Structure of a mammalian ribosomal termination complex with ABCE1, eRF1(AAQ), and the UAA stop codon

This is a large structure.

Summary for 3JAG

Related3JAH 3JAI
EMDB information3038 3039 3040
DescriptoruL2, uL3, uL4, ... (91 entities in total)
Functional Keywordstermination, erf1, abce1, ribosome
Biological sourceHomo sapiens (human)
Total number of polymer chains87
Total molecular weight3344157.49
Brown, A.,Shao, S.,Murray, J.,Hegde, R.S.,Ramakrishnan, V. (deposition date: 2015-06-10, release date: 2015-08-12, Last modification date: 2018-07-18)
Primary citation
Brown, A.,Shao, S.,Murray, J.,Hegde, R.S.,Ramakrishnan, V.
Structural basis for stop codon recognition in eukaryotes.
Nature, 524:493-496, 2015
PubMed: 26245381 (PDB entries with the same primary citation)
DOI: 10.1038/nature14896
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliersRNA backbone7 3.3% 12.0% 0.41MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures
Download full validation reportDownload
PDB entries from 2020-10-21