S. cerevisiae 80S ribosome bound with Taura syndrome virus (TSV) IRES, 2 degree rotation (Class I)

This is a large structure.

Summary for 3J6Y

Integrates1VWS 1VWU 1VWV
EMDB information5943 5942
Descriptor25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... (80 entities in total)
Functional Keywordstranslation initiation, ribosome, intergenic ires, tsv ires
Biological sourceSaccharomyces cerevisiae (yeast)
Total number of polymer chains80
Total molecular weight3194034.32
Koh, C.S.,Brilot, A.F.,Grigorieff, N.,Korostelev, A.A. (deposition date: 2014-04-16, release date: 2014-06-11, Last modification date: 2018-07-18)
Primary citation
Koh, C.S.,Brilot, A.F.,Grigorieff, N.,Korostelev, A.A.
Taura syndrome virus IRES initiates translation by binding its tRNA-mRNA-like structural element in the ribosomal decoding center.
Proc.Natl.Acad.Sci.USA, 111:9139-9144, 2014
PubMed: 24927574 (PDB entries with the same primary citation)
DOI: 10.1073/pnas.1406335111
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliersRNA backbone234.3%7.6%0.50MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures