4KSL

Gumby/Fam105B in complex with linear di-ubiquitin

Summary for 4KSL

Related4KSJ 4KSK
DescriptorProtein FAM105B, Polyubiquitin-C (2 entities in total)
Functional Keywordsotu domain, deubiquitinase, linear diubiquitin, hydrolase
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm  Q96BN8
Ubiquitin: Cytoplasm  P0CG48
Total number of polymer chains24
Total molecular weight593925.32
Authors
Juang, Y.-C.,Ceccarelli, D.F.,Sicheri, F. (deposition date: 2013-05-17, release date: 2013-06-05, Last modification date: 2014-11-12)
Primary citation
Rivkin, E.,Almeida, S.M.,Ceccarelli, D.F.,Juang, Y.C.,MacLean, T.A.,Srikumar, T.,Huang, H.,Dunham, W.H.,Fukumura, R.,Xie, G.,Gondo, Y.,Raught, B.,Gingras, A.C.,Sicheri, F.,Cordes, S.P.
The linear ubiquitin-specific deubiquitinase gumby regulates angiogenesis.
Nature, 498:318-324, 2013
PubMed: 23708998 (PDB entries with the same primary citation)
DOI: 10.1038/nature12296
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.83 Å)
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Structure validation

ClashscoreRamachandran outliersSidechain outliers80.1%5.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report