3J7P

Structure of the 80S mammalian ribosome bound to eEF2

This is a large structure.
Replaces:  3J74

> Summary

Summary for 3J7P

Related3J7O 3J7Q 3J7R
Integrates4W21 4W22 4W23
EMDB informationEMD-2644 EMD-2646 EMD-2649 EMD-2650
DescriptorPROTEIN/RNA Complex
Functional Keywordsmammalian, sec61, translocation, translation, eef2, ribosome
Biological sourceSus scrofa (pig)
Cellular locationCell membrane  Q4GWZ2
Cytoplasm  B6V8C8 Q0Z8U2 P62272 A1XQU9 P83884
Cell membrane ; Peripheral membrane protein  P63246
Nucleus, nucleolus  Q29205
Ubiquitin: Cytoplasm . 60S ribosomal protein L40: Cytoplasm  P63053
Total number of polymer chains82
Total molecular weight3407336.47
Authors
Voorhees, R.M.,Fernandez, I.S.,Scheres, S.H.W.,Hegde, R.S. (deposition date: 2014-08-01, release date: 2014-09-03, modification date: 2015-04-15)
Primary citation
Voorhees, R.M.,Fernandez, I.S.,Scheres, S.H.,Hegde, R.S.
Structure of the Mammalian ribosome-sec61 complex to 3.4 a resolution.
Cell(Cambridge,Mass.), 157:1632-1643, 2014
PubMed: 24930395
DOI: 10.1016/j.cell.2014.05.024
MImport into Mendeley
Experimental method
ELECTRON MICROSCOPY
?

Structure validation

ClashscoreRamachandran outliersSidechain outliersRNA backbone615.4%20.1%0.28MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures

More Asymmetric unit images

Molmil generated image of 3j7p
no rotation
Molmil generated image of 3j7p
rotated about x axis by 90°
Molmil generated image of 3j7p
rotated about y axis by 90°

