Structural basis for ubiquitin recognition by the human EAP45/ESCRT-II GLUE domain

Summary for 2HTH

DescriptorUbiquitin, Vacuolar protein sorting protein 36 (2 entities in total)
Functional Keywordsglue domain, ph domain, protein sorting, viral budding, ubiquitin complex, protein transport
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm Q86VN1
Total number of polymer chains2
Total molecular weight24834.48
Alam, S.L.,Whitby, F.G.,Hill, C.P.,Sundquist, W.I. (deposition date: 2006-07-25, release date: 2006-10-24, Last modification date: 2017-10-18)
Primary citation
Alam, S.L.,Langelier, C.,Whitby, F.G.,Koirala, S.,Robinson, H.,Hill, C.P.,Sundquist, W.I.
Structural basis for ubiquitin recognition by the human ESCRT-II EAP45 GLUE domain.
Nat.Struct.Mol.Biol., 13:1029-1030, 2006
PubMed: 17057716 (PDB entries with the same primary citation)
DOI: 10.1038/nsmb1160
MImport into Mendeley
Experimental method
NMR Information

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.29346.6%2.7%1.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report