6HCF

Structure of the rabbit 80S ribosome stalled on globin mRNA at the stop codon

This is a large structure.

Summary for 6HCF

EMDB information0192
Descriptor18S ribosomal RNA, uS2, 40S ribosomal protein S3a, ... (91 entities in total)
Functional Keywordstranslation, quality control, ribosome
Biological sourceHomo sapiens
More
Total number of polymer chains87
Total molecular weight3572567.59
Authors
Juszkiewicz, S.,Chandrasekaran, V.,Lin, Z.,Kraatz, S.,Ramakrishnan, V.,Hegde, R.S. (deposition date: 2018-08-14, release date: 2018-10-17, Last modification date: 2019-01-23)
Primary citation
Juszkiewicz, S.,Chandrasekaran, V.,Lin, Z.,Kraatz, S.,Ramakrishnan, V.,Hegde, R.S.
ZNF598 Is a Quality Control Sensor of Collided Ribosomes.
Mol. Cell, 72:469-481.e7, 2018
PubMed: 30293783 (PDB entries with the same primary citation)
DOI: 10.1016/j.molcel.2018.08.037
MImport into Mendeley
Experimental method
ELECTRON MICROSCOPY
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Structure validation

ClashscoreRamachandran outliersSidechain outliersRNA backbone5 0.2% 1.4% 0.40MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures

More Asymmetric unit images

Molmil generated image of 6hcf
no rotation
Molmil generated image of 6hcf
rotated about x axis by 90°
Molmil generated image of 6hcf
rotated about y axis by 90°
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