Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3J7P

Structure of the 80S mammalian ribosome bound to eEF2

This is a non-PDB format compatible entry.

Replaces: 3J74Replaces: 1VX3Replaces: 1VX4Replaces: 1VX5

Functional Information from GO Data

Chain	GOid	namespace	contents
4	0003924	molecular_function	GTPase activity
4	0005525	molecular_function	GTP binding
A	0002181	biological_process	cytoplasmic translation
A	0003723	molecular_function	RNA binding
A	0003735	molecular_function	structural constituent of ribosome
A	0005840	cellular_component	ribosome
A	0006412	biological_process	translation
A	0015934	cellular_component	large ribosomal subunit
A	0022625	cellular_component	cytosolic large ribosomal subunit
A	0022626	cellular_component	cytosolic ribosome
A	0031090	cellular_component	organelle membrane
A	1990904	cellular_component	ribonucleoprotein complex
B	0003735	molecular_function	structural constituent of ribosome
B	0005840	cellular_component	ribosome
B	0006412	biological_process	translation
C	0003735	molecular_function	structural constituent of ribosome
C	0005840	cellular_component	ribosome
C	0006412	biological_process	translation
D	0003735	molecular_function	structural constituent of ribosome
D	0005840	cellular_component	ribosome
D	0006412	biological_process	translation
D	0008097	molecular_function	5S rRNA binding
E	0003735	molecular_function	structural constituent of ribosome
E	0005840	cellular_component	ribosome
E	0006412	biological_process	translation
F	0000463	biological_process	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
F	0003735	molecular_function	structural constituent of ribosome
F	0022625	cellular_component	cytosolic large ribosomal subunit
G	0042254	biological_process	ribosome biogenesis
G	1990904	cellular_component	ribonucleoprotein complex
H	0002181	biological_process	cytoplasmic translation
H	0003735	molecular_function	structural constituent of ribosome
H	0005840	cellular_component	ribosome
H	0006412	biological_process	translation
H	0019843	molecular_function	rRNA binding
H	0022625	cellular_component	cytosolic large ribosomal subunit
H	1990904	cellular_component	ribonucleoprotein complex
I	0003735	molecular_function	structural constituent of ribosome
I	0005840	cellular_component	ribosome
I	0006412	biological_process	translation
J	0003723	molecular_function	RNA binding
J	0003735	molecular_function	structural constituent of ribosome
J	0005515	molecular_function	protein binding
J	0005634	cellular_component	nucleus
J	0005654	cellular_component	nucleoplasm
J	0005730	cellular_component	nucleolus
J	0005737	cellular_component	cytoplasm
J	0005840	cellular_component	ribosome
J	0006412	biological_process	translation
J	0015934	cellular_component	large ribosomal subunit
J	0019843	molecular_function	rRNA binding
J	0022625	cellular_component	cytosolic large ribosomal subunit
J	0032435	biological_process	negative regulation of proteasomal ubiquitin-dependent protein catabolic process
J	0034504	biological_process	protein localization to nucleus
J	0098556	cellular_component	cytoplasmic side of rough endoplasmic reticulum membrane
J	1901798	biological_process	positive regulation of signal transduction by p53 class mediator
J	1990904	cellular_component	ribonucleoprotein complex
K	0003735	molecular_function	structural constituent of ribosome
K	0005840	cellular_component	ribosome
K	0006412	biological_process	translation
L	0003735	molecular_function	structural constituent of ribosome
L	0005840	cellular_component	ribosome
L	0006412	biological_process	translation
M	0003723	molecular_function	RNA binding
M	0003735	molecular_function	structural constituent of ribosome
M	0005737	cellular_component	cytoplasm
M	0005840	cellular_component	ribosome
M	0006412	biological_process	translation
M	0015934	cellular_component	large ribosomal subunit
M	0022625	cellular_component	cytosolic large ribosomal subunit
M	0031090	cellular_component	organelle membrane
M	0042273	biological_process	ribosomal large subunit biogenesis
M	0098556	cellular_component	cytoplasmic side of rough endoplasmic reticulum membrane
M	1990904	cellular_component	ribonucleoprotein complex
N	0003735	molecular_function	structural constituent of ribosome
N	0005840	cellular_component	ribosome
N	0006412	biological_process	translation
O	0003735	molecular_function	structural constituent of ribosome
O	0005840	cellular_component	ribosome
O	0006412	biological_process	translation
O	0015934	cellular_component	large ribosomal subunit
P	0003735	molecular_function	structural constituent of ribosome
P	0005840	cellular_component	ribosome
P	0006412	biological_process	translation
P	0015934	cellular_component	large ribosomal subunit
Q	0002181	biological_process	cytoplasmic translation
Q	0003723	molecular_function	RNA binding
Q	0003735	molecular_function	structural constituent of ribosome
Q	0005737	cellular_component	cytoplasm
Q	0005783	cellular_component	endoplasmic reticulum
Q	0005791	cellular_component	rough endoplasmic reticulum
Q	0005829	cellular_component	cytosol
Q	0005840	cellular_component	ribosome
Q	0006412	biological_process	translation
Q	0022625	cellular_component	cytosolic large ribosomal subunit
Q	0043232	cellular_component	intracellular non-membrane-bounded organelle
Q	1990904	cellular_component	ribonucleoprotein complex
R	0003723	molecular_function	RNA binding
R	0003735	molecular_function	structural constituent of ribosome
R	0005840	cellular_component	ribosome
R	0006412	biological_process	translation
R	0022625	cellular_component	cytosolic large ribosomal subunit
S	0003735	molecular_function	structural constituent of ribosome
S	0005840	cellular_component	ribosome
S	0006412	biological_process	translation
S	0022625	cellular_component	cytosolic large ribosomal subunit
SA	0000028	biological_process	ribosomal small subunit assembly
SA	0001618	molecular_function	virus receptor activity
SA	0002181	biological_process	cytoplasmic translation
SA	0003735	molecular_function	structural constituent of ribosome
SA	0005055	molecular_function	laminin receptor activity
SA	0005634	cellular_component	nucleus
SA	0005737	cellular_component	cytoplasm
SA	0005840	cellular_component	ribosome
SA	0005886	cellular_component	plasma membrane
SA	0006412	biological_process	translation
SA	0007155	biological_process	cell adhesion
SA	0015935	cellular_component	small ribosomal subunit
SA	0016020	cellular_component	membrane
SA	0022627	cellular_component	cytosolic small ribosomal subunit
SA	0030686	cellular_component	90S preribosome
SA	0043236	molecular_function	laminin binding
SA	0046718	biological_process	symbiont entry into host cell
SA	0098556	cellular_component	cytoplasmic side of rough endoplasmic reticulum membrane
SA	1990904	cellular_component	ribonucleoprotein complex
SB	0003735	molecular_function	structural constituent of ribosome
SB	0005634	cellular_component	nucleus
SB	0005730	cellular_component	nucleolus
SB	0005737	cellular_component	cytoplasm
SB	0005829	cellular_component	cytosol
SB	0005840	cellular_component	ribosome
SB	0006412	biological_process	translation
SB	0022627	cellular_component	cytosolic small ribosomal subunit
SB	0030154	biological_process	cell differentiation
SB	1990904	cellular_component	ribonucleoprotein complex
SC	0003723	molecular_function	RNA binding
SC	0003735	molecular_function	structural constituent of ribosome
SC	0005840	cellular_component	ribosome
SC	0006412	biological_process	translation
SC	0015935	cellular_component	small ribosomal subunit
SD	0003677	molecular_function	DNA binding
SD	0003723	molecular_function	RNA binding
SD	0003735	molecular_function	structural constituent of ribosome
SD	0005634	cellular_component	nucleus
SD	0005730	cellular_component	nucleolus
SD	0005737	cellular_component	cytoplasm
SD	0005739	cellular_component	mitochondrion
SD	0005743	cellular_component	mitochondrial inner membrane
SD	0005819	cellular_component	spindle
SD	0005840	cellular_component	ribosome
SD	0005856	cellular_component	cytoskeleton
SD	0006281	biological_process	DNA repair
SD	0006412	biological_process	translation
SD	0006417	biological_process	regulation of translation
SD	0006915	biological_process	apoptotic process
SD	0006974	biological_process	DNA damage response
SD	0007049	biological_process	cell cycle
SD	0015935	cellular_component	small ribosomal subunit
SD	0016020	cellular_component	membrane
SD	0016829	molecular_function	lyase activity
SD	0022626	cellular_component	cytosolic ribosome
SD	0022627	cellular_component	cytosolic small ribosomal subunit
SD	0051301	biological_process	cell division
SD	0098556	cellular_component	cytoplasmic side of rough endoplasmic reticulum membrane
SD	0140078	molecular_function	class I DNA-(apurinic or apyrimidinic site) endonuclease activity
SD	1990904	cellular_component	ribonucleoprotein complex
SD	2001235	biological_process	positive regulation of apoptotic signaling pathway
