3JCM

Cryo-EM structure of the spliceosomal U4/U6.U5 tri-snRNP

Summary for 3JCM

• Entry DOI: 10.2210/pdb3jcm/pdb
• EMDB information: 6561
• Descriptor: Pre-mRNA-splicing factor 8, Small nuclear ribonucleoprotein Sm D3, Small nuclear ribonucleoprotein-associated protein B, ... (29 entities in total)
• Functional Keywords: u4/u6.u5 tri-snrnp, pre-mrna, transcription
• Biological source: Saccharomyces cerevisiae S288c; More
• Total number of polymer chains: 34
• Total formula weight: 1373832.70

Authors

Wan, R.,Yan, C.,Bai, R.,Wang, L.,Huang, M.,Wong, C.C.,Shi, Y. (deposition date: 2015-12-23, release date: 2016-02-24, Last modification date: 2024-03-20)

• Primary citation: Wan, R.,Yan, C.,Bai, R.,Wang, L.,Huang, M.,Wong, C.C.,Shi, Y.; The 3.8 angstrom structure of the U4/U6.U5 tri-snRNP: Insights into spliceosome assembly and catalysis; Science, 351:466-475, 2016; PubMed: 26743623; DOI: 10.1126/science.aad6466

Experimental method

ELECTRON MICROSCOPY (3.8 Å)