9FCJ
| USP1 bound to ML323 and ubiquitin conjugated to FANCD2 (ordered subset, focused refinement) | Descriptor: | 5-methyl-2-(2-propan-2-ylphenyl)-~{N}-[[4-(1,2,3-triazol-1-yl)phenyl]methyl]pyrimidin-4-amine, Polyubiquitin-C, Ubiquitin carboxyl-terminal hydrolase 1, ... | Authors: | Rennie, M.L, Gundogdu, M, Walden, H. | Deposit date: | 2024-05-15 | Release date: | 2024-09-04 | Last modified: | 2024-09-25 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Structural and Biochemical Insights into the Mechanism of Action of the Clinical USP1 Inhibitor, KSQ-4279. J.Med.Chem., 67, 2024
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1F9J
| STRUCTURE OF A NEW CRYSTAL FORM OF TETRAUBIQUITIN | Descriptor: | TETRAUBIQUITIN | Authors: | Phillips, C.L, Thrower, J, Pickart, C.M, Hill, C.P. | Deposit date: | 2000-07-10 | Release date: | 2001-02-07 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structure of a new crystal form of tetraubiquitin. Acta Crystallogr.,Sect.D, 57, 2001
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3O65
| Crystal structure of a Josephin-ubiquitin complex: Evolutionary restraints on ataxin-3 deubiquitinating activity | Descriptor: | Putative ataxin-3-like protein, SODIUM ION, Ubiquitin | Authors: | Weeks, S.D, Grasty, K.C, Hernandez-Cuebas, L, Loll, P.J. | Deposit date: | 2010-07-28 | Release date: | 2010-11-24 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal Structure of a Josephin-Ubiquitin Complex: EVOLUTIONARY RESTRAINTS ON ATAXIN-3 DEUBIQUITINATING ACTIVITY. J.Biol.Chem., 286, 2011
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3JSV
| Crystal structure of mouse NEMO CoZi in complex with Lys63-linked di-ubiquitin | Descriptor: | NF-kappa-B essential modulator, Ubiquitin | Authors: | Yoshikawa, A, Sato, Y, Mimura, H, Yamashita, M, Yamagata, A, Fukai, S. | Deposit date: | 2009-09-11 | Release date: | 2009-10-27 | Last modified: | 2021-11-10 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Crystal structure of the NEMO ubiquitin-binding domain in complex with Lys 63-linked di-ubiquitin Febs Lett., 583, 2009
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2HTH
| Structural basis for ubiquitin recognition by the human EAP45/ESCRT-II GLUE domain | Descriptor: | Ubiquitin, Vacuolar protein sorting protein 36 | Authors: | Alam, S.L, Whitby, F.G, Hill, C.P, Sundquist, W.I. | Deposit date: | 2006-07-25 | Release date: | 2006-10-24 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural basis for ubiquitin recognition by the human ESCRT-II EAP45 GLUE domain. Nat.Struct.Mol.Biol., 13, 2006
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3DVN
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3MTN
| Usp21 in complex with a ubiquitin-based, USP21-specific inhibitor | Descriptor: | CHLORIDE ION, GLYCEROL, UBIQUITIN VARIANT UBV.21.4, ... | Authors: | Walker, J.R, Avvakumov, G.V, Xue, S, Li, Y, Ernst, A, Sidhu, S, Weigelt, J, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | Deposit date: | 2010-04-30 | Release date: | 2010-06-09 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | A strategy for modulation of enzymes in the ubiquitin system. Science, 339, 2013
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3PTF
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7BXG
| MavC-UBE2N-Ub complex | Descriptor: | MavC, Polyubiquitin-C, Ubiquitin-conjugating enzyme E2 N | Authors: | Gao, P, Wang, Y. | Deposit date: | 2020-04-19 | Release date: | 2020-05-20 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.705 Å) | Cite: | Insights into catalysis and regulation of non-canonical ubiquitination and deubiquitination by bacterial deamidase effectors. Nat Commun, 11, 2020
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4MM3
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3VFK
| The structure of monodechloro-teicoplanin in complex with its ligand, using ubiquitin as a ligand carrier | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-amino-2-deoxy-beta-D-glucopyranose, 8-METHYLNONANOIC ACID, ... | Authors: | Economou, N.J, Weeks, S.D, Grasty, K.C, Loll, P.J. | Deposit date: | 2012-01-09 | Release date: | 2013-01-09 | Last modified: | 2023-12-06 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structure of the complex between teicoplanin and a bacterial cell-wall peptide: use of a carrier-protein approach. Acta Crystallogr.,Sect.D, 69, 2013