SE	0003723	molecular_function	RNA binding
SE	0003735	molecular_function	structural constituent of ribosome
SE	0005840	cellular_component	ribosome
SE	0006412	biological_process	translation
SF	0000028	biological_process	ribosomal small subunit assembly
SF	0003723	molecular_function	RNA binding
SF	0003729	molecular_function	mRNA binding
SF	0003735	molecular_function	structural constituent of ribosome
SF	0005840	cellular_component	ribosome
SF	0006412	biological_process	translation
SF	0015935	cellular_component	small ribosomal subunit
SF	0019843	molecular_function	rRNA binding
SF	0022627	cellular_component	cytosolic small ribosomal subunit
SF	1990904	cellular_component	ribonucleoprotein complex
SG	0003735	molecular_function	structural constituent of ribosome
SG	0005840	cellular_component	ribosome
SG	0006412	biological_process	translation
SH	0003735	molecular_function	structural constituent of ribosome
SH	0005840	cellular_component	ribosome
SH	0006412	biological_process	translation
SI	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SI	0003735	molecular_function	structural constituent of ribosome
SI	0005783	cellular_component	endoplasmic reticulum
SI	0005829	cellular_component	cytosol
SI	0005840	cellular_component	ribosome
SI	0006412	biological_process	translation
SI	0022626	cellular_component	cytosolic ribosome
SI	0022627	cellular_component	cytosolic small ribosomal subunit
SI	0032040	cellular_component	small-subunit processome
SI	0042274	biological_process	ribosomal small subunit biogenesis
SI	1990904	cellular_component	ribonucleoprotein complex
SJ	0003723	molecular_function	RNA binding
SJ	0003735	molecular_function	structural constituent of ribosome
SJ	0006412	biological_process	translation
SJ	0015935	cellular_component	small ribosomal subunit
SJ	0019843	molecular_function	rRNA binding
SL	0003735	molecular_function	structural constituent of ribosome
SL	0005840	cellular_component	ribosome
SL	0006412	biological_process	translation
SL	0022626	cellular_component	cytosolic ribosome
SL	0022627	cellular_component	cytosolic small ribosomal subunit
SL	0031090	cellular_component	organelle membrane
SL	0032040	cellular_component	small-subunit processome
SL	0042274	biological_process	ribosomal small subunit biogenesis
SL	0045202	cellular_component	synapse
SL	1990904	cellular_component	ribonucleoprotein complex
SM	0003735	molecular_function	structural constituent of ribosome
SM	0005840	cellular_component	ribosome
SM	0006412	biological_process	translation
SN	0003735	molecular_function	structural constituent of ribosome
SN	0005840	cellular_component	ribosome
SN	0006412	biological_process	translation
SO	0003735	molecular_function	structural constituent of ribosome
SO	0005840	cellular_component	ribosome
SO	0006412	biological_process	translation
SP	0000028	biological_process	ribosomal small subunit assembly
SP	0003723	molecular_function	RNA binding
SP	0003735	molecular_function	structural constituent of ribosome
SP	0005737	cellular_component	cytoplasm
SP	0005840	cellular_component	ribosome
SP	0006412	biological_process	translation
SP	0015935	cellular_component	small ribosomal subunit
SP	0022627	cellular_component	cytosolic small ribosomal subunit
SP	0098556	cellular_component	cytoplasmic side of rough endoplasmic reticulum membrane
SP	1990904	cellular_component	ribonucleoprotein complex
SQ	0000462	biological_process	maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SQ	0003723	molecular_function	RNA binding
SQ	0003735	molecular_function	structural constituent of ribosome
SQ	0005634	cellular_component	nucleus
SQ	0005730	cellular_component	nucleolus
SQ	0005737	cellular_component	cytoplasm
SQ	0005840	cellular_component	ribosome
SQ	0006412	biological_process	translation
SQ	0015935	cellular_component	small ribosomal subunit
SQ	0022627	cellular_component	cytosolic small ribosomal subunit
SQ	0032040	cellular_component	small-subunit processome
SQ	0042274	biological_process	ribosomal small subunit biogenesis
SQ	0098556	cellular_component	cytoplasmic side of rough endoplasmic reticulum membrane
SQ	1990904	cellular_component	ribonucleoprotein complex
SR	0003735	molecular_function	structural constituent of ribosome
SR	0005634	cellular_component	nucleus
SR	0005730	cellular_component	nucleolus
SR	0005737	cellular_component	cytoplasm
SR	0005829	cellular_component	cytosol
SR	0005840	cellular_component	ribosome
SR	0006412	biological_process	translation
SR	0022627	cellular_component	cytosolic small ribosomal subunit
SR	0032040	cellular_component	small-subunit processome
SR	0042274	biological_process	ribosomal small subunit biogenesis
SR	0098556	cellular_component	cytoplasmic side of rough endoplasmic reticulum membrane
SR	1990904	cellular_component	ribonucleoprotein complex
SS	0003676	molecular_function	nucleic acid binding
SS	0003723	molecular_function	RNA binding
SS	0003735	molecular_function	structural constituent of ribosome
SS	0005737	cellular_component	cytoplasm
SS	0005829	cellular_component	cytosol
SS	0005840	cellular_component	ribosome
SS	0006412	biological_process	translation
SS	0015935	cellular_component	small ribosomal subunit
SS	0019843	molecular_function	rRNA binding
SS	0022627	cellular_component	cytosolic small ribosomal subunit
SS	0098556	cellular_component	cytoplasmic side of rough endoplasmic reticulum membrane
SS	1990904	cellular_component	ribonucleoprotein complex
ST	0003735	molecular_function	structural constituent of ribosome
ST	0005840	cellular_component	ribosome
ST	0006412	biological_process	translation
SU	0003723	molecular_function	RNA binding
SU	0003735	molecular_function	structural constituent of ribosome
SU	0005737	cellular_component	cytoplasm
SU	0005840	cellular_component	ribosome
SU	0006412	biological_process	translation
SU	0015935	cellular_component	small ribosomal subunit
SU	0022627	cellular_component	cytosolic small ribosomal subunit
SU	0098556	cellular_component	cytoplasmic side of rough endoplasmic reticulum membrane
SU	1990904	cellular_component	ribonucleoprotein complex
SV	0000447	biological_process	endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SV	0000461	biological_process	endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
SV	0002181	biological_process	cytoplasmic translation
SV	0003735	molecular_function	structural constituent of ribosome
SV	0005737	cellular_component	cytoplasm
SV	0005783	cellular_component	endoplasmic reticulum
SV	0005791	cellular_component	rough endoplasmic reticulum
SV	0005829	cellular_component	cytosol
SV	0005840	cellular_component	ribosome
SV	0006412	biological_process	translation
SV	0022627	cellular_component	cytosolic small ribosomal subunit
SV	0043022	molecular_function	ribosome binding
SV	0098556	cellular_component	cytoplasmic side of rough endoplasmic reticulum membrane
SV	1990904	cellular_component	ribonucleoprotein complex
SW	0003735	molecular_function	structural constituent of ribosome
SW	0005840	cellular_component	ribosome
SW	0006412	biological_process	translation
SX	0002181	biological_process	cytoplasmic translation
SX	0003735	molecular_function	structural constituent of ribosome
SX	0005634	cellular_component	nucleus
SX	0005730	cellular_component	nucleolus
SX	0005737	cellular_component	cytoplasm
SX	0005783	cellular_component	endoplasmic reticulum
SX	0005791	cellular_component	rough endoplasmic reticulum
SX	0005829	cellular_component	cytosol
SX	0005840	cellular_component	ribosome
SX	0006412	biological_process	translation
SX	0015935	cellular_component	small ribosomal subunit
SX	0022627	cellular_component	cytosolic small ribosomal subunit
SX	0031090	cellular_component	organelle membrane
SX	0032040	cellular_component	small-subunit processome
SX	0042274	biological_process	ribosomal small subunit biogenesis
SX	0098556	cellular_component	cytoplasmic side of rough endoplasmic reticulum membrane
SX	1990145	biological_process	maintenance of translational fidelity
SX	1990904	cellular_component	ribonucleoprotein complex
SY	0003735	molecular_function	structural constituent of ribosome
SY	0005840	cellular_component	ribosome
SY	0006412	biological_process	translation
Sa	0002181	biological_process	cytoplasmic translation
Sa	0003729	molecular_function	mRNA binding
Sa	0003735	molecular_function	structural constituent of ribosome
Sa	0005737	cellular_component	cytoplasm
Sa	0005783	cellular_component	endoplasmic reticulum
Sa	0005791	cellular_component	rough endoplasmic reticulum
Sa	0005829	cellular_component	cytosol
Sa	0005840	cellular_component	ribosome
Sa	0006412	biological_process	translation
Sa	0022627	cellular_component	cytosolic small ribosomal subunit
Sa	0098556	cellular_component	cytoplasmic side of rough endoplasmic reticulum membrane
Sa	1990904	cellular_component	ribonucleoprotein complex
Sb	0003735	molecular_function	structural constituent of ribosome
Sb	0005840	cellular_component	ribosome
Sb	0006412	biological_process	translation
