3O65

Crystal structure of a Josephin-ubiquitin complex: Evolutionary restraints on ataxin-3 deubiquitinating activity

Summary for 3O65

DescriptorPutative ataxin-3-like protein, Ubiquitin, SODIUM ION, ... (4 entities in total)
Functional Keywordspapain-like fold, ubiquitin thiolesterase, hydrolase-protein binding complex, hydrolase/protein binding
Biological sourceHomo sapiens (human)
Cellular locationNucleus  Q9H3M9
Ubiquitin: Cytoplasm  P0CG47
Total number of polymer chains8
Total molecular weight123299.77
Authors
Weeks, S.D.,Grasty, K.C.,Hernandez-Cuebas, L.,Loll, P.J. (deposition date: 2010-07-28, release date: 2010-11-24, Last modification date: 2017-11-08)
Primary citation
Weeks, S.D.,Grasty, K.C.,Hernandez-Cuebas, L.,Loll, P.J.
Crystal Structure of a Josephin-Ubiquitin Complex: EVOLUTIONARY RESTRAINTS ON ATAXIN-3 DEUBIQUITINATING ACTIVITY.
J.Biol.Chem., 286:4555-4565, 2011
PubMed: 21118805 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M110.177360
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.7 Å)
NMR Information
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.222120.9%1.0%4.8%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report