> Structural details

Entity

Chain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
528S ribosomal RNApolymer36641187231.11
Sus scrofa (pig)
75S ribosomal RNApolymer12038692.11
Sus scrofa (pig)
85.8S ribosomal RNApolymer15650144.01
Sus scrofa (pig)
ARibosomal protein uL2polymer25728089.11
UniProt (F2Z567)
Pfam (PF00181)
Pfam (PF03947)
Sus scrofa (pig)
BRibosomal protein uL3polymer39444759.81
Sus scrofa (pig)
CRibosomal protein uL4polymer36741635.51
Sus scrofa (pig)
DRibosomal protein uL18polymer29734418.01
UniProt (F1S530)
Pfam (PF14204)
Pfam (PF17144)
Sus scrofa (pig)
ERibosomal protein eL6polymer23627052.41
Sus scrofa (pig)
FRibosomal protein uL30polymer22526590.91
Sus scrofa (pig)
GRibosomal protein eL8polymer26630167.21
UniProt (I3LVI8)
Pfam (PF01248)
Sus scrofa (pig)
HRibosomal protein uL6polymer19221899.61
UniProt (I3LP78)
Pfam (PF00347)
Sus scrofa (pig)
IRibosomal protein uL16polymer21324465.91
Sus scrofa (pig)
JRibosomal protein uL5polymer17820248.51
UniProt (Q29205)
Pfam (PF00281)
Pfam (PF00673)
Sus scrofa (pig)
KRibosomal protein uL11polymer16317689.61
UniProt (Q6QAS5)
Pfam (PF00298)
Pfam (PF03946)
Sus scrofa (pig)
LRibosomal protein eL13polymer21124366.01
UniProt (I3LSD3)
Pfam (PF01294)
Sus scrofa (pig)
MRibosomal protein eL14polymer21323383.21
UniProt (A1XQU3)
Pfam (PF01929)
Sus scrofa (pig)
NRibosomal protein eL15polymer20424207.51
UniProt (I3LK33)
Pfam (PF00827)
Sus scrofa (pig)
ORibosomal protein uL13polymer20423765.71
UniProt (F1RI01)
Pfam (PF00572)
Sus scrofa (pig)
PRibosomal protein uL22polymer15317757.81
Sus scrofa (pig)
QRibosomal protein eL18polymer18821588.71
UniProt (I3L6F1)
Pfam (PF17135)
Sus scrofa (pig)
RRibosomal protein eL19polymer19623567.41
UniProt (F2Z546)
Pfam (PF01280)
Sus scrofa (pig)
SRibosomal protein eL20polymer22426103.61
UniProt (F1S935)
Pfam (PF01775)
Sus scrofa (pig)
TRibosomal protein eL21polymer16018610.11
UniProt (F1RTJ9)
Pfam (PF01157)
Sus scrofa (pig)
URibosomal protein eL22polymer12814785.11
UniProt (P67985)
Pfam (PF01776)
Sus scrofa (pig)
VRibosomal protein uL14polymer14014892.61
UniProt (P62831)
Pfam (PF00238)
Sus scrofa (pig)
WRibosomal protein eL24polymer15717825.31
Sus scrofa (pig)
XRibosomal protein uL23polymer15617740.41
UniProt (F2Z522)
Pfam (PF00276)
Pfam (PF03939)
Sus scrofa (pig)
YRibosomal protein uL24polymer14517303.51
UniProt (I3L7Y1)
Pfam (PF00467)
Pfam (PF16906)
Sus scrofa (pig)
ZRibosomal protein eL27polymer13615836.01
UniProt (A1XQU5)
Pfam (PF00467)
Pfam (PF01777)
Sus scrofa (pig)
aRibosomal protein uL15polymer14816631.71
UniProt (F1RGC0)
Pfam (PF00828)
Sus scrofa (pig)
bRibosomal protein eL29polymer16017546.01
UniProt (Q95281)
Pfam (PF01779)
Sus scrofa (pig)
cRibosomal protein eL30polymer11512805.21
UniProt (F2Z554)
Pfam (PF01248)
Sus scrofa (pig)
dRibosomal protein eL31polymer12514495.11
UniProt (P62901)
Pfam (PF01198)
Sus scrofa (pig)
eRibosomal protein eL32polymer13515899.11
UniProt (Q6QAT0)
Pfam (PF01655)
Sus scrofa (pig)
fRibosomal protein eL33polymer11012564.81
UniProt (F2Z5Q8)
Pfam (PF01247)
Sus scrofa (pig)
gRibosomal protein eL34polymer11713326.21
UniProt (F2Z5B9)
Pfam (PF01199)
Sus scrofa (pig)
hRibosomal protein uL29polymer12314591.81
UniProt (Q29361)
Pfam (PF00831)
Sus scrofa (pig)
iRibosomal protein eL36polymer10512291.01
UniProt (F2Z5K6)
Pfam (PF01158)
Sus scrofa (pig)
jRibosomal protein eL37polymer8610103.01
Sus scrofa (pig)
kRibosomal protein eL38polymer708239.01
UniProt (F2Z568)
Pfam (PF01781)
Sus scrofa (pig)
lRibosomal protein eL39polymer516426.81
UniProt (K7GP63)
Pfam (PF00832)
Sus scrofa (pig)
mRibosomal protein eL40polymer12814758.51
UniProt (P63053)
Pfam (PF00240)
Pfam (PF01020)
Sus scrofa (pig)
nRibosomal protein eL41polymer253473.51
Sus scrofa (pig)
oRibosomal protein eL42polymer10612477.11
UniProt (P83884)
Pfam (PF00935)
Sus scrofa (pig)
pRibosomal protein eL43polymer9110168.21
Sus scrofa (pig)
qRibosomal protein uL10polymer20222218.01
Sus scrofa (pig)
rRibosomal protein eL28polymer12514301.91
Sus scrofa (pig)
4Eukaryotic elongation factor 2polymer85695233.61
Sus scrofa (pig)
S218S ribosomal RNApolymer1742561960.01
Sus scrofa (pig)
SARibosomal protein uS2polymer29532958.31
UniProt (Q4GWZ2)
Pfam (PF00318)
Pfam (PF16122)
Sus scrofa (pig)
SBRibosomal protein eS1polymer26429932.11
UniProt (B6V8C8)
Pfam (PF01015)
Sus scrofa (pig)
SCRibosomal protein uS5polymer21824091.61
Sus scrofa (pig)
SDRibosomal protein uS3polymer24326729.51
UniProt (Q0Z8U2)
Pfam (PF00189)
Pfam (PF07650)
Sus scrofa (pig)
SERibosomal protein eS4polymer26329655.11
UniProt (F1RQ91)
Pfam (PF00467)
Pfam (PF00900)
Pfam (PF01479)
Pfam (PF08071)
Pfam (PF16121)
Sus scrofa (pig)
SFRibosomal protein uS7polymer20422913.61
UniProt (F2Z5E6)
Pfam (PF00177)
Sus scrofa (pig)
SGRibosomal protein eS6polymer24928752.11
Sus scrofa (pig)
SHRibosomal protein eS7polymer19422169.11
UniProt (I3L5B2)
Pfam (PF01251)
Sus scrofa (pig)
SIRibosomal protein eS8polymer20824263.61
UniProt (F2Z5F5)
Pfam (PF01201)
Sus scrofa (pig)
SJRibosomal protein uS4polymer19422641.81
Sus scrofa (pig)
SKRibosomal protein eS10polymer16518968.01
UniProt (F1RZ28)
Pfam (PF03501)
Sus scrofa (pig)
SLRibosomal protein uS17polymer15818469.01
UniProt (F2Z4Y8)
Pfam (PF00366)
Pfam (PF16205)
Sus scrofa (pig)
SMRibosomal protein eS12polymer12413776.11
Sus scrofa (pig)
SNRibosomal protein uS15polymer15117259.51
Sus scrofa (pig)
SORibosomal protein uS11polymer15116302.91
Sus scrofa (pig)
SPRibosomal protein uS19polymer14517076.31
UniProt (P62844)
Pfam (PF00203)
Sus scrofa (pig)
SQRibosomal protein uS9polymer14616477.51
UniProt (Q29201)
Pfam (PF00380)
Sus scrofa (pig)
SRRibosomal protein eS17polymer13515552.31
UniProt (Q6QAP7)
Pfam (PF00833)
Sus scrofa (pig)
SSRibosomal protein uS13polymer15217759.91
UniProt (P62272)
Pfam (PF00416)
Sus scrofa (pig)
STRibosomal protein eS19polymer14516091.71
UniProt (F1RGG1)
Pfam (PF01090)
Sus scrofa (pig)
SURibosomal protein uS10polymer11913357.81
UniProt (A1XQU9)
Pfam (PF00338)
Sus scrofa (pig)
SVRibosomal protein eS21polymer839124.51
UniProt (P63221)
Pfam (PF01249)
Sus scrofa (pig)
SWRibosomal protein uS8polymer13014865.71
Sus scrofa (pig)
SXRibosomal protein uS12polymer14315854.81
UniProt (Q6SA96)
Pfam (PF00164)
Sus scrofa (pig)
SYRibosomal protein eS24polymer13215366.41
Sus scrofa (pig)
SZRibosomal protein es25polymer12513776.41
Sus scrofa (pig)
SaRibosomal protein eS26polymer11513047.61
UniProt (P49171)
Pfam (PF01283)
Sus scrofa (pig)
SbRibosomal protein eS27polymer849480.21
Sus scrofa (pig)
ScRibosomal protein eS28polymer697855.11
UniProt (Q6QAT1)
Pfam (PF01200)
Sus scrofa (pig)
SdRibosomal protein uS14polymer566612.81
UniProt (Q6QAP6)
Pfam (PF00253)
Sus scrofa (pig)
SeRibosomal protein eS30polymer13314411.91
Sus scrofa (pig)
SfRibosomal protein eS31polymer15618004.21
UniProt (F2Z5U0)
Pfam (PF00240)
Pfam (PF01599)
Sus scrofa (pig)
SgRibosomal protein RACK1polymer31735115.91
UniProt (P63246)
Pfam (PF00400)
Sus scrofa (pig)
ZINC IONnon-polymer65.44
MAGNESIUM IONnon-polymer24.3166

Sequence viewer

Contents of the asymmetric unit

PolymersNumber of chains82
Total molecular weight3403040.3
Non-Polymers*Number of molecules170
Total molecular weight4296.2
All*Total molecular weight3407336.5
*Water molecules are not included.