Sc	0000028	biological_process	ribosomal small subunit assembly
Sc	0002181	biological_process	cytoplasmic translation
Sc	0003735	molecular_function	structural constituent of ribosome
Sc	0005634	cellular_component	nucleus
Sc	0005730	cellular_component	nucleolus
Sc	0005737	cellular_component	cytoplasm
Sc	0005783	cellular_component	endoplasmic reticulum
Sc	0005791	cellular_component	rough endoplasmic reticulum
Sc	0005829	cellular_component	cytosol
Sc	0005840	cellular_component	ribosome
Sc	0006412	biological_process	translation
Sc	0022627	cellular_component	cytosolic small ribosomal subunit
Sc	0030490	biological_process	maturation of SSU-rRNA
Sc	0031090	cellular_component	organelle membrane
Sc	0032040	cellular_component	small-subunit processome
Sc	0042254	biological_process	ribosome biogenesis
Sc	0042274	biological_process	ribosomal small subunit biogenesis
Sc	0098556	cellular_component	cytoplasmic side of rough endoplasmic reticulum membrane
Sc	1990904	cellular_component	ribonucleoprotein complex
Sd	0002181	biological_process	cytoplasmic translation
Sd	0003735	molecular_function	structural constituent of ribosome
Sd	0005737	cellular_component	cytoplasm
Sd	0005783	cellular_component	endoplasmic reticulum
Sd	0005791	cellular_component	rough endoplasmic reticulum
Sd	0005829	cellular_component	cytosol
Sd	0005840	cellular_component	ribosome
Sd	0006412	biological_process	translation
Sd	0008270	molecular_function	zinc ion binding
Sd	0022627	cellular_component	cytosolic small ribosomal subunit
Sd	0046872	molecular_function	metal ion binding
Sd	0098556	cellular_component	cytoplasmic side of rough endoplasmic reticulum membrane
Sd	1990904	cellular_component	ribonucleoprotein complex
Se	0003735	molecular_function	structural constituent of ribosome
Se	0005840	cellular_component	ribosome
Se	0006412	biological_process	translation
Sf	0003735	molecular_function	structural constituent of ribosome
Sf	0005840	cellular_component	ribosome
Sf	0006412	biological_process	translation
Sg	0001891	cellular_component	phagocytic cup
Sg	0001934	biological_process	positive regulation of protein phosphorylation
Sg	0005080	molecular_function	protein kinase C binding
Sg	0005634	cellular_component	nucleus
Sg	0005654	cellular_component	nucleoplasm
Sg	0005737	cellular_component	cytoplasm
Sg	0005739	cellular_component	mitochondrion
Sg	0005829	cellular_component	cytosol
Sg	0005840	cellular_component	ribosome
Sg	0005886	cellular_component	plasma membrane
Sg	0006417	biological_process	regulation of translation
Sg	0006915	biological_process	apoptotic process
Sg	0007049	biological_process	cell cycle
Sg	0007369	biological_process	gastrulation
Sg	0008047	molecular_function	enzyme activator activity
Sg	0008656	molecular_function	cysteine-type endopeptidase activator activity involved in apoptotic process
Sg	0010629	biological_process	negative regulation of gene expression
Sg	0016020	cellular_component	membrane
Sg	0016567	biological_process	protein ubiquitination
Sg	0019899	molecular_function	enzyme binding
Sg	0019903	molecular_function	protein phosphatase binding
Sg	0030178	biological_process	negative regulation of Wnt signaling pathway
Sg	0030292	molecular_function	protein tyrosine kinase inhibitor activity
Sg	0030308	biological_process	negative regulation of cell growth
Sg	0030332	molecular_function	cyclin binding
Sg	0030335	biological_process	positive regulation of cell migration
Sg	0030425	cellular_component	dendrite
Sg	0030496	cellular_component	midbody
Sg	0030971	molecular_function	receptor tyrosine kinase binding
Sg	0031334	biological_process	positive regulation of protein-containing complex assembly
Sg	0032436	biological_process	positive regulation of proteasomal ubiquitin-dependent protein catabolic process
Sg	0032880	biological_process	regulation of protein localization
Sg	0033137	biological_process	negative regulation of peptidyl-serine phosphorylation
Sg	0035591	molecular_function	signaling adaptor activity
Sg	0042169	molecular_function	SH2 domain binding
Sg	0042803	molecular_function	protein homodimerization activity
Sg	0042995	cellular_component	cell projection
Sg	0042998	biological_process	positive regulation of Golgi to plasma membrane protein transport
Sg	0043022	molecular_function	ribosome binding
Sg	0043025	cellular_component	neuronal cell body
Sg	0043065	biological_process	positive regulation of apoptotic process
Sg	0043204	cellular_component	perikaryon
Sg	0043547	biological_process	positive regulation of GTPase activity
Sg	0045182	molecular_function	translation regulator activity
Sg	0045879	biological_process	negative regulation of smoothened signaling pathway
Sg	0048471	cellular_component	perinuclear region of cytoplasm
Sg	0048511	biological_process	rhythmic process
Sg	0050765	biological_process	negative regulation of phagocytosis
Sg	0051302	biological_process	regulation of cell division
Sg	0051434	molecular_function	BH3 domain binding
Sg	0051726	biological_process	regulation of cell cycle
Sg	0051898	biological_process	negative regulation of phosphatidylinositol 3-kinase/protein kinase B signal transduction
Sg	0051901	biological_process	positive regulation of mitochondrial depolarization
Sg	0071333	biological_process	cellular response to glucose stimulus
Sg	0071363	biological_process	cellular response to growth factor stimulus
Sg	0072344	biological_process	rescue of stalled ribosome
Sg	0106070	biological_process	regulation of adenylate cyclase-activating G protein-coupled receptor signaling pathway
Sg	1903751	biological_process	negative regulation of intrinsic apoptotic signaling pathway in response to hydrogen peroxide
Sg	1990630	cellular_component	IRE1-RACK1-PP2A complex
Sg	1990904	cellular_component	ribonucleoprotein complex
Sg	2000114	biological_process	regulation of establishment of cell polarity
Sg	2000543	biological_process	positive regulation of gastrulation
Sg	2001244	biological_process	positive regulation of intrinsic apoptotic signaling pathway
T	0003735	molecular_function	structural constituent of ribosome
T	0005737	cellular_component	cytoplasm
T	0005783	cellular_component	endoplasmic reticulum
T	0005829	cellular_component	cytosol
T	0005840	cellular_component	ribosome
T	0006412	biological_process	translation
T	0022625	cellular_component	cytosolic large ribosomal subunit
T	0031090	cellular_component	organelle membrane
T	1990904	cellular_component	ribonucleoprotein complex
U	0002181	biological_process	cytoplasmic translation
U	0003723	molecular_function	RNA binding
U	0003735	molecular_function	structural constituent of ribosome
U	0005634	cellular_component	nucleus
U	0005737	cellular_component	cytoplasm
U	0005840	cellular_component	ribosome
U	0006412	biological_process	translation
U	0008201	molecular_function	heparin binding
U	0015934	cellular_component	large ribosomal subunit
U	0022625	cellular_component	cytosolic large ribosomal subunit
U	0022626	cellular_component	cytosolic ribosome
U	0042802	molecular_function	identical protein binding
U	0045202	cellular_component	synapse
U	0046632	biological_process	alpha-beta T cell differentiation
U	0098556	cellular_component	cytoplasmic side of rough endoplasmic reticulum membrane
U	0098793	cellular_component	presynapse
U	0098978	cellular_component	glutamatergic synapse
U	0140236	biological_process	translation at presynapse
U	1990904	cellular_component	ribonucleoprotein complex
V	0000122	biological_process	negative regulation of transcription by RNA polymerase II
V	0001223	molecular_function	transcription coactivator binding
V	0003735	molecular_function	structural constituent of ribosome
V	0005654	cellular_component	nucleoplasm
V	0005730	cellular_component	nucleolus
V	0005737	cellular_component	cytoplasm
V	0005840	cellular_component	ribosome
V	0006412	biological_process	translation
V	0008284	biological_process	positive regulation of cell population proliferation
V	0010628	biological_process	positive regulation of gene expression
V	0015934	cellular_component	large ribosomal subunit
V	0022625	cellular_component	cytosolic large ribosomal subunit
V	0022626	cellular_component	cytosolic ribosome
V	0031625	molecular_function	ubiquitin protein ligase binding
V	0032986	biological_process	protein-DNA complex disassembly
V	0032991	cellular_component	protein-containing complex
V	0045202	cellular_component	synapse
V	0050821	biological_process	protein stabilization
V	0070180	molecular_function	large ribosomal subunit rRNA binding
V	0070314	biological_process	G1 to G0 transition
V	0072717	biological_process	cellular response to actinomycin D
V	0098556	cellular_component	cytoplasmic side of rough endoplasmic reticulum membrane
V	1901798	biological_process	positive regulation of signal transduction by p53 class mediator
V	1903450	biological_process	regulation of G1 to G0 transition
V	1990904	cellular_component	ribonucleoprotein complex
V	1990948	molecular_function	ubiquitin ligase inhibitor activity
