5E6J

Structure of SARS PLpro bound to a Lys48-linked di-ubiquitin activity based probe

Summary for 5E6J

• Entry DOI: 10.2210/pdb5e6j/pdb
• Descriptor: Replicase polyprotein 1ab, ubiquitin, Polyubiquitin-B, ... (6 entities in total)
• Functional Keywords: sars plpro, deubiquitinating enzyme, ubiquitin, activity based probe, k48-linkage, hydrolase
• Biological source: Human SARS coronavirus (SARS-CoV); More
• Total number of polymer chains: 6
• Total formula weight: 107784.14

Authors

Lima, C.D.,Bekes, M. (deposition date: 2015-10-09, release date: 2016-05-18, Last modification date: 2023-11-15)

• Primary citation: Bekes, M.,van der Heden van Noort, G.J.,Ekkebus, R.,Ovaa, H.,Huang, T.T.,Lima, C.D.; Recognition of Lys48-Linked Di-ubiquitin and Deubiquitinating Activities of the SARS Coronavirus Papain-like Protease.; Mol. Cell, 62:572-585, 2016; PubMed: 27203180; DOI: 10.1016/j.molcel.2016.04.016

Experimental method

X-RAY DIFFRACTION (2.85 Å)