> Experimental details

Refinement Statistics

Experimental method:ELECTRON MICROSCOPY

Cell axes1.0001.0001.000
Cell angles90.0090.0090.00
SpacegroupP 1
Resolution limits -
the highest resolution shell value -

Data Collection Statistics

Resolution limits -
the highest resolution shell value -

Crystallization Conditions

crystal IDmethodpHpH rangetemperatureunit

Crystallization Reagents

IDcrystal IDsolution IDreagent nameconcentrationdetails
Crystallization Reagents in Literatures*
IDcrystal IDsolutionreagent nameconcentration (unit)details
Annotated Information is extracted from Literature Info*

> Functional details

?

Functional Information from GO Data

ChainGOidnamespacecontents
Sg0005737cellular_componentcytoplasm
Sg0030425cellular_componentdendrite
Sg0030496cellular_componentmidbody
Sg0043025cellular_componentneuronal cell body
Sg0005634cellular_componentnucleus
Sg0043204cellular_componentperikaryon
Sg0048471cellular_componentperinuclear region of cytoplasm
Sg0001891cellular_componentphagocytic cup
Sg0005080molecular_functionprotein kinase C binding
Sg0030292molecular_functionprotein tyrosine kinase inhibitor activity
Sg0030971molecular_functionreceptor tyrosine kinase binding
Sg0042169molecular_functionSH2 domain binding
Sg0006915biological_processapoptotic process
Sg0007049biological_processcell cycle
Sg0071363biological_processcellular response to growth factor stimulus
Sg0007369biological_processgastrulation
Sg0030308biological_processnegative regulation of cell growth
Sg0050765biological_processnegative regulation of phagocytosis
Sg0030178biological_processnegative regulation of Wnt signaling pathway
Sg0043065biological_processpositive regulation of apoptotic process
Sg0030335biological_processpositive regulation of cell migration
Sg2000543biological_processpositive regulation of gastrulation
Sg0042998biological_processpositive regulation of Golgi to plasma membrane protein transport
Sg0043547biological_processpositive regulation of GTPase activity
Sg0032436biological_processpositive regulation of proteasomal ubiquitin-dependent protein catabolic process
Sg0032464biological_processpositive regulation of protein homooligomerization
Sg0001934biological_processpositive regulation of protein phosphorylation
Sg0051726biological_processregulation of cell cycle
Sg0051302biological_processregulation of cell division
Sg2000114biological_processregulation of establishment of cell polarity
Sg0032880biological_processregulation of protein localization
Sg0006417biological_processregulation of translation
Sg0048511biological_processrhythmic process
I0022625cellular_componentcytosolic large ribosomal subunit
I0003735molecular_functionstructural constituent of ribosome
I0000027biological_processribosomal large subunit assembly
I0006412biological_processtranslation
J0022625cellular_componentcytosolic large ribosomal subunit
J0005730cellular_componentnucleolus
J0005654cellular_componentnucleoplasm
J0019843molecular_functionrRNA binding
J0003735molecular_functionstructural constituent of ribosome
J0034504biological_processprotein localization to nucleus
J0000027biological_processribosomal large subunit assembly
J0006412biological_processtranslation
M0005840cellular_componentribosome
M0003735molecular_functionstructural constituent of ribosome
M0006412biological_processtranslation
U0022625cellular_componentcytosolic large ribosomal subunit
U0008201molecular_functionheparin binding
U0003723molecular_functionRNA binding
U0003735molecular_functionstructural constituent of ribosome
U0046632biological_processalpha-beta T cell differentiation
U0002181biological_processcytoplasmic translation
V0022625cellular_componentcytosolic large ribosomal subunit
V0070062cellular_componentextracellular exosome
V0031012cellular_componentextracellular matrix
V0005925cellular_componentfocal adhesion
V0016020cellular_componentmembrane
V0005730cellular_componentnucleolus
V0070180molecular_functionlarge ribosomal subunit rRNA binding
V0003735molecular_functionstructural constituent of ribosome
V0006412biological_processtranslation
Z0022625cellular_componentcytosolic large ribosomal subunit
Z0003735molecular_functionstructural constituent of ribosome
Z0006412biological_processtranslation
b0022625cellular_componentcytosolic large ribosomal subunit
b0016020cellular_componentmembrane
b0003723molecular_functionRNA binding
b0003735molecular_functionstructural constituent of ribosome
b0002181biological_processcytoplasmic translation
d0005840cellular_componentribosome
d0003735molecular_functionstructural constituent of ribosome
d0006412biological_processtranslation
e0022625cellular_componentcytosolic large ribosomal subunit
e0016020cellular_componentmembrane
e0003723molecular_functionRNA binding
e0003735molecular_functionstructural constituent of ribosome
e0006412biological_processtranslation
h0022625cellular_componentcytosolic large ribosomal subunit
h0016020cellular_componentmembrane
h0003729molecular_functionmRNA binding
h0003735molecular_functionstructural constituent of ribosome
h0000463biological_processmaturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
h0006412biological_processtranslation
o0022625cellular_componentcytosolic large ribosomal subunit
o0003735molecular_functionstructural constituent of ribosome
o0006412biological_processtranslation
m0005829cellular_componentcytosol
m0005783cellular_componentendoplasmic reticulum
m0070062cellular_componentextracellular exosome
m0005615cellular_componentextracellular space
m0005765cellular_componentlysosomal membrane
m0043209cellular_componentmyelin sheath
m0005654cellular_componentnucleoplasm
m0005886cellular_componentplasma membrane
m0005840cellular_componentribosome
m0003735molecular_functionstructural constituent of ribosome
m0006412biological_processtranslation
E0036464cellular_componentcytoplasmic ribonucleoprotein granule
E0022625cellular_componentcytosolic large ribosomal subunit
E0005925cellular_componentfocal adhesion
E0016020cellular_componentmembrane
E0005634cellular_componentnucleus
E0003723molecular_functionRNA binding
E0003735molecular_functionstructural constituent of ribosome
E0002181biological_processcytoplasmic translation
E0000027biological_processribosomal large subunit assembly
q0005737cellular_componentcytoplasm
q0030529cellular_componentintracellular ribonucleoprotein complex
q0005634cellular_componentnucleus
q0005840cellular_componentribosome
q0042254biological_processribosome biogenesis
SP0022627cellular_componentcytosolic small ribosomal subunit
SP0003723molecular_functionRNA binding
SP0003735molecular_functionstructural constituent of ribosome
SP0000028biological_processribosomal small subunit assembly