V	2000059	biological_process	negative regulation of ubiquitin-dependent protein catabolic process
X	0003735	molecular_function	structural constituent of ribosome
X	0005840	cellular_component	ribosome
X	0006412	biological_process	translation
X	0019843	molecular_function	rRNA binding
Y	0002181	biological_process	cytoplasmic translation
Y	0003723	molecular_function	RNA binding
Y	0003735	molecular_function	structural constituent of ribosome
Y	0005654	cellular_component	nucleoplasm
Y	0005730	cellular_component	nucleolus
Y	0005737	cellular_component	cytoplasm
Y	0005840	cellular_component	ribosome
Y	0006364	biological_process	rRNA processing
Y	0006412	biological_process	translation
Y	0006977	biological_process	DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest
Y	0015934	cellular_component	large ribosomal subunit
Y	0022625	cellular_component	cytosolic large ribosomal subunit
Y	0022626	cellular_component	cytosolic ribosome
Y	0031090	cellular_component	organelle membrane
Y	0034644	biological_process	cellular response to UV
Y	0042273	biological_process	ribosomal large subunit biogenesis
Y	0045202	cellular_component	synapse
Y	0045727	biological_process	positive regulation of translation
Y	0048027	molecular_function	mRNA 5'-UTR binding
Y	0071479	biological_process	cellular response to ionizing radiation
Y	0071480	biological_process	cellular response to gamma radiation
Y	1902164	biological_process	positive regulation of DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator
Y	1902167	biological_process	positive regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
Y	1904803	biological_process	regulation of translation involved in cellular response to UV
Y	1990904	cellular_component	ribonucleoprotein complex
Z	0003735	molecular_function	structural constituent of ribosome
Z	0005654	cellular_component	nucleoplasm
Z	0005730	cellular_component	nucleolus
Z	0005737	cellular_component	cytoplasm
Z	0005783	cellular_component	endoplasmic reticulum
Z	0005791	cellular_component	rough endoplasmic reticulum
Z	0005829	cellular_component	cytosol
Z	0005840	cellular_component	ribosome
Z	0006364	biological_process	rRNA processing
Z	0006412	biological_process	translation
Z	0015934	cellular_component	large ribosomal subunit
Z	0022625	cellular_component	cytosolic large ribosomal subunit
Z	0022626	cellular_component	cytosolic ribosome
Z	0031090	cellular_component	organelle membrane
Z	0045202	cellular_component	synapse
Z	0098556	cellular_component	cytoplasmic side of rough endoplasmic reticulum membrane
Z	1990904	cellular_component	ribonucleoprotein complex
a	0003735	molecular_function	structural constituent of ribosome
a	0005840	cellular_component	ribosome
a	0006412	biological_process	translation
a	0015934	cellular_component	large ribosomal subunit
b	0002181	biological_process	cytoplasmic translation
b	0003735	molecular_function	structural constituent of ribosome
b	0005737	cellular_component	cytoplasm
b	0005840	cellular_component	ribosome
b	0006412	biological_process	translation
b	0015934	cellular_component	large ribosomal subunit
b	0022625	cellular_component	cytosolic large ribosomal subunit
b	0098556	cellular_component	cytoplasmic side of rough endoplasmic reticulum membrane
b	1990904	cellular_component	ribonucleoprotein complex
c	0003723	molecular_function	RNA binding
c	0003735	molecular_function	structural constituent of ribosome
c	0022625	cellular_component	cytosolic large ribosomal subunit
d	0002181	biological_process	cytoplasmic translation
d	0003735	molecular_function	structural constituent of ribosome
d	0005737	cellular_component	cytoplasm
d	0005840	cellular_component	ribosome
d	0006412	biological_process	translation
d	0015934	cellular_component	large ribosomal subunit
d	0022625	cellular_component	cytosolic large ribosomal subunit
d	0098556	cellular_component	cytoplasmic side of rough endoplasmic reticulum membrane
d	1990904	cellular_component	ribonucleoprotein complex
e	0002181	biological_process	cytoplasmic translation
e	0003735	molecular_function	structural constituent of ribosome
e	0005737	cellular_component	cytoplasm
e	0005840	cellular_component	ribosome
e	0006412	biological_process	translation
e	0015934	cellular_component	large ribosomal subunit
e	0022625	cellular_component	cytosolic large ribosomal subunit
e	0022626	cellular_component	cytosolic ribosome
e	0045202	cellular_component	synapse
e	0098556	cellular_component	cytoplasmic side of rough endoplasmic reticulum membrane
e	1990904	cellular_component	ribonucleoprotein complex
f	0003735	molecular_function	structural constituent of ribosome
f	0005840	cellular_component	ribosome
f	0006412	biological_process	translation
g	0003735	molecular_function	structural constituent of ribosome
g	0005730	cellular_component	nucleolus
g	0005737	cellular_component	cytoplasm
g	0005783	cellular_component	endoplasmic reticulum
g	0005829	cellular_component	cytosol
g	0005840	cellular_component	ribosome
g	0006412	biological_process	translation
g	0022625	cellular_component	cytosolic large ribosomal subunit
g	0022626	cellular_component	cytosolic ribosome
g	0045202	cellular_component	synapse
g	1990904	cellular_component	ribonucleoprotein complex
h	0000463	biological_process	maturation of LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
h	0003729	molecular_function	mRNA binding
h	0003735	molecular_function	structural constituent of ribosome
h	0005737	cellular_component	cytoplasm
h	0005840	cellular_component	ribosome
h	0006412	biological_process	translation
h	0015934	cellular_component	large ribosomal subunit
h	0022625	cellular_component	cytosolic large ribosomal subunit
h	0098556	cellular_component	cytoplasmic side of rough endoplasmic reticulum membrane
h	1990904	cellular_component	ribonucleoprotein complex
i	0003735	molecular_function	structural constituent of ribosome
i	0005840	cellular_component	ribosome
i	0006412	biological_process	translation
j	0003735	molecular_function	structural constituent of ribosome
j	0005840	cellular_component	ribosome
j	0006412	biological_process	translation
k	0003735	molecular_function	structural constituent of ribosome
k	0005840	cellular_component	ribosome
k	0006412	biological_process	translation
k	0022618	biological_process	protein-RNA complex assembly
k	0022625	cellular_component	cytosolic large ribosomal subunit
k	1990904	cellular_component	ribonucleoprotein complex
l	0002181	biological_process	cytoplasmic translation
l	0002227	biological_process	innate immune response in mucosa
l	0003735	molecular_function	structural constituent of ribosome
l	0005615	cellular_component	extracellular space
l	0005840	cellular_component	ribosome
l	0006412	biological_process	translation
l	0019731	biological_process	antibacterial humoral response
l	0022625	cellular_component	cytosolic large ribosomal subunit
l	0022626	cellular_component	cytosolic ribosome
l	0050830	biological_process	defense response to Gram-positive bacterium
l	0061844	biological_process	antimicrobial humoral immune response mediated by antimicrobial peptide
l	1990904	cellular_component	ribonucleoprotein complex
m	0003723	molecular_function	RNA binding
m	0003735	molecular_function	structural constituent of ribosome
m	0005634	cellular_component	nucleus
m	0005737	cellular_component	cytoplasm
m	0005840	cellular_component	ribosome
m	0006412	biological_process	translation
m	0015934	cellular_component	large ribosomal subunit
m	0016567	biological_process	protein ubiquitination
m	0019941	biological_process	modification-dependent protein catabolic process
m	0022627	cellular_component	cytosolic small ribosomal subunit
m	0031386	molecular_function	protein tag activity
m	0031625	molecular_function	ubiquitin protein ligase binding
m	0043229	cellular_component	intracellular organelle
m	0098556	cellular_component	cytoplasmic side of rough endoplasmic reticulum membrane
m	1990904	cellular_component	ribonucleoprotein complex
n	0003735	molecular_function	structural constituent of ribosome
n	0005840	cellular_component	ribosome
n	0006412	biological_process	translation
o	0003674	molecular_function	molecular_function
o	0003735	molecular_function	structural constituent of ribosome
o	0005737	cellular_component	cytoplasm
o	0005840	cellular_component	ribosome
o	0006412	biological_process	translation
o	0008150	biological_process	biological_process
o	0015934	cellular_component	large ribosomal subunit
o	0022625	cellular_component	cytosolic large ribosomal subunit
o	0098556	cellular_component	cytoplasmic side of rough endoplasmic reticulum membrane
o	1990904	cellular_component	ribonucleoprotein complex
p	0003735	molecular_function	structural constituent of ribosome
p	0005840	cellular_component	ribosome
p	0006412	biological_process	translation
r	0003735	molecular_function	structural constituent of ribosome
r	0005840	cellular_component	ribosome
r	0006412	biological_process	translation

