Structure of a mammalian ribosomal termination complex with ABCE1, eRF1(AAQ), and the UAG stop codon

This is a large structure.

Summary for 3JAH

Related3JAG 3JAI
EMDB information3039 3038 3040
DescriptoruL2, uL3, uL4, ... (91 entities in total)
Functional Keywordstermination, erf1, abce1, ribosome
Biological sourceHomo sapiens (human)
Total number of polymer chains87
Total molecular weight3344057.37
Brown, A.,Shao, S.,Murray, J.,Hegde, R.S.,Ramakrishnan, V. (deposition date: 2015-06-10, release date: 2015-08-12, Last modification date: 2018-07-18)
Primary citation
Brown, A.,Shao, S.,Murray, J.,Hegde, R.S.,Ramakrishnan, V.
Structural basis for stop codon recognition in eukaryotes.
Nature, 524:493-496, 2015
PubMed: 26245381 (PDB entries with the same primary citation)
DOI: 10.1038/nature14896
MImport into Mendeley
Experimental method

Structure validation

Ramachandran outliersSidechain outliersRNA backbone 3.5% 12.7% 0.39MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures
Download full validation reportDownload
PDB entries from 2020-10-14