SP0006412biological_processtranslation
SQ0022627cellular_componentcytosolic small ribosomal subunit
SQ0015935cellular_componentsmall ribosomal subunit
SQ0003735molecular_functionstructural constituent of ribosome
SQ0000462biological_processmaturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SQ0006412biological_processtranslation
SR0022627cellular_componentcytosolic small ribosomal subunit
SR0003735molecular_functionstructural constituent of ribosome
SR0000028biological_processribosomal small subunit assembly
SR0006412biological_processtranslation
SS0005829cellular_componentcytosol
SS0022627cellular_componentcytosolic small ribosomal subunit
SS0070062cellular_componentextracellular exosome
SS0031012cellular_componentextracellular matrix
SS0005925cellular_componentfocal adhesion
SS0016020cellular_componentmembrane
SS0005634cellular_componentnucleus
SS0015935cellular_componentsmall ribosomal subunit
SS0019843molecular_functionrRNA binding
SS0003735molecular_functionstructural constituent of ribosome
SS0042254biological_processribosome biogenesis
SS0006412biological_processtranslation
SU0022627cellular_componentcytosolic small ribosomal subunit
SU0003723molecular_functionRNA binding
SU0003735molecular_functionstructural constituent of ribosome
SU0006412biological_processtranslation
SV0022627cellular_componentcytosolic small ribosomal subunit
SV0043022molecular_functionribosome binding
SV0003735molecular_functionstructural constituent of ribosome
SV0000447biological_processendonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SV0000461biological_processendonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SV0006412biological_processtranslation
SX0022627cellular_componentcytosolic small ribosomal subunit
SX0003735molecular_functionstructural constituent of ribosome
SX0006412biological_processtranslation
Sa0022627cellular_componentcytosolic small ribosomal subunit
Sa0003729molecular_functionmRNA binding
Sa0003735molecular_functionstructural constituent of ribosome
Sa0006412biological_processtranslation
Sc0022627cellular_componentcytosolic small ribosomal subunit
Sc0070062cellular_componentextracellular exosome
Sc0003723molecular_functionRNA binding
Sc0003735molecular_functionstructural constituent of ribosome
Sc0030490biological_processmaturation of SSU-rRNA
Sc0000028biological_processribosomal small subunit assembly
Sc0042254biological_processribosome biogenesis
Sc0006412biological_processtranslation
Sd0022627cellular_componentcytosolic small ribosomal subunit
Sd0003735molecular_functionstructural constituent of ribosome
Sd0008270molecular_functionzinc ion binding
Sd0006412biological_processtranslation
SD0022627cellular_componentcytosolic small ribosomal subunit
SD0030529cellular_componentintracellular ribonucleoprotein complex
SD0005743cellular_componentmitochondrial inner membrane
SD0005730cellular_componentnucleolus
SD0005634cellular_componentnucleus
SD0005819cellular_componentspindle
SD0003684molecular_functiondamaged DNA binding
SD0008534molecular_functionoxidized purine nucleobase lesion DNA N-glycosylase activity
SD0003723molecular_functionRNA binding
SD0003735molecular_functionstructural constituent of ribosome
SD0006915biological_processapoptotic process
SD0051301biological_processcell division
SD0006281biological_processDNA repair
SD0007067biological_processmitotic nuclear division
SD0006355biological_processregulation of transcription, DNA-templated
SD0006417biological_processregulation of translation
SD0006351biological_processtranscription, DNA-templated
SD0006412biological_processtranslation
SA0030686cellular_component90S preribosome
SA0022627cellular_componentcytosolic small ribosomal subunit
SA0005634cellular_componentnucleus
SA0005886cellular_componentplasma membrane
SA0005055molecular_functionlaminin receptor activity
SA0003735molecular_functionstructural constituent of ribosome
SA0001618molecular_functionvirus receptor activity
SA0000447biological_processendonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SA0000461biological_processendonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SA0000028biological_processribosomal small subunit assembly
SA0006407biological_processrRNA export from nucleus
SA0006412biological_processtranslation
X0022625cellular_componentcytosolic large ribosomal subunit
X0000166molecular_functionnucleotide binding
X0003735molecular_functionstructural constituent of ribosome
X0000027biological_processribosomal large subunit assembly
X0006412biological_processtranslation
f0022625cellular_componentcytosolic large ribosomal subunit
f0070062cellular_componentextracellular exosome
f0031012cellular_componentextracellular matrix
f0016020cellular_componentmembrane
f0003723molecular_functionRNA binding
f0003735molecular_functionstructural constituent of ribosome
f0042273biological_processribosomal large subunit biogenesis
f0006364biological_processrRNA processing
f0006412biological_processtranslation
K0022625cellular_componentcytosolic large ribosomal subunit
K0070062cellular_componentextracellular exosome
K0031012cellular_componentextracellular matrix
K0005925cellular_componentfocal adhesion
K0016020cellular_componentmembrane
K0005730cellular_componentnucleolus
K0019843molecular_functionrRNA binding
K0003735molecular_functionstructural constituent of ribosome
K0000027biological_processribosomal large subunit assembly
K0006412biological_processtranslation
T0005840cellular_componentribosome
T0003735molecular_functionstructural constituent of ribosome
T0006412biological_processtranslation
SB0022627cellular_componentcytosolic small ribosomal subunit
SB0005634cellular_componentnucleus
SB0003735molecular_functionstructural constituent of ribosome
SB0030154biological_processcell differentiation
SB0006412biological_processtranslation
Sf0022627cellular_componentcytosolic small ribosomal subunit
Sf0070062cellular_componentextracellular exosome
Sf0005615cellular_componentextracellular space
Sf0016020cellular_componentmembrane
Sf0043209cellular_componentmyelin sheath
Sf0005730cellular_componentnucleolus
Sf0003723molecular_functionRNA binding
Sf0003735molecular_functionstructural constituent of ribosome
Sf0006412biological_processtranslation
Y0022625cellular_componentcytosolic large ribosomal subunit
Y0070062cellular_componentextracellular exosome
Y0016020cellular_componentmembrane
Y0003723molecular_functionRNA binding
Y0003735molecular_functionstructural constituent of ribosome
Y0042273biological_processribosomal large subunit biogenesis
Y0006364biological_processrRNA processing
Y0006412biological_processtranslation
SI0022627cellular_componentcytosolic small ribosomal subunit
SI0005783cellular_componentendoplasmic reticulum
SI0070062cellular_componentextracellular exosome
