Rhodopsin-Gi complex

Summary for 6CMO

EMDB information7517
Descriptorchimera protein of Soluble cytochrome b562 and Rhodopsin, Guanine nucleotide-binding protein G(i) subunit alpha-1, Guanine nucleotide-binding protein G(I)/G(S)/G(T) subunit beta-1, ... (7 entities in total)
Functional Keywordsrhodopsin; g protein; cryo-em; structure, signaling protein
Biological sourceEscherichia coli
Total number of polymer chains6
Total molecular weight187781.72
Primary citation
Kang, Y.,Kuybeda, O.,de Waal, P.W.,Mukherjee, S.,Van Eps, N.,Dutka, P.,Zhou, X.E.,Bartesaghi, A.,Erramilli, S.,Morizumi, T.,Gu, X.,Yin, Y.,Liu, P.,Jiang, Y.,Meng, X.,Zhao, G.,Melcher, K.,Ernst, O.P.,Kossiakoff, A.A.,Subramaniam, S.,Xu, H.E.
Cryo-EM structure of human rhodopsin bound to an inhibitory G protein.
Nature, 558:553-558, 2018
PubMed: 29899450 (PDB entries with the same primary citation)
DOI: 10.1038/s41586-018-0215-y
MImport into Mendeley
Experimental method

Structure validation

ClashscoreRamachandran outliersSidechain outliers40 0.6%MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures
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PDB entries from 2020-09-16