3RII
| Crystal structure of the catalytic domain of UCHL5, a proteasome-associated human deubiquitinating enzyme, reveals an unproductive form of the enzyme | Descriptor: | 1,2-ETHANEDIOL, MAGNESIUM ION, Ubiquitin carboxyl-terminal hydrolase isozyme L5 | Authors: | Das, C. | Deposit date: | 2011-04-13 | Release date: | 2011-11-09 | Last modified: | 2011-12-14 | Method: | X-RAY DIFFRACTION (2.0008 Å) | Cite: | Crystal structure of the catalytic domain of UCHL5, a proteasome-associated human deubiquitinating enzyme, reveals an unproductive form of the enzyme. Febs J., 278, 2011
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3RIS
| Crystal structure of the catalytic domain of UCHL5, a proteasome-associated human deubiquitinating enzyme, reveals an unproductive form of the enzyme | Descriptor: | GLYCEROL, SULFATE ION, Ubiquitin carboxyl-terminal hydrolase isozyme L5 | Authors: | Das, C, Permaul, M, Maiti, T.K. | Deposit date: | 2011-04-14 | Release date: | 2011-11-09 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.398 Å) | Cite: | Crystal structure of the catalytic domain of UCHL5, a proteasome-associated human deubiquitinating enzyme, reveals an unproductive form of the enzyme. Febs J., 278, 2011
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3IFW
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2ETL
| Crystal Structure of Ubiquitin Carboxy-terminal Hydrolase L1 (UCH-L1) | Descriptor: | CHLORIDE ION, Ubiquitin carboxyl-terminal hydrolase isozyme L1 | Authors: | Das, C, Hoang, Q.Q, Kreinbring, C.A, Luchansky, S.J, Meray, R.K, Ray, S.S, Lansbury, P.T, Ringe, D, Petsko, G.A. | Deposit date: | 2005-10-27 | Release date: | 2006-03-28 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Structural basis for conformational plasticity of the Parkinson's disease-associated ubiquitin hydrolase UCH-L1. Proc.Natl.Acad.Sci.USA, 103, 2006
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4IG7
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181D
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180D
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6MEP
| Crystal structure of the catalytic domain of the proto-oncogene tyrosine-protein kinase MER in complex with inhibitor UNC3437 | Descriptor: | CHLORIDE ION, MAGNESIUM ION, Tyrosine-protein kinase Mer, ... | Authors: | Da, C, Zhang, D, Stashko, M.A, Cheng, A, Hunter, D, Norris-Drouin, J, Graves, L, Machius, M, Miley, M.J, DeRyckere, D, Earp, H.S, Graham, D.K, Frye, S.V, Wang, X, Kireev, D. | Deposit date: | 2018-09-06 | Release date: | 2019-09-11 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.893 Å) | Cite: | Data-Driven Construction of Antitumor Agents with Controlled Polypharmacology. J.Am.Chem.Soc., 141, 2019
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1DE7
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1XPT
| BOVINE RIBONUCLEASE A (PHOSPHATE-FREE) | Descriptor: | RIBONUCLEASE A | Authors: | Sadasivan, C, Nagendra, H.G, Vijayan, M. | Deposit date: | 1998-02-23 | Release date: | 1998-05-27 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Plasticity, hydration and accessibility in ribonuclease A. The structure of a new crystal form and its low-humidity variant. Acta Crystallogr.,Sect.D, 54, 1998
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1XPS
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3RU0
| Cocrystal structure of human SMYD3 with inhibitor Sinefungin bound | Descriptor: | SET and MYND domain-containing protein 3, SINEFUNGIN, ZINC ION | Authors: | Foreman, K.W, Brown, M, Park, F, Emtage, S, Harriss, J, Das, C, Zhu, L, Crew, A, Arnold, L, Shaaban, S, Tucker, P. | Deposit date: | 2011-05-04 | Release date: | 2011-05-18 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.849 Å) | Cite: | Structural and Functional Profiling of the Human Histone Methyltransferase SMYD3. Plos One, 6, 2011
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3KVF
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3KW5
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6P5H
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6P5B
| Crystal Structure of MavC in Complex with Ub-UbE2N | Descriptor: | MavC, Ubiquitin, Ubiquitin-conjugating enzyme E2 N | Authors: | Puvar, K, Iyer, S, Negron Teron, K.I, Das, C. | Deposit date: | 2019-05-30 | Release date: | 2020-05-27 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.099 Å) | Cite: | Legionella effector MavC targets the Ube2N~Ub conjugate for noncanonical ubiquitination. Nat Commun, 11, 2020
