, A, Shao, S, Murray, J, Hegde, R.S, Ramakrishnan, V. | Deposit date: | 2015-06-10 | Release date: | 2015-08-12 | Last modified: | 2018-07-18 | Method: | ELECTRON MICROSCOPY (3.65 Å) | Cite: | Structural basis for stop codon recognition in eukaryotes. Nature, 524, 2015
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3J7P
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![BU of 3j7p by Molmil](/molmil-images/mine/3j7p) | Structure of the 80S mammalian ribosome bound to eEF2 | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ... | Authors: | Voorhees, R.M, Fernandez, I.S, Scheres, S.H.W, Hegde, R.S. | Deposit date: | 2014-08-01 | Release date: | 2014-09-03 | Last modified: | 2018-07-18 | Method: | ELECTRON MICROSCOPY (3.5 Å) | Cite: | Structure of the Mammalian ribosome-sec61 complex to 3.4 a resolution. Cell(Cambridge,Mass.), 157, 2014
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3JAM
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![BU of 3jam by Molmil](/molmil-images/mine/3jam) | CryoEM structure of 40S-eIF1A-eIF1 complex from yeast | Descriptor: | 18S rRNA, MAGNESIUM ION, RACK1, ... | Authors: | Llacer, J.L, Hussain, T, Ramakrishnan, V. | Deposit date: | 2015-06-17 | Release date: | 2015-08-12 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.46 Å) | Cite: | Conformational Differences between Open and Closed States of the Eukaryotic Translation Initiation Complex. Mol.Cell, 59, 2015
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3JB9
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![BU of 3jb9 by Molmil](/molmil-images/mine/3jb9) | Cryo-EM structure of the yeast spliceosome at 3.6 angstrom resolution | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ... | Authors: | Yan, C, Hang, J, Wan, R, Huang, M, Wong, C, Shi, Y. | Deposit date: | 2015-08-09 | Release date: | 2015-09-23 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structure of a yeast spliceosome at 3.6-angstrom resolution Science, 349, 2015
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6HHQ
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![BU of 6hhq by Molmil](/molmil-images/mine/6hhq) | Crystal structure of compound C45 bound to the yeast 80S ribosome | Descriptor: | (3~{R})-3-[(1~{S})-2-[(1~{S},4~{a}~{R},6~{S},7~{S},8~{a}~{R})-6,7-bis(chloranyl)-5,5,8~{a}-trimethyl-2-methylidene-3,4,4~{a},6,7,8-hexahydro-1~{H}-naphthalen-1-yl]-1-oxidanyl-ethyl]pyrrolidine-2,5-dione, 18S ribosomal RNA, 25S ribosomal RNA, ... | Authors: | Pellegrino, S, Vanderwal, C.D, Yusupov, M. | Deposit date: | 2018-08-28 | Release date: | 2019-02-20 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (3.10000038 Å) | Cite: | Understanding the role of intermolecular interactions between lissoclimides and the eukaryotic ribosome. Nucleic Acids Res., 47, 2019
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6HCJ
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![BU of 6hcj by Molmil](/molmil-images/mine/6hcj) | Structure of the rabbit 80S ribosome on globin mRNA in the rotated state with A/P and P/E tRNAs | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... | Authors: | Juszkiewicz, S, Chandrasekaran, V, Lin, Z, Kraatz, S, Ramakrishnan, V, Hegde, R.S. | Deposit date: | 2018-08-15 | Release date: | 2018-10-17 | Last modified: | 2018-11-14 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | ZNF598 Is a Quality Control Sensor of Collided Ribosomes. Mol. Cell, 72, 2018
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6HCQ
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![BU of 6hcq by Molmil](/molmil-images/mine/6hcq) | Structure of the rabbit collided di-ribosome (collided monosome) | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... | Authors: | Juszkiewicz, S, Chandrasekaran, V, Lin, Z, Kraatz, S, Ramakrishnan, V, Hegde, R.S. | Deposit date: | 2018-08-16 | Release date: | 2018-10-17 | Last modified: | 2018-11-14 | Method: | ELECTRON MICROSCOPY (6.5 Å) | Cite: | ZNF598 Is a Quality Control Sensor of Collided Ribosomes. Mol. Cell, 72, 2018
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3J6X
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![BU of 3j6x by Molmil](/molmil-images/mine/3j6x) | S. cerevisiae 80S ribosome bound with Taura syndrome virus (TSV) IRES, 5 degree rotation (Class II) | Descriptor: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0, ... | Authors: | Koh, C.S, Brilot, A.F, Grigorieff, N, Korostelev, A.A. | Deposit date: | 2014-04-16 | Release date: | 2014-06-11 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (6.1 Å) | Cite: | Taura syndrome virus IRES initiates translation by binding its tRNA-mRNA-like structural element in the ribosomal decoding center. Proc.Natl.Acad.Sci.USA, 111, 2014
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6K41
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![BU of 6k41 by Molmil](/molmil-images/mine/6k41) | cryo-EM structure of alpha2BAR-GoA complex | Descriptor: | 4-[(1~{S})-1-(2,3-dimethylphenyl)ethyl]-1~{H}-imidazole, Alpha-2A adrenergic receptor,Endolysin,Alpha-2B adrenergic receptor,Alpha-2B adrenergic receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... | Authors: | Yuan, D, Liu, Z, Wang, H.W, Kobilka, B.K. | Deposit date: | 2019-05-23 | Release date: | 2020-04-15 | Last modified: | 2020-05-13 | Method: | ELECTRON MICROSCOPY (2.9 Å) | Cite: | Activation of the alpha2Badrenoceptor by the sedative sympatholytic dexmedetomidine. Nat.Chem.Biol., 16, 2020
