Cryo-EM structure of the CMV-stalled human 80S ribosome (Structure ii)

This is a large structure.

Summary for 6IP5

EMDB information9699 9701 9702 9703 9704
Descriptor28S ribosomal RNA, 5S ribosomal RNA, 5.8S ribosomal RNA, ... (83 entities in total)
Functional Keywordsribosome, translation
Biological sourceHomo sapiens (Human)
Total number of polymer chains84
Total molecular weight3857099.05
Yokoyama, T.,Shigematsu, H.,Shirouzu, M.,Imataka, H.,Ito, T. (deposition date: 2018-11-02, release date: 2019-05-29)
Primary citation
Yokoyama, T.,Machida, K.,Iwasaki, W.,Shigeta, T.,Nishimoto, M.,Takahashi, M.,Sakamoto, A.,Yonemochi, M.,Harada, Y.,Shigematsu, H.,Shirouzu, M.,Tadakuma, H.,Imataka, H.,Ito, T.
HCV IRES Captures an Actively Translating 80S Ribosome.
Mol.Cell, 2019
PubMed: 31080011 (PDB entries with the same primary citation)
DOI: 10.1016/j.molcel.2019.04.022
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliersRNA backbone7 0.2% 0.2% 0.41MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures

More Asymmetric unit images

Molmil generated image of 6ip5
no rotation
Molmil generated image of 6ip5
rotated about x axis by 90°
Molmil generated image of 6ip5
rotated about y axis by 90°