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG 5 5101

Chain	Residue
5	G2584
g	GLY55
g	THR70
g	HIS73

site_id	AC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5102

Chain	Residue
5	A39
5	U3915

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG 5 5103

Chain	Residue
5	C41
5	U37
5	A38
5	G40

site_id	AC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 5 5104

Chain	Residue
5	U43
5	A44
5	U45

site_id	AC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5105

Chain	Residue
5	A47
5	G48

site_id	AC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5106

Chain	Residue
5	A51

site_id	AC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5107

Chain	Residue
5	G21
5	A56

site_id	AC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5108

Chain	Residue
5	A61
5	G63

site_id	AC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5109

Chain	Residue
5	A62
5	U333

site_id	BC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG 5 5110

Chain	Residue
5	A84
5	G85
5	G1383
5	C1384

site_id	BC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5112

Chain	Residue
5	A105

site_id	BC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5113

Chain	Residue
5	C112
5	G156

site_id	BC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5114

Chain	Residue
5	G114

site_id	BC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5115

Chain	Residue
5	A198
5	G240

site_id	BC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5116

Chain	Residue
5	A235

site_id	BC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5117

Chain	Residue
5	U231
5	A235

site_id	BC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5118

Chain	Residue
5	C282

site_id	BC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5119

Chain	Residue
5	G288
5	A4178

site_id	CC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5120

Chain	Residue
5	U291

site_id	CC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5121

Chain	Residue
5	A47
5	U291

site_id	CC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5122

Chain	Residue
5	U316
5	U4354

site_id	CC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5124

Chain	Residue
5	C351
5	G2343

site_id	CC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 5 5126

Chain	Residue
5	G356
5	C358
C	GLY98

site_id	CC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 5 5127

Chain	Residue
5	A355
5	G356
5	A359

site_id	CC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5128

Chain	Residue
5	A2332

site_id	CC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 5 5129

Chain	Residue
5	A407
5	G2330
5	G2331

site_id	CC9
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG 5 5130

Chain	Residue
5	A410
5	G415
5	U416
5	G2331

site_id	DC1
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 5 5131

Chain	Residue
5	G415
5	U416
5	G417

site_id	DC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG 5 5132

Chain	Residue
5	C422
5	G423
5	U424
8	A9
8	G10

site_id	DC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 5 5134

Chain	Residue
5	C1665
5	A2279
5	G2280

site_id	DC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5135

Chain	Residue
5	A2282

site_id	DC5
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5136

Chain	Residue
5	A2367
5	U2828

site_id	DC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 5 5137

Chain	Residue
5	A2368
5	A2370
5	U2826

site_id	DC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5138

Chain	Residue
5	C2393

site_id	DC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5139

Chain	Residue
5	A2401

site_id	DC9
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 5 5140

Chain	Residue
5	C2410
5	C2411
5	A2428

site_id	EC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5141

Chain	Residue
5	C2422
5	A2423

site_id	EC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5142

Chain	Residue
5	G2510

site_id	EC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5143

Chain	Residue
5	G2514
5	G2516

site_id	EC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5144

Chain	Residue
5	G2677

site_id	EC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 5 5145

Chain	Residue
5	G2402
5	A2783
5	C2784

site_id	EC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 5 5146

Chain	Residue
5	A2789
5	G2827
5	U2828

site_id	EC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5147

Chain	Residue
5	C2792

site_id	EC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG 5 5148

Chain	Residue
5	A1599
5	A1600
5	G2793
5	C2794

site_id	EC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5149

Chain	Residue
5	A2845

site_id	FC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5150

Chain	Residue
5	A2857

site_id	FC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5151

Chain	Residue
5	A2879
5	A3629

site_id	FC3
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5152

Chain	Residue
5	C3632

site_id	FC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5153

Chain	Residue
5	G3634
5	C3636

site_id	FC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 5 5154

Chain	Residue
5	A3642
5	U3644
5	U3645

site_id	FC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG 5 5155

Chain	Residue
5	C3701
5	U3704
5	G3705
5	U3745

site_id	FC7
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG 5 5156

Chain	Residue
5	G3689
5	A3747
5	A3748
5	U3818

site_id	FC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5158

Chain	Residue
5	U3778

site_id	FC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5159

Chain	Residue
5	A3783

site_id	GC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5160

Chain	Residue
5	A3817

site_id	GC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5161

Chain	Residue
5	A2363
5	U3853

site_id	GC3
Number of Residues	6
Details	BINDING SITE FOR RESIDUE MG 5 5162

Chain	Residue
5	A1324
5	C1325
5	G3875
5	A3876
5	A3877
5	G3879

site_id	GC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 5 5163

Chain	Residue
5	C1678
5	G3913
5	U3914

site_id	GC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 5 5164

Chain	Residue
5	U3912
5	C4193
5	U4194

site_id	GC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG 5 5165

Chain	Residue
5	G40
5	C41
5	U3915
5	G3916

site_id	GC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5166

Chain	Residue
5	A3917

site_id	GC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 5 5168

Chain	Residue
5	U3920
5	G4184
A	PRO206

site_id	GC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5169

Chain	Residue
5	A3923
5	C3924

site_id	HC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5170

Chain	Residue
5	U35
5	U4188

site_id	HC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5171

Chain	Residue
5	G1734
5	U1735

site_id	HC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5172

Chain	Residue
5	A4214
5	C4215

site_id	HC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5173

Chain	Residue
5	G4235
5	C4332

site_id	HC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5174

Chain	Residue
5	A4239

site_id	HC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5175

Chain	Residue
5	A4281
D	TYR31

