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3JSV

Crystal structure of mouse NEMO CoZi in complex with Lys63-linked di-ubiquitin

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Ubiquitinpolymer768604.81UniProt (P62988)
Pfam (PF00240)
UniProt (by SIFTS) (P0CG48)
Homo sapiens (human)
2B
(B)
Ubiquitinpolymer778691.91UniProt (P62988)
Pfam (PF00240)
UniProt (by SIFTS) (P0CG48)
Homo sapiens (human)
3C, D
(C, D)
NF-kappa-B essential modulatorpolymer9411105.62UniProt (O88522)
Pfam (PF16516)
Mus musculus (mouse)NEMO, NF-kappa-B essential modifier, Inhibitor of nuclear factor kappa-B kinase subunit gamma, IkB kinase subunit gamma, I-kappa-B kinase gamma, IKK-gamma, IKKG, IkB kinase-associated protein 1, IKKAP1, mFIP-3
4E, F, G, H
(A, B, C, D)
waterwater18.026Chemie (HOH)
Sequence modifications
A: 1 - 76 (UniProt: P62988)
PDBExternal DatabaseDetails
Arg 63Lys 63engineered mutation
B: 1 - 76 (UniProt: P62988)
PDBExternal DatabaseDetails
Asp 77-engineered mutation
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains4
Total formula weight39508.0
All*Total formula weight39508.0
*Water molecules are not included.

227561

PDB entries from 2024-11-20

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