Crystal structure of K63-specific fab Apu2.16 bound to K63-linked di-ubiquitin

Summary for 3DVN

DescriptorHuman IgG1 fab fragment light chain, Human IgG1 fab fragment heavy chain, Ubiquitin D77, ... (4 entities in total)
Functional Keywordsdi-ubiquitin, fab fragment, antibody, nucleus, phosphoprotein, ribosomal rotein, immune system
Biological sourceHomo sapiens (Human)
Total number of polymer chains8
Total molecular weight132197.97
Hymowitz, S.G. (deposition date: 2008-07-18, release date: 2008-09-30, Last modification date: 2011-07-13)
Primary citation
Newton, K.,Matsumoto, M.L.,Wertz, I.E.,Kirkpatrick, D.S.,Lill, J.R.,Tan, J.,Dugger, D.,Gordon, N.,Sidhu, S.S.,Fellouse, F.A.,Komuves, L.,French, D.M.,Ferrando, R.E.,Lam, C.,Compaan, D.,Yu, C.,Bosanac, I.,Hymowitz, S.G.,Kelley, R.F.,Dixit, V.M.
Ubiquitin chain editing revealed by polyubiquitin linkage-specific antibodies.
Cell(Cambridge,Mass.), 134:668-678, 2008
PubMed: 18724939 (PDB entries with the same primary citation)
DOI: 10.1016/j.cell.2008.07.039
MImport into Mendeley
Experimental method
NMR Information

Structure validation

ClashscoreRamachandran outliersSidechain outliersRSRZ outliers60.7%6.8%7.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report