site_id	HC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5177

Chain	Residue
5	A4385

site_id	HC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 5 5178

Chain	Residue
5	G1633
5	G1641
5	G4534

site_id	HC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG 5 5179

Chain	Residue
5	A1632
5	G1633
5	A4535
A	ALA203
A	ASN205

site_id	IC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5180

Chain	Residue
5	A4533

site_id	IC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 5 5181

Chain	Residue
5	U1656
5	G4392
5	G4448

site_id	IC3
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG 5 5182

Chain	Residue
5	G4393
5	A4394
5	C4443
5	C4444
5	U4445

site_id	IC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 5 5183

Chain	Residue
5	G1321
5	A4394
5	U4445

site_id	IC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5184

Chain	Residue
5	G4401

site_id	IC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5185

Chain	Residue
5	C4417

site_id	IC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5186

Chain	Residue
5	A1871

site_id	IC8
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 5 5187

Chain	Residue
5	A3901
5	A3902
5	G4451

site_id	IC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5188

Chain	Residue
5	A3902
5	G4451

site_id	JC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5189

Chain	Residue
5	A4479
5	A4480

site_id	JC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5190

Chain	Residue
5	G2851
5	U2852

site_id	JC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG 5 5191

Chain	Residue
5	A2850
5	G2851
5	U2852
5	A4496

site_id	JC4
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5192

Chain	Residue
5	C3833
5	U4497

site_id	JC5
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 5 5193

Chain	Residue
5	G4451
5	G4522
5	U4557

site_id	JC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 5 5194

Chain	Residue
5	C4519
5	G4520
5	U4521

site_id	JC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5196

Chain	Residue
5	A4464

site_id	JC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG 5 5197

Chain	Residue
5	G3899
5	U4521
5	G4522
5	A4523

site_id	JC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5198

Chain	Residue
5	G1592
5	U4526

site_id	KC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5199

Chain	Residue
5	G4528
5	G4529

site_id	KC2
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5200

Chain	Residue
5	G3815
5	G4538

site_id	KC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 5 5201

Chain	Residue
5	U1591
5	G1592
5	U4556

site_id	KC4
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5202

Chain	Residue
5	G1595

site_id	KC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5203

Chain	Residue
5	U4682

site_id	KC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5204

Chain	Residue
5	A4705

site_id	KC7
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5206

Chain	Residue
5	G4650
5	A4651

site_id	KC8
Number of Residues	4
Details	BINDING SITE FOR RESIDUE MG 5 5207

Chain	Residue
5	G4751
5	U4752
5	U4946
5	C4948

site_id	KC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5208

Chain	Residue
5	G1895

site_id	LC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5209

Chain	Residue
5	C1318
5	U1656

site_id	LC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5210

Chain	Residue
5	G1680

site_id	LC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5211

Chain	Residue
5	C1318
5	U1659

site_id	LC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 5 5212

Chain	Residue
5	C322
5	G4355
5	G4356

site_id	LC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 5 5213

Chain	Residue
5	U416

site_id	LC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 5 5214

Chain	Residue
5	U354
5	A378
5	MG5215

site_id	LC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE MG 5 5215

Chain	Residue
5	A353
5	U354
5	A378
5	G379
5	MG5214

site_id	LC8
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5216

Chain	Residue
5	U380
5	G415

site_id	LC9
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5217

Chain	Residue
5	G1335
5	C2346

site_id	MC1
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 5 5218

Chain	Residue
5	A4665
B	LYS373

site_id	MC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 7 201

Chain	Residue
7	A42

site_id	MC3
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 7 202

Chain	Residue
7	U53
7	A54
7	A55

site_id	MC4
Number of Residues	3
Details	BINDING SITE FOR RESIDUE MG 7 203

Chain	Residue
7	U53
7	A55
7	G56

site_id	MC5
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 7 204

Chain	Residue
7	G65

site_id	MC6
Number of Residues	2
Details	BINDING SITE FOR RESIDUE MG 7 205

Chain	Residue
5	G1895
7	A83

site_id	MC7
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 8 202

Chain	Residue
8	U14

site_id	MC8
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 8 203

Chain	Residue
8	A20

site_id	MC9
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 8 204

Chain	Residue
8	G151

site_id	NC1
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG P 201

Chain	Residue
P	TYR130

site_id	NC2
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG V 201

Chain	Residue
V	ASN50

site_id	NC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN j 101

Chain	Residue
j	CYS19
j	CYS22
j	CYS34
j	CYS37

site_id	NC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN m 201

Chain	Residue
m	CYS96
m	CYS99
m	CYS110
m	CYS115

site_id	NC5
Number of Residues	5
Details	BINDING SITE FOR RESIDUE ZN o 201

Chain	Residue
o	CYS12
o	CYS15
o	CYS72
o	CYS77
o	SER79

site_id	NC6
Number of Residues	1
Details	BINDING SITE FOR RESIDUE MG 4 901

Chain	Residue
4	ASP29

Functional Information from PROSITE/UniProt

site_id	PS00299
Number of Residues	26
Details	UBIQUITIN_1 Ubiquitin domain signature. KakIqDkegIPpdqQrLIFaGkqleD

Chain	Residue	Details
m	LYS27-ASP52
Sf	LYS27-ASP52
Se	LYS-49-ASP-24

site_id	PS01257
Number of Residues	22
Details	RIBOSOMAL_L10E Ribosomal protein L10e signature. ADRlqtGMRgAFGKPqGtvARV

Chain	Residue	Details
I	ALA108-VAL129

site_id	PS00474
Number of Residues	24
Details	RIBOSOMAL_L3 Ribosomal protein L3 signature. FgqdemiDviGvTkGKGykGvtsR

Chain	Residue	Details
B	PHE211-ARG234

site_id	PS01189
Number of Residues	19
Details	RIBOSOMAL_S12E Ribosomal protein S12e signature. ALQevLktAlihDGLarGI

Chain	Residue	Details
SM	ALA17-ILE35

site_id	PS00712
Number of Residues	16
Details	RIBOSOMAL_S17E Ribosomal protein S17e signature. IpSKkLRNkIAGYvTH

Chain	Residue	Details
SR	ILE41-HIS56

site_id	PS00628
Number of Residues	20
Details	RIBOSOMAL_S19E Ribosomal protein S19e signature. PshfsrgSksVaRrVLQaLE

Chain	Residue	Details
ST	PRO89-GLU108

site_id	PS00526
Number of Residues	20
Details	RIBOSOMAL_L19E Ribosomal protein L19e signature. QKRLaSsvlrCGkkkVWLDP

Chain	Residue	Details
R	GLN7-PRO26

site_id	PS00687
Number of Residues	8
Details	ALDEHYDE_DEHYDR_GLU Aldehyde dehydrogenases glutamic acid active site. GESSGKNV

Chain	Residue	Details
C	GLY15-VAL22

site_id	PS00939
Number of Residues	27
Details	RIBOSOMAL_L1E Ribosomal protein L1e signature. NttqKryAIcSALaASAlpalvmsKGH

