Crystal structure of mouse NEMO CoZi in complex with Lys63-linked di-ubiquitin

Summary for 3JSV

Related3F89 2ZVO 2ZVN 3FX0
DescriptorUbiquitin, NF-kappa-B essential modulator, ... (4 entities in total)
Functional Keywordsubiquitin, coiled-coil, cellular signaling, cytoplasm, isopeptide bond, nucleus, phosphoprotein, ubl conjugation, coiled coil, disulfide bond, metal-binding, transcription, transcription regulation, zinc, zinc-finger, signaling protein-transcription complex, signaling protein/transcription
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm (By similarity) O88522
Total number of polymer chains4
Total molecular weight39508.04
Yoshikawa, A.,Sato, Y.,Mimura, H.,Yamashita, M.,Yamagata, A.,Fukai, S. (deposition date: 2009-09-11, release date: 2009-10-27, Last modification date: 2011-07-13)
Primary citation
Yoshikawa, A.,Sato, Y.,Yamashita, M.,Mimura, H.,Yamagata, A.,Fukai, S.
Crystal structure of the NEMO ubiquitin-binding domain in complex with Lys 63-linked di-ubiquitin
Febs Lett., 583:3317-3322, 2009
PubMed: 19766637 (PDB entries with the same primary citation)
DOI: 10.1016/j.febslet.2009.09.028
MImport into Mendeley
Experimental method
NMR Information

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.294291.6%5.2%6.5%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report