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3IHP
| Covalent Ubiquitin-Usp5 Complex | Descriptor: | CHLORIDE ION, ETHANAMINE, Ubiquitin, ... | Authors: | Walker, J.R, Avvakumov, G.V, Xue, S, Butler-Cole, C, Weigelt, J, Bountra, C, Arrowsmith, C.H, Edwards, A.M, Bochkarev, A, Dhe-Paganon, S, Structural Genomics Consortium (SGC) | Deposit date: | 2009-07-30 | Release date: | 2009-12-29 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Covalent Ubiquitin-Usp5 Complex To be Published
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8A9J
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6UMP
| Crystal structure of MavC in complex with substrate mimic in P65 space group | Descriptor: | MavC, Ubiquitin, Ubiquitin-conjugating enzyme E2 N | Authors: | Puvar, K, Iyer, S, Luo, Z.Q, Das, C. | Deposit date: | 2019-10-10 | Release date: | 2020-05-27 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Legionella effector MavC targets the Ube2N~Ub conjugate for noncanonical ubiquitination. Nat Commun, 11, 2020
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6S53
| Crystal structure of TRIM21 RING domain in complex with an isopeptide-linked Ube2N~ubiquitin conjugate | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, E3 ubiquitin-protein ligase TRIM21, Polyubiquitin-C, ... | Authors: | Kiss, L, Boland, A, Neuhaus, D, James, L.C. | Deposit date: | 2019-06-30 | Release date: | 2019-09-11 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | A tri-ionic anchor mechanism drives Ube2N-specific recruitment and K63-chain ubiquitination in TRIM ligases. Nat Commun, 10, 2019
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3K9P
| The crystal structure of E2-25K and ubiquitin complex | Descriptor: | Ubiquitin, Ubiquitin-conjugating enzyme E2 K | Authors: | Kang, G.B, Ko, S, Song, S.M, Lee, W, Eom, S.H. | Deposit date: | 2009-10-16 | Release date: | 2010-09-08 | Last modified: | 2024-03-20 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural basis of E2-25K/UBB+1 interaction leading to proteasome inhibition and neurotoxicity J.Biol.Chem., 285, 2010
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7R71
| Crystal Structure of the UbArk2C-UbcH5b~Ub complex | Descriptor: | Ubiquitin, Ubiquitin,E3 ubiquitin-protein ligase RNF165, Ubiquitin-conjugating enzyme E2 D2, ... | Authors: | Paluda, A, Middleton, A.J, Mace, P.D, Day, C.L. | Deposit date: | 2021-06-24 | Release date: | 2022-03-09 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Ubiquitin and a charged loop regulate the ubiquitin E3 ligase activity of Ark2C. Nat Commun, 13, 2022
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7UYH
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3KVF
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5OHV
| K33-specific affimer bound to K33 diUb | Descriptor: | GLYCEROL, K33-specific affimer, SULFATE ION, ... | Authors: | Michel, M.A, Komander, D. | Deposit date: | 2017-07-18 | Release date: | 2017-10-04 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.801 Å) | Cite: | Ubiquitin Linkage-Specific Affimers Reveal Insights into K6-Linked Ubiquitin Signaling. Mol. Cell, 68, 2017
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7NPI
| Crystal structure of Mindy2 (C266A) in complex with Lys48-linked penta-ubiquitin (K48-Ub5) | Descriptor: | CHLORIDE ION, Polyubiquitin-C, SODIUM ION, ... | Authors: | Lange, S.M, Armstrong, L.A, Kulathu, Y. | Deposit date: | 2021-02-26 | Release date: | 2021-09-15 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.81 Å) | Cite: | Mechanism of activation and regulation of deubiquitinase activity in MINDY1 and MINDY2. Mol.Cell, 81, 2021
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4KSL
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3KW5
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5ZQ7
| SidE-Ubi-NAD | Descriptor: | ADENOSINE MONOPHOSPHATE, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SidE, ... | Authors: | Wang, Y, Gao, A, Gao, P. | Deposit date: | 2018-04-17 | Release date: | 2018-05-23 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.847 Å) | Cite: | Structural Insights into Non-canonical Ubiquitination Catalyzed by SidE. Cell, 173, 2018
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5E6J
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