SI0005925cellular_componentfocal adhesion
SI0016020cellular_componentmembrane
SI0005634cellular_componentnucleus
SI0003723molecular_functionRNA binding
SI0003735molecular_functionstructural constituent of ribosome
SI0000462biological_processmaturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SI0006412biological_processtranslation
ST0022627cellular_componentcytosolic small ribosomal subunit
ST0003735molecular_functionstructural constituent of ribosome
ST0007219biological_processNotch signaling pathway
ST0000028biological_processribosomal small subunit assembly
ST0006412biological_processtranslation
H0022625cellular_componentcytosolic large ribosomal subunit
H0031012cellular_componentextracellular matrix
H0005925cellular_componentfocal adhesion
H0016020cellular_componentmembrane
H0005634cellular_componentnucleus
H0003723molecular_functionRNA binding
H0019843molecular_functionrRNA binding
H0003735molecular_functionstructural constituent of ribosome
H0002181biological_processcytoplasmic translation
SK0022627cellular_componentcytosolic small ribosomal subunit
SK0003735molecular_functionstructural constituent of ribosome
SK0000028biological_processribosomal small subunit assembly
SF0022627cellular_componentcytosolic small ribosomal subunit
SF0070062cellular_componentextracellular exosome
SF0031012cellular_componentextracellular matrix
SF0005925cellular_componentfocal adhesion
SF0016020cellular_componentmembrane
SF0003729molecular_functionmRNA binding
SF0003735molecular_functionstructural constituent of ribosome
SF0006450biological_processregulation of translational fidelity
SF0006412biological_processtranslation
A0022625cellular_componentcytosolic large ribosomal subunit
A0005925cellular_componentfocal adhesion
A0016020cellular_componentmembrane
A0003723molecular_functionRNA binding
A0003735molecular_functionstructural constituent of ribosome
A0002181biological_processcytoplasmic translation
L0022625cellular_componentcytosolic large ribosomal subunit
L0016020cellular_componentmembrane
L0005634cellular_componentnucleus
L0003723molecular_functionRNA binding
L0003735molecular_functionstructural constituent of ribosome
L0006412biological_processtranslation
SH0005840cellular_componentribosome
SH0003735molecular_functionstructural constituent of ribosome
SH0006412biological_processtranslation
i0022625cellular_componentcytosolic large ribosomal subunit
i0016020cellular_componentmembrane
i0005730cellular_componentnucleolus
i0003723molecular_functionRNA binding
i0003735molecular_functionstructural constituent of ribosome
i0002181biological_processcytoplasmic translation
SL0022627cellular_componentcytosolic small ribosomal subunit
SL0070062cellular_componentextracellular exosome
SL0031012cellular_componentextracellular matrix
SL0005925cellular_componentfocal adhesion
SL0016020cellular_componentmembrane
SL0005730cellular_componentnucleolus
SL0003723molecular_functionRNA binding
SL0003735molecular_functionstructural constituent of ribosome
SL0006412biological_processtranslation
g0022625cellular_componentcytosolic large ribosomal subunit
g0070062cellular_componentextracellular exosome
g0005739cellular_componentmitochondrion
g0003735molecular_functionstructural constituent of ribosome
g0006412biological_processtranslation
O0015934cellular_componentlarge ribosomal subunit
O0003735molecular_functionstructural constituent of ribosome
O0006412biological_processtranslation
a0022625cellular_componentcytosolic large ribosomal subunit
a0003735molecular_functionstructural constituent of ribosome
a0006412biological_processtranslation
R0022625cellular_componentcytosolic large ribosomal subunit
R0005925cellular_componentfocal adhesion
R0016020cellular_componentmembrane
R0003723molecular_functionRNA binding
R0003735molecular_functionstructural constituent of ribosome
R0006412biological_processtranslation
SE0036464cellular_componentcytoplasmic ribonucleoprotein granule
SE0022627cellular_componentcytosolic small ribosomal subunit
SE0070062cellular_componentextracellular exosome
SE0031012cellular_componentextracellular matrix
SE0005925cellular_componentfocal adhesion
SE0016020cellular_componentmembrane
SE0005844cellular_componentpolysome
SE0019843molecular_functionrRNA binding
SE0003735molecular_functionstructural constituent of ribosome
SE0007275biological_processmulticellular organism development
SE0008284biological_processpositive regulation of cell proliferation
SE0045727biological_processpositive regulation of translation
SE0006412biological_processtranslation
c0022625cellular_componentcytosolic large ribosomal subunit
c0070062cellular_componentextracellular exosome
c0031012cellular_componentextracellular matrix
c0005925cellular_componentfocal adhesion
c0016020cellular_componentmembrane
c0005634cellular_componentnucleus
c0003723molecular_functionRNA binding
c0003735molecular_functionstructural constituent of ribosome
c0006412biological_processtranslation
S0022625cellular_componentcytosolic large ribosomal subunit
S0016020cellular_componentmembrane
S0003723molecular_functionRNA binding
S0003735molecular_functionstructural constituent of ribosome
S0006412biological_processtranslation
k0022625cellular_componentcytosolic large ribosomal subunit
k0033291cellular_componenteukaryotic 80S initiation complex
k0005925cellular_componentfocal adhesion
k0003735molecular_functionstructural constituent of ribosome
k0034463biological_process90S preribosome assembly
k0048318biological_processaxial mesoderm development
k0042474biological_processmiddle ear morphogenesis
k0001503biological_processossification
k0006417biological_processregulation of translation
k0007605biological_processsensory perception of sound
k0001501biological_processskeletal system development
k0006412biological_processtranslation
Q0022625cellular_componentcytosolic large ribosomal subunit
Q0005783cellular_componentendoplasmic reticulum
Q0005925cellular_componentfocal adhesion
Q0016020cellular_componentmembrane
Q0005730cellular_componentnucleolus
Q0003735molecular_functionstructural constituent of ribosome
Q0006412biological_processtranslation
l0005840cellular_componentribosome
l0003735molecular_functionstructural constituent of ribosome
l0006412biological_processtranslation
N0022625cellular_componentcytosolic large ribosomal subunit
N0003735molecular_functionstructural constituent of ribosome
N0002181biological_processcytoplasmic translation
G0030529cellular_componentintracellular ribonucleoprotein complex
G0042254biological_processribosome biogenesis
D0005840cellular_componentribosome
D0008097molecular_function5S rRNA binding
D0003735molecular_functionstructural constituent of ribosome
D0006412biological_processtranslation
?