Chain	Residue	Details
C	ASN116-HIS142

site_id	PS00709
Number of Residues	25
Details	RIBOSOMAL_L30E_1 Ribosomal protein L30e signature 1. SgkyvlGyKqtLKmiRqGkaKlVIL

Chain	Residue	Details
c	SER24-LEU48

site_id	PS00993
Number of Residues	21
Details	RIBOSOMAL_L30E_2 Ribosomal protein L30e signature 2. ELGTacGKyyrvctLaIiDpG

Chain	Residue	Details
c	GLU80-GLY100

site_id	PS01145
Number of Residues	14
Details	RIBOSOMAL_L34E Ribosomal protein L34e signature. TaSnKtrlsRTPGN

Chain	Residue	Details
g	THR15-ASN28

site_id	PS01106
Number of Residues	18
Details	RIBOSOMAL_L18E Ribosomal protein L18e signature. KrLfmSRtnRPpLSLsRM

Chain	Residue	Details
Q	LYS49-MET66

site_id	PS00632
Number of Residues	25
Details	RIBOSOMAL_S4 Ribosomal protein S4 signature. LErRLqtqVFKlglAkSihhARvLI

Chain	Residue	Details
SJ	LEU106-ILE130

site_id	PS01194
Number of Residues	24
Details	RIBOSOMAL_L15E Ribosomal protein L15e signature. DKARrLGYkAkqGYVIYRiRVrRG

Chain	Residue	Details
N	ASP46-GLY69

site_id	PS00323
Number of Residues	25
Details	RIBOSOMAL_S19 Ribosomal protein S19 signature. NGKtfnqveIkpemIGhyLGEFsiT

Chain	Residue	Details
SP	ASN98-THR122

site_id	PS00056
Number of Residues	13
Details	RIBOSOMAL_S17 Ribosomal protein S17 signature. GDiVtVgEcRPLS

Chain	Residue	Details
SL	GLY123-SER135

site_id	PS00585
Number of Residues	33
Details	RIBOSOMAL_S5 Ribosomal protein S5 signature. GQrtrFkAfvAIGDyn.GhVGlGvkcsk.EVat.AI

Chain	Residue	Details
SC	GLY119-ILE151

site_id	PS00634
Number of Residues	33
Details	RIBOSOMAL_L30 Ribosomal protein L30 signature. VLqlLrLrQifNgTfvklnkasinMLriVepYI

Chain	Residue	Details
F	VAL110-ILE142

site_id	PS00528
Number of Residues	15
Details	RIBOSOMAL_S4E Ribosomal protein S4e signature. HlKRVAaPkhWmLdK

Chain	Residue	Details
SE	HIS8-LYS22

site_id	PS01077
Number of Residues	20
Details	RIBOSOMAL_L37E Ribosomal protein L37e signature. GTsSfGkRrnkt.HtlCrRCG

Chain	Residue	Details
j	GLY4-GLY23

site_id	PS00361
Number of Residues	16
Details	RIBOSOMAL_S10 Ribosomal protein S10 signature. AkekNLkvkGPVrMPT

Chain	Residue	Details
SU	ALA43-THR58

site_id	PS01073
Number of Residues	18
Details	RIBOSOMAL_L24E Ribosomal protein L24e signature. FsGykIyPGhGrrYaRtD

Chain	Residue	Details
W	PHE8-ASP25

site_id	PS01190
Number of Residues	11
Details	RIBOSOMAL_L36E Ribosomal protein L36e signature. PYERRaMELLK

Chain	Residue	Details
i	PRO52-LYS62

site_id	PS00646
Number of Residues	14
Details	RIBOSOMAL_S13_1 Ribosomal protein S13 signature. RGlRHfwGlrVRGQ

Chain	Residue	Details
SS	ARG121-GLN134

site_id	PS00578
Number of Residues	12
Details	RIBOSOMAL_S6E Ribosomal protein S6e signature. ISGGnDkqGfPM

Chain	Residue	Details
SG	ILE52-MET63

site_id	PS01144
Number of Residues	15
Details	RIBOSOMAL_L31E Ribosomal protein L31e signature. VRIDtrLNkAvWaKG

Chain	Residue	Details
d	VAL62-GLY76

site_id	PS00049
Number of Residues	27
Details	RIBOSOMAL_L14 Ribosomal protein L14 signature. AVVIrqrksyrrk.DGvflyFedNagVI

Chain	Residue	Details
V	ALA79-ILE105

site_id	PS01108
Number of Residues	19
Details	RIBOSOMAL_L24 Ribosomal protein L24 signature. DDeVqVVrGhyKGqqiGkV

Chain	Residue	Details
Y	ASP52-VAL70

site_id	PS00055
Number of Residues	8
Details	RIBOSOMAL_S12 Ribosomal protein S12 signature. KqPNSAiR

Chain	Residue	Details
SX	LYS60-ARG67

site_id	PS00359
Number of Residues	16
Details	RIBOSOMAL_L11 Ribosomal protein L11 signature. KeIlGTaqSVGcNVdG

Chain	Residue	Details
K	LYS130-GLY145

site_id	PS00783
Number of Residues	24
Details	RIBOSOMAL_L13 Ribosomal protein L13 signature. VRGMLPhktkrGQaaldrLkVFdG

Chain	Residue	Details
O	VAL84-GLY107

site_id	PS00961
Number of Residues	9
Details	RIBOSOMAL_S28E Ribosomal protein S28e signature. ESEREARrL

Chain	Residue	Details
Sc	GLU60-LEU68

site_id	PS00053
Number of Residues	18
Details	RIBOSOMAL_S8 Ribosomal protein S8 signature. GfiVLTTSaGIMdheeAR

Chain	Residue	Details
SW	GLY100-ARG117

site_id	PS00475
Number of Residues	32
Details	RIBOSOMAL_L15 Ribosomal protein L15 signature. KVLGkGkLpkqp.ViVkakfFSrrAeekIkgvG

Chain	Residue	Details
a	LYS110-GLY141

site_id	PS00052
Number of Residues	27
Details	RIBOSOMAL_S7 Ribosomal protein S7 signature. ErLtnsMMmhgrnnGKKlmtvrIVkhA

Chain	Residue	Details
SF	GLU70-ALA96

site_id	PS00358
Number of Residues	17
Details	RIBOSOMAL_L5 Ribosomal protein L5 signature. LeqLTGQtpVfSkARyT

Chain	Residue	Details
J	LEU40-THR56

site_id	PS00700
Number of Residues	22
Details	RIBOSOMAL_L6_2 Ribosomal protein L6 signature 2. QattVknKdiRkFlDGIYVseK

Chain	Residue	Details
H	GLN163-LYS184

site_id	PS00467
Number of Residues	12
Details	RIBOSOMAL_L2 Ribosomal protein L2 signature. PrvRGVAmNPvE

Chain	Residue	Details
A	PRO197-GLU208

site_id	PS01105
Number of Residues	22
Details	RIBOSOMAL_L35AE Ribosomal protein L35Ae signature. GKVtRaHGnsGmVrAkFrsnLP

Chain	Residue	Details
f	GLY72-PRO93

site_id	PS00360
Number of Residues	19
Details	RIBOSOMAL_S9 Ribosomal protein S9 signature. GGGhvAQiyAirqSiSKAL

Chain	Residue	Details
SQ	GLY74-LEU92

site_id	PS00051
Number of Residues	17
Details	RIBOSOMAL_L39E Ribosomal protein L39e signature. KTgnkIryNskrRHWRR

Chain	Residue	Details
l	LYS30-ARG46

site_id	PS00580
Number of Residues	21
Details	RIBOSOMAL_L32E Ribosomal protein L32e signature. FiRhqsdRyvKIkrn..WRKprG

Chain	Residue	Details
e	PHE20-GLY40

site_id	PS00464
Number of Residues	25
Details	RIBOSOMAL_L22 Ribosomal protein L22 signature. RrrTyRAhGRinpymsspCHIEMiL

Chain	Residue	Details
P	ARG126-LEU150

site_id	PS01168
Number of Residues	33
Details	RIBOSOMAL_S27E Ribosomal protein S27e signature. KCpgCykittvFShAqtvvlCvgCStvLcqPtG

