Cryo-EM structure of the yeast spliceosome at 3.6 angstrom resolution

Summary for 3JB9

EMDB information6413
DescriptorPre-mRNA-splicing factor spp42, Pre-mRNA-splicing factor cwf10, U5 snRNA, ... (37 entities in total)
Functional Keywordsspliceosome, u2/u5/u6, lariat, rna binding protein-rna complex, rna binding protein/rna
Biological sourceSchizosaccharomyces pombe 972h- (Fission yeast)
Total number of polymer chains43
Total molecular weight1789825.08
Yan, C.,Hang, J.,Wan, R.,Huang, M.,Wong, C.,Shi, Y. (deposition date: 2015-08-09, release date: 2015-09-23, Last modification date: 2019-12-11)
Primary citation
Yan, C.,Hang, J.,Wan, R.,Huang, M.,Wong, C.,Shi, Y.
Structure of a yeast spliceosome at 3.6-angstrom resolution
Science, 349:1182-1191, 2015
PubMed: 26292707 (PDB entries with the same primary citation)
DOI: 10.1126/science.aac7629
MImport into Mendeley
Experimental method

Structure validation

Ramachandran outliersSidechain outliersRNA backbone 3.0% 8.4% 0.44MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures
Download full validation reportDownload
PDB entries from 2020-12-02