Functional Information from PDB Data

site_idNumber of ResiduesDetails
AC14BINDING SITE FOR RESIDUE MG 5 5101
ChainResidue
5G2584
gGLY55
gTHR70
gHIS73

AC22BINDING SITE FOR RESIDUE MG 5 5102
ChainResidue
5A39
5U3915

AC34BINDING SITE FOR RESIDUE MG 5 5103
ChainResidue
5U37
5A38
5G40
5C41

AC43BINDING SITE FOR RESIDUE MG 5 5104
ChainResidue
5U43
5A44
5U45

AC52BINDING SITE FOR RESIDUE MG 5 5105
ChainResidue
5A47
5G48

AC61BINDING SITE FOR RESIDUE MG 5 5106
ChainResidue
5A51

AC72BINDING SITE FOR RESIDUE MG 5 5107
ChainResidue
5G21
5A56

AC82BINDING SITE FOR RESIDUE MG 5 5108
ChainResidue
5A61
5G63

AC92BINDING SITE FOR RESIDUE MG 5 5109
ChainResidue
5A62
5U333

BC14BINDING SITE FOR RESIDUE MG 5 5110
ChainResidue
5A84
5G85
5G1383
5C1384

BC21BINDING SITE FOR RESIDUE MG 5 5112
ChainResidue
5A105

BC32BINDING SITE FOR RESIDUE MG 5 5113
ChainResidue
5C112
5G156

BC41BINDING SITE FOR RESIDUE MG 5 5114
ChainResidue
5G114

BC52BINDING SITE FOR RESIDUE MG 5 5115
ChainResidue
5A198
5G240

BC61BINDING SITE FOR RESIDUE MG 5 5116
ChainResidue
5A235

BC72BINDING SITE FOR RESIDUE MG 5 5117
ChainResidue
5U231
5A235

BC81BINDING SITE FOR RESIDUE MG 5 5118
ChainResidue
5C282

BC92BINDING SITE FOR RESIDUE MG 5 5119
ChainResidue
5G288
5A4178

CC11BINDING SITE FOR RESIDUE MG 5 5120
ChainResidue
5U291

CC22BINDING SITE FOR RESIDUE MG 5 5121
ChainResidue
5A47
5U291

CC32BINDING SITE FOR RESIDUE MG 5 5122
ChainResidue
5U316
5U4354

CC42BINDING SITE FOR RESIDUE MG 5 5124
ChainResidue
5C351
5G2343

CC53BINDING SITE FOR RESIDUE MG 5 5126
ChainResidue
5G356
5C358
CGLY98

CC63BINDING SITE FOR RESIDUE MG 5 5127
ChainResidue
5A355
5G356
5A359

CC71BINDING SITE FOR RESIDUE MG 5 5128
ChainResidue
5A2332

CC83BINDING SITE FOR RESIDUE MG 5 5129
ChainResidue
5A407
5G2330
5G2331

CC94BINDING SITE FOR RESIDUE MG 5 5130
ChainResidue
5A410
5G415
5U416
5G2331

DC13BINDING SITE FOR RESIDUE MG 5 5131
ChainResidue
5G415
5U416
5G417

DC25BINDING SITE FOR RESIDUE MG 5 5132
ChainResidue
5C422
5G423
5U424
8A9
8G10

DC33BINDING SITE FOR RESIDUE MG 5 5134
ChainResidue
5C1665
5A2279
5G2280

DC41BINDING SITE FOR RESIDUE MG 5 5135
ChainResidue
5A2282

DC52BINDING SITE FOR RESIDUE MG 5 5136
ChainResidue
5A2367
5U2828

DC63BINDING SITE FOR RESIDUE MG 5 5137
ChainResidue
5A2368
5A2370
5U2826

DC71BINDING SITE FOR RESIDUE MG 5 5138
ChainResidue
5C2393

DC81BINDING SITE FOR RESIDUE MG 5 5139
ChainResidue
5A2401

DC93BINDING SITE FOR RESIDUE MG 5 5140
ChainResidue
5C2410
5C2411
5A2428

EC12BINDING SITE FOR RESIDUE MG 5 5141
ChainResidue
5C2422
5A2423

EC21BINDING SITE FOR RESIDUE MG 5 5142
ChainResidue
5G2510

EC32BINDING SITE FOR RESIDUE MG 5 5143
ChainResidue
5G2514
5G2516

EC41BINDING SITE FOR RESIDUE MG 5 5144
ChainResidue
5G2677

EC53BINDING SITE FOR RESIDUE MG 5 5145
ChainResidue
5G2402
5A2783
5C2784

EC63BINDING SITE FOR RESIDUE MG 5 5146
ChainResidue
5A2789
5G2827
5U2828

EC71BINDING SITE FOR RESIDUE MG 5 5147
ChainResidue
5C2792

EC84BINDING SITE FOR RESIDUE MG 5 5148
ChainResidue
5A1599
5A1600
5G2793
5C2794

EC91BINDING SITE FOR RESIDUE MG 5 5149
ChainResidue
5A2845

FC11BINDING SITE FOR RESIDUE MG 5 5150
ChainResidue
5A2857

FC22BINDING SITE FOR RESIDUE MG 5 5151
ChainResidue
5A2879
5A3629

FC31BINDING SITE FOR RESIDUE MG 5 5152
ChainResidue
5C3632

FC42BINDING SITE FOR RESIDUE MG 5 5153
ChainResidue
5G3634
5C3636

FC53BINDING SITE FOR RESIDUE MG 5 5154
ChainResidue
5A3642
5U3644
5U3645

FC64BINDING SITE FOR RESIDUE MG 5 5155
ChainResidue
5C3701
5U3704
5G3705
5U3745

FC74BINDING SITE FOR RESIDUE MG 5 5156
ChainResidue
5G3689
5A3747
5A3748
5U3818

FC81BINDING SITE FOR RESIDUE MG 5 5158
ChainResidue
5U3778

FC91BINDING SITE FOR RESIDUE MG 5 5159
ChainResidue
5A3783

GC11BINDING SITE FOR RESIDUE MG 5 5160
ChainResidue
5A3817

GC22BINDING SITE FOR RESIDUE MG 5 5161
ChainResidue
5A2363
5U3853

GC36BINDING SITE FOR RESIDUE MG 5 5162
ChainResidue
5A1324
5C1325
5G3875
5A3876
5A3877
5G3879