Chain	Residue	Details
Sb	LYS36-GLY68

site_id	PS00054
Number of Residues	23
Details	RIBOSOMAL_S11 Ribosomal protein S11 signature. LrALarS.GMkIgrieDvTPiPSD

Chain	Residue	Details
SO	LEU116-ASP138

site_id	PS01172
Number of Residues	12
Details	RIBOSOMAL_L44E Ribosomal protein L44e signature. KtTKKivLRleC

Chain	Residue	Details
o	LYS61-CYS72

site_id	PS00362
Number of Residues	31
Details	RIBOSOMAL_S15 Ribosomal protein S15 signature. VrkHLernRkDkdAkfrLilIesrihrLarY

Chain	Residue	Details
SN	VAL98-TYR128

site_id	PS01193
Number of Residues	20
Details	RIBOSOMAL_S8E Ribosomal protein S8e signature. RrkTGGkrkpy.HkKrKyELG

Chain	Residue	Details
SI	ARG11-GLY30

site_id	PS00548
Number of Residues	37
Details	RIBOSOMAL_S3 Ribosomal protein S3 signature. AKsmkfvdGlMihSgdpVnyyVDtavrhvlLrqGvlG

Chain	Residue	Details
SD	ALA147-GLY183

site_id	PS01082
Number of Residues	18
Details	RIBOSOMAL_L7AE Ribosomal protein L7Ae signature. CrkmgVPYciIkGKarLG

Chain	Residue	Details
G	CYS174-GLY191

site_id	PS00050
Number of Residues	16
Details	RIBOSOMAL_L23 Ribosomal protein L23 signature. KKAYVRLApdydaldV

Chain	Residue	Details
X	LYS134-VAL149

site_id	PS00301
Number of Residues	16
Details	G_TR_1 Translational (tr)-type guanine nucleotide-binding (G) domain signature. DTrkdEQeRCITIksT

Chain	Residue	Details
4	ASP58-THR73

site_id	PS01107
Number of Residues	12
Details	RIBOSOMAL_L27E Ribosomal protein L27e signature. GKNkWFFqkLRF

Chain	Residue	Details
Z	GLY125-PHE136

site_id	PS00733
Number of Residues	8
Details	RIBOSOMAL_S26E Ribosomal protein S26e signature. YCVSCAIH

Chain	Residue	Details
Sa	TYR73-HIS80

site_id	PS00948
Number of Residues	14
Details	RIBOSOMAL_S7E Ribosomal protein S7e signature. RLvRELEKKFSgKH

Chain	Residue	Details
SH	ARG78-HIS91

site_id	PS01104
Number of Residues	15
Details	RIBOSOMAL_L13E Ribosomal protein L13e signature. RaGRGFSLeELrvaG

Chain	Residue	Details
L	ARG71-GLY85

site_id	PS01170
Number of Residues	19
Details	RIBOSOMAL_L6E Ribosomal protein L6e signature. NrvPLRRthqkFVIATSt.K

Chain	Residue	Details
E	ASN178-LYS196

site_id	PS00962
Number of Residues	12
Details	RIBOSOMAL_S2_1 Ribosomal protein S2 signature 1. VlKFLAAGTHLG

Chain	Residue	Details
SA	VAL15-GLY26

site_id	PS00963
Number of Residues	25
Details	RIBOSOMAL_S2_2 Ribosomal protein S2 signature 2. PrlLVVtDpraDhqpLtEasyvNLP

Chain	Residue	Details
SA	PRO119-PRO143

site_id	PS00996
Number of Residues	9
Details	RIBOSOMAL_S21E Ribosomal protein S21e signature. LYVPRKCSA

Chain	Residue	Details
SV	LEU11-ALA19

site_id	PS00579
Number of Residues	15
Details	RIBOSOMAL_L29 Ribosomal protein L29 signature. KLSKIRvVRKSIARV

Chain	Residue	Details
h	LYS43-VAL57

site_id	PS01171
Number of Residues	26
Details	RIBOSOMAL_L21E Ribosomal protein L21e signature. GDiVdikgmgtvqk.GmpHkcYhGkTG

Chain	Residue	Details
T	GLY37-GLY62

site_id	PS00529
Number of Residues	23
Details	RIBOSOMAL_S24E Ribosomal protein S24e signature. FGggKTtGFGmIYDSldyakknE

Chain	Residue	Details
SY	PHE64-GLU86

site_id	PS00678
Number of Residues	15
Details	WD_REPEATS_1 Trp-Asp (WD) repeats signature. ALSGswDgTLRLWDL

Chain	Residue	Details
Sg	ALA78-LEU92
Sg	ILE120-THR134
Sg	ILE165-LEU179
Sg	CYS207-LEU221

site_id	PS00527
Number of Residues	23
Details	RIBOSOMAL_S14 Ribosomal protein S14 signature. RvCsnrhglirkyg.LNMCRqCFR

Chain	Residue	Details
Sd	ARG22-ARG44

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	MOD_RES: N-acetylmethionine => ECO:0000250\|UniProtKB:P63244

Chain	Residue	Details
Sg	MET1
Sd	CYS24
Sd	CYS39
Sd	CYS42

site_id	SWS_FT_FI2
Number of Residues	1
Details	MOD_RES: N-acetylthreonine; in Guanine nucleotide-binding protein subunit beta-2-like 1, N-terminally processed => ECO:0000250\|UniProtKB:P63244

Chain	Residue	Details
Sg	THR2
SS	LYS106

site_id	SWS_FT_FI3
Number of Residues	4
Details	MOD_RES: Phosphothreonine => ECO:0000250\|UniProtKB:P63244

Chain	Residue	Details
Sg	THR6
Sg	THR10
Sg	THR96
Sg	THR277

site_id	SWS_FT_FI4
Number of Residues	1
Details	MOD_RES: Phosphotyrosine; by ABL1 => ECO:0000250\|UniProtKB:P63244

Chain	Residue	Details
Sg	TYR52
SU	LYS75
SS	LYS106

site_id	SWS_FT_FI5
Number of Residues	1
Details	MOD_RES: N6-acetyllysine => ECO:0000250\|UniProtKB:P63244

Chain	Residue	Details
Sg	LYS130
J	LYS154

site_id	SWS_FT_FI6
Number of Residues	1
Details	MOD_RES: N6-acetyllysine => ECO:0000250\|UniProtKB:P68040

Chain	Residue	Details
m	LYS63
SD	ARG65
SD	ARG67
m	LYS33
m	LYS48
Sg	LYS183

site_id	SWS_FT_FI7
Number of Residues	1
Details	MOD_RES: Phosphotyrosine => ECO:0000250\|UniProtKB:P63244

Chain	Residue	Details
Sg	TYR228
SU	LYS8

site_id	SWS_FT_FI8
Number of Residues	3
Details	MOD_RES: Phosphoserine => ECO:0000250\|UniProtKB:P63244

Chain	Residue	Details
Sg	SER276
Sg	SER278
Sg	SER279

site_id	SWS_FT_FI9
Number of Residues	1
Details	MOD_RES: Phosphothreonine => ECO:0000250\|UniProtKB:P68040

Chain	Residue	Details
Sg	THR316

site_id	SWS_FT_FI10
Number of Residues	2
Details	MOD_RES: Phosphothreonine => ECO:0000250\|UniProtKB:P23396

Chain	Residue	Details
SD	THR220
SD	THR242

site_id	SWS_FT_FI11
Number of Residues	1
Details	MOD_RES: Phosphothreonine; by CDK1 and PKC/PRKCD => ECO:0000250\|UniProtKB:P23396

Chain	Residue	Details
SD	THR221

site_id	SWS_FT_FI12
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000250\|UniProtKB:P23396

Chain	Residue	Details
SD	LYS90
SD	LYS202

site_id	SWS_FT_FI13
Number of Residues	2
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0000250\|UniProtKB:P23396

Chain	Residue	Details
SD	LYS230

site_id	SWS_FT_FI14
Number of Residues	1
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate => ECO:0000250\|UniProtKB:P23396

Chain	Residue	Details
SD	LYS214

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		Validation report (PDF)