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6WTG
| SdeA DUB Domain in complex with Ubiquitin | Descriptor: | Ubiquitin, Ubiquitinating/deubiquitinating enzyme SdeA | Authors: | Kenny, S, Sheedlo, M, Das, C. | Deposit date: | 2020-05-02 | Release date: | 2021-03-03 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.63 Å) | Cite: | Insights into Ubiquitin Product Release in Hydrolysis Catalyzed by the Bacterial Deubiquitinase SdeA. Biochemistry, 60, 2021
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6MRN
| Crystal Structure of ChlaDUB2 DUB domain | Descriptor: | Deubiquitinase and deneddylase Dub2 | Authors: | Hausman, J.M, Das, C. | Deposit date: | 2018-10-15 | Release date: | 2019-10-30 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.29 Å) | Cite: | The Two Deubiquitinating Enzymes fromChlamydia trachomatisHave Distinct Ubiquitin Recognition Properties. Biochemistry, 59, 2020
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6OAM
| Crystal Structure of ChlaDUB2 DUB domain | Descriptor: | Deubiquitinase and deneddylase Dub2, Ubiquitin | Authors: | Hausman, J.M, Das, C. | Deposit date: | 2019-03-17 | Release date: | 2020-04-22 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.503 Å) | Cite: | The Two Deubiquitinating Enzymes fromChlamydia trachomatisHave Distinct Ubiquitin Recognition Properties. Biochemistry, 59, 2020
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6OV1
| Structure of Staphylococcus aureus RNase P protein mutant with defective mRNA degradation activity | Descriptor: | Ribonuclease P protein component | Authors: | Ha, L, Colquhoun, J, Noinaj, N, Das, C, Dunman, P, Flaherty, D.P. | Deposit date: | 2019-05-06 | Release date: | 2020-12-02 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.66 Å) | Cite: | Genetic and biochemical characterization of Staphylococcus aureus RnpA To Be Published
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8DQF
| Crystal structure of Neisseria gonorrhoeae carbonic anhydrase with N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)cyclohexanecarboxamide | Descriptor: | Carbonic anhydrase, N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)cyclohexanecarboxamide, SULFATE ION, ... | Authors: | Marapaka, A.K, Das, C, Flaherty, D.P, Yadav, R. | Deposit date: | 2022-07-19 | Release date: | 2022-12-14 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Structural Characterization of Thiadiazolesulfonamide Inhibitors Bound to Neisseria gonorrhoeae alpha-Carbonic Anhydrase. Acs Med.Chem.Lett., 14, 2023
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8DYQ
| Crystal structure of Neisseria gonorrhoeae carbonic anhydrase with Acetazolamide | Descriptor: | 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, Carbonic anhydrase, SULFATE ION, ... | Authors: | Marapaka, A.K, Das, C, Flaherty, D.P, Yadav, R. | Deposit date: | 2022-08-04 | Release date: | 2022-12-14 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structural Characterization of Thiadiazolesulfonamide Inhibitors Bound to Neisseria gonorrhoeae alpha-Carbonic Anhydrase. Acs Med.Chem.Lett., 14, 2023
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8DR2
| Crystal structure of Neisseria gonorrhoeae carbonic anhydrase with 2-cyclohexyl-N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)acetamide | Descriptor: | 2-cyclohexyl-N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)acetamide, Carbonic anhydrase, SULFATE ION, ... | Authors: | Marapaka, A.K, Das, C, Flaherty, D.P, Yadav, R. | Deposit date: | 2022-07-20 | Release date: | 2022-12-14 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.81 Å) | Cite: | Structural Characterization of Thiadiazolesulfonamide Inhibitors Bound to Neisseria gonorrhoeae alpha-Carbonic Anhydrase. Acs Med.Chem.Lett., 14, 2023
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8DRB
| Crystal structure of Neisseria gonorrhoeae carbonic anhydrase with 3-phenyl-N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)propanamide | Descriptor: | 3-phenyl-N-(5-sulfamoyl-1,3,4-thiadiazol-2-yl)propanamide, Carbonic anhydrase, SULFATE ION, ... | Authors: | Marapaka, A.K, Das, C, Flaherty, D.P, Yadav, R. | Deposit date: | 2022-07