GC43BINDING SITE FOR RESIDUE MG 5 5163
ChainResidue
5C1678
5G3913
5U3914

GC53BINDING SITE FOR RESIDUE MG 5 5164
ChainResidue
5U3912
5C4193
5U4194

GC64BINDING SITE FOR RESIDUE MG 5 5165
ChainResidue
5G40
5C41
5U3915
5G3916

GC71BINDING SITE FOR RESIDUE MG 5 5166
ChainResidue
5A3917

GC83BINDING SITE FOR RESIDUE MG 5 5168
ChainResidue
5U3920
5G4184
APRO206

GC92BINDING SITE FOR RESIDUE MG 5 5169
ChainResidue
5A3923
5C3924

HC12BINDING SITE FOR RESIDUE MG 5 5170
ChainResidue
5U35
5U4188

HC22BINDING SITE FOR RESIDUE MG 5 5171
ChainResidue
5G1734
5U1735

HC32BINDING SITE FOR RESIDUE MG 5 5172
ChainResidue
5A4214
5C4215

HC42BINDING SITE FOR RESIDUE MG 5 5173
ChainResidue
5G4235
5C4332

HC51BINDING SITE FOR RESIDUE MG 5 5174
ChainResidue
5A4239

HC62BINDING SITE FOR RESIDUE MG 5 5175
ChainResidue
5A4281
DTYR31

HC71BINDING SITE FOR RESIDUE MG 5 5177
ChainResidue
5A4385

HC83BINDING SITE FOR RESIDUE MG 5 5178
ChainResidue
5G1633
5G1641
5G4534

HC95BINDING SITE FOR RESIDUE MG 5 5179
ChainResidue
5A1632
5G1633
5A4535
AALA203
AASN205

IC11BINDING SITE FOR RESIDUE MG 5 5180
ChainResidue
5A4533

IC23BINDING SITE FOR RESIDUE MG 5 5181
ChainResidue
5U1656
5G4392
5G4448

IC35BINDING SITE FOR RESIDUE MG 5 5182
ChainResidue
5G4393
5A4394
5C4443
5C4444
5U4445

IC43BINDING SITE FOR RESIDUE MG 5 5183
ChainResidue
5G1321
5A4394
5U4445

IC51BINDING SITE FOR RESIDUE MG 5 5184
ChainResidue
5G4401

IC61BINDING SITE FOR RESIDUE MG 5 5185
ChainResidue
5C4417

IC71BINDING SITE FOR RESIDUE MG 5 5186
ChainResidue
5A1871

IC83BINDING SITE FOR RESIDUE MG 5 5187
ChainResidue
5A3901
5A3902
5G4451

IC92BINDING SITE FOR RESIDUE MG 5 5188
ChainResidue
5A3902
5G4451

JC12BINDING SITE FOR RESIDUE MG 5 5189
ChainResidue
5A4479
5A4480

JC22BINDING SITE FOR RESIDUE MG 5 5190
ChainResidue
5G2851
5U2852

JC34BINDING SITE FOR RESIDUE MG 5 5191
ChainResidue
5A2850
5G2851
5U2852
5A4496

JC42BINDING SITE FOR RESIDUE MG 5 5192
ChainResidue
5C3833
5U4497

JC53BINDING SITE FOR RESIDUE MG 5 5193
ChainResidue
5G4451
5G4522
5U4557

JC63BINDING SITE FOR RESIDUE MG 5 5194
ChainResidue
5C4519
5G4520
5U4521

JC71BINDING SITE FOR RESIDUE MG 5 5196
ChainResidue
5A4464

JC84BINDING SITE FOR RESIDUE MG 5 5197
ChainResidue
5G3899
5U4521
5G4522
5A4523

JC92BINDING SITE FOR RESIDUE MG 5 5198
ChainResidue
5G1592
5U4526

KC12BINDING SITE FOR RESIDUE MG 5 5199
ChainResidue
5G4528
5G4529

KC22BINDING SITE FOR RESIDUE MG 5 5200
ChainResidue
5G3815
5G4538

KC33BINDING SITE FOR RESIDUE MG 5 5201
ChainResidue
5U1591
5G1592
5U4556

KC41BINDING SITE FOR RESIDUE MG 5 5202
ChainResidue
5G1595

KC51BINDING SITE FOR RESIDUE MG 5 5203
ChainResidue
5U4682

KC61BINDING SITE FOR RESIDUE MG 5 5204
ChainResidue
5A4705

KC72BINDING SITE FOR RESIDUE MG 5 5206
ChainResidue
5G4650
5A4651

KC84BINDING SITE FOR RESIDUE MG 5 5207
ChainResidue
5G4751
5U4752
5U4946
5C4948

KC91BINDING SITE FOR RESIDUE MG 5 5208
ChainResidue
5G1895

LC12BINDING SITE FOR RESIDUE MG 5 5209
ChainResidue
5C1318
5U1656

LC21BINDING SITE FOR RESIDUE MG 5 5210
ChainResidue
5G1680

LC32BINDING SITE FOR RESIDUE MG 5 5211
ChainResidue
5C1318
5U1659

LC43BINDING SITE FOR RESIDUE MG 5 5212
ChainResidue
5C322
5G4355
5G4356

LC51BINDING SITE FOR RESIDUE MG 5 5213
ChainResidue
5U416

LC63BINDING SITE FOR RESIDUE MG 5 5214
ChainResidue
5U354
5A378
5MG5215

LC75BINDING SITE FOR RESIDUE MG 5 5215
ChainResidue
5A353
5U354
5A378
5G379
5MG5214