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3J80
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![BU of 3j80 by Molmil](/molmil-images/mine/3j80) | CryoEM structure of 40S-eIF1-eIF1A preinitiation complex | Descriptor: | 18S rRNA, MAGNESIUM ION, RACK1, ... | Authors: | Hussain, T, Llacer, J.L, Fernandez, I.S, Savva, C.G, Ramakrishnan, V. | Deposit date: | 2014-08-28 | Release date: | 2014-11-05 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (3.75 Å) | Cite: | Structural changes enable start codon recognition by the eukaryotic translation initiation complex. Cell(Cambridge,Mass.), 159, 2014
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3JCM
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![BU of 3jcm by Molmil](/molmil-images/mine/3jcm) | Cryo-EM structure of the spliceosomal U4/U6.U5 tri-snRNP | Descriptor: | 13 kDa ribonucleoprotein-associated protein, GUANOSINE-5'-TRIPHOSPHATE, N,N,7-trimethylguanosine 5'-(trihydrogen diphosphate), ... | Authors: | Wan, R, Yan, C, Bai, R, Wang, L, Huang, M, Wong, C.C, Shi, Y. | Deposit date: | 2015-12-23 | Release date: | 2016-02-24 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | The 3.8 angstrom structure of the U4/U6.U5 tri-snRNP: Insights into spliceosome assembly and catalysis Science, 351, 2016
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3J77
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![BU of 3j77 by Molmil](/molmil-images/mine/3j77) | Structures of yeast 80S ribosome-tRNA complexes in the rotated and non-rotated conformations (Class II - rotated ribosome with 1 tRNA) | Descriptor: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0, ... | Authors: | Svidritskiy, E, Brilot, A.F, Koh, C.S, Grigorieff, N, Korostelev, A.A. | Deposit date: | 2014-05-29 | Release date: | 2014-08-06 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (6.2 Å) | Cite: | Structures of Yeast 80S Ribosome-tRNA Complexes in the Rotated and Nonrotated Conformations. Structure, 22, 2014
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6ID1
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![BU of 6id1 by Molmil](/molmil-images/mine/6id1) | Cryo-EM structure of a human intron lariat spliceosome after Prp43 loaded (ILS2 complex) at 2.9 angstrom resolution | Descriptor: | 116 kDa U5 small nuclear ribonucleoprotein component, CWF19-like protein 2, Cell division cycle 5-like protein, ... | Authors: | Zhang, X, Zhan, X, Yan, C, Shi, Y. | Deposit date: | 2018-09-07 | Release date: | 2019-03-13 | Last modified: | 2020-10-14 | Method: | ELECTRON MICROSCOPY (2.86 Å) | Cite: | Structures of the human spliceosomes before and after release of the ligated exon. Cell Res., 29, 2019
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6I7O
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![BU of 6i7o by Molmil](/molmil-images/mine/6i7o) | The structure of a di-ribosome (disome) as a unit for RQC and NGD quality control pathways recognition. | Descriptor: | 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0-A, ... | Authors: | Tesina, P, Cheng, J, Becker, T, Beckmann, R. | Deposit date: | 2018-11-16 | Release date: | 2019-01-16 | Last modified: | 2019-03-13 | Method: | ELECTRON MICROSCOPY (5.3 Å) | Cite: | Collided ribosomes form a unique structural interface to induce Hel2-driven quality control pathways. EMBO J., 38, 2019
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6IP5
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![BU of 6ip5 by Molmil](/molmil-images/mine/6ip5) | Cryo-EM structure of the CMV-stalled human 80S ribosome (Structure ii) | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S10, ... | Authors: | Yokoyama, T, Shigematsu, H, Shirouzu, M, Imataka, H, Ito, T. | Deposit date: | 2018-11-02 | Release date: | 2019-05-29 | Last modified: | 2019-11-06 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | HCV IRES Captures an Actively Translating 80S Ribosome. Mol.Cell, 74, 2019
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3JCR
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![BU of 3jcr by Molmil](/molmil-images/mine/3jcr) | 3D structure determination of the human*U4/U6.U5* tri-snRNP complex | Descriptor: | LSm2, LSm3, LSm4, ... | Authors: | Agafonov, D.E, Kastner, B, Dybkov, O, Hofele, R.V, Liu, W.T, Urlaub, H, Luhrmann, R, Stark, H. | Deposit date: | 2016-01-21 | Release date: | 2016-03-09 | Last modified: | 2024-02-21 | Method: | ELECTRON MICROSCOPY (7 Å) | Cite: | Molecular architecture of the human U4/U6.U5 tri-snRNP. Science, 351, 2016
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6HCF
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![BU of 6hcf by Molmil](/molmil-images/mine/6hcf) | Structure of the rabbit 80S ribosome stalled on globin mRNA at the stop codon | Descriptor: | 18S ribosomal RNA, 28S ribosomal RNA, 40S ribosomal protein S12, ... | Authors: | Juszkiewicz, S, Chandrasekaran, V, Lin, Z, Kraatz, S, Ramakrishnan, V, Hegde, R.S. | Deposit date: | 2018-08-14 | Release date: | 2018-10-17 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.9 Å) | Cite: | ZNF598 Is a Quality Control Sensor of Collided Ribosomes. Mol. Cell, 72, 2018
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