LC82BINDING SITE FOR RESIDUE MG 5 5216
ChainResidue
5U380
5G415

LC92BINDING SITE FOR RESIDUE MG 5 5217
ChainResidue
5G1335
5C2346

MC12BINDING SITE FOR RESIDUE MG 5 5218
ChainResidue
5A4665
BLYS373

MC21BINDING SITE FOR RESIDUE MG 7 201
ChainResidue
7A42

MC33BINDING SITE FOR RESIDUE MG 7 202
ChainResidue
7U53
7A54
7A55

MC43BINDING SITE FOR RESIDUE MG 7 203
ChainResidue
7U53
7A55
7G56

MC51BINDING SITE FOR RESIDUE MG 7 204
ChainResidue
7G65

MC62BINDING SITE FOR RESIDUE MG 7 205
ChainResidue
5G1895
7A83

MC71BINDING SITE FOR RESIDUE MG 8 202
ChainResidue
8U14

MC81BINDING SITE FOR RESIDUE MG 8 203
ChainResidue
8A20

MC91BINDING SITE FOR RESIDUE MG 8 204
ChainResidue
8G151

NC11BINDING SITE FOR RESIDUE MG P 201
ChainResidue
PTYR130

NC21BINDING SITE FOR RESIDUE MG V 201
ChainResidue
VASN50

NC34BINDING SITE FOR RESIDUE ZN j 101
ChainResidue
jCYS19
jCYS22
jCYS34
jCYS37

NC44BINDING SITE FOR RESIDUE ZN m 201
ChainResidue
mCYS96
mCYS99
mCYS110
mCYS115

NC55BINDING SITE FOR RESIDUE ZN o 201
ChainResidue
oCYS12
oCYS15
oCYS72
oCYS77
oSER79

NC61BINDING SITE FOR RESIDUE MG 4 901
ChainResidue
4ASP29

?

Functional Information from PDB atom coordinates for the "HETATM" binding sites

site_idNumber of ResiduesDetails
?

Functional Information from PROSITE/UniProt

site_idNumber of ResiduesDetails
?

Functional Information from SwissProt/UniProt

site_idNumber of ResiduesDetails
SWS_FT_FI22Activating enzyme.
ChainResidueDetails
mNA*
mNA*

?

Catalytic Information from CSA

site_idNumber of ResiduesDetails

> Sequence Neighbor

Sequence navigator - 3j7p: Chain 5
Sequence navigator - 3j7p: Chain 7
Sequence navigator - 3j7p: Chain 8
Sequence navigator - 3j7p: Chain A
Sequence navigator - 3j7p: Chain B
Sequence navigator - 3j7p: Chain C
Sequence navigator - 3j7p: Chain D
Sequence navigator - 3j7p: Chain E
Sequence navigator - 3j7p: Chain F
Sequence navigator - 3j7p: Chain G
Sequence navigator - 3j7p: Chain H
Sequence navigator - 3j7p: Chain I
Sequence navigator - 3j7p: Chain J
Sequence navigator - 3j7p: Chain K
Sequence navigator - 3j7p: Chain L
Sequence navigator - 3j7p: Chain M
Sequence navigator - 3j7p: Chain N
Sequence navigator - 3j7p: Chain O
Sequence navigator - 3j7p: Chain P
Sequence navigator - 3j7p: Chain Q
Sequence navigator - 3j7p: Chain R
Sequence navigator - 3j7p: Chain S
Sequence navigator - 3j7p: Chain T
Sequence navigator - 3j7p: Chain U
Sequence navigator - 3j7p: Chain V
Sequence navigator - 3j7p: Chain W
Sequence navigator - 3j7p: Chain X
Sequence navigator - 3j7p: Chain Y
Sequence navigator - 3j7p: Chain Z
Sequence navigator - 3j7p: Chain a
Sequence navigator - 3j7p: Chain b
Sequence navigator - 3j7p: Chain c
Sequence navigator - 3j7p: Chain d
Sequence navigator - 3j7p: Chain e
Sequence navigator - 3j7p: Chain f
Sequence navigator - 3j7p: Chain g
Sequence navigator - 3j7p: Chain h
Sequence navigator - 3j7p: Chain i
Sequence navigator - 3j7p: Chain j
Sequence navigator - 3j7p: Chain k
Sequence navigator - 3j7p: Chain l
Sequence navigator - 3j7p: Chain m
Sequence navigator - 3j7p: Chain n
Sequence navigator - 3j7p: Chain o
Sequence navigator - 3j7p: Chain p
Sequence navigator - 3j7p: Chain q
Sequence navigator - 3j7p: Chain r
Sequence navigator - 3j7p: Chain 4
Sequence navigator - 3j7p: Chain S2
Sequence navigator - 3j7p: Chain SA
Sequence navigator - 3j7p: Chain SB
Sequence navigator - 3j7p: Chain SC
Sequence navigator - 3j7p: Chain SD
Sequence navigator - 3j7p: Chain SE
Sequence navigator - 3j7p: Chain SF
Sequence navigator - 3j7p: Chain SG
Sequence navigator - 3j7p: Chain SH
Sequence navigator - 3j7p: Chain SI
Sequence navigator - 3j7p: Chain SJ
Sequence navigator - 3j7p: Chain SK
Sequence navigator - 3j7p: Chain SL
Sequence navigator - 3j7p: Chain SM
Sequence navigator - 3j7p: Chain SN
Sequence navigator - 3j7p: Chain SO
Sequence navigator - 3j7p: Chain SP
Sequence navigator - 3j7p: Chain SQ
Sequence navigator - 3j7p: Chain SR
Sequence navigator - 3j7p: Chain SS
Sequence navigator - 3j7p: Chain ST
Sequence navigator - 3j7p: Chain SU
Sequence navigator - 3j7p: Chain SV
Sequence navigator - 3j7p: Chain SW
Sequence navigator - 3j7p: Chain SX
Sequence navigator - 3j7p: Chain SY
Sequence navigator - 3j7p: Chain SZ
Sequence navigator - 3j7p: Chain Sa
Sequence navigator - 3j7p: Chain Sb
Sequence navigator - 3j7p: Chain Sc
Sequence navigator - 3j7p: Chain Sd
Sequence navigator - 3j7p: Chain Se
Sequence navigator - 3j7p: Chain Sf
Sequence navigator - 3j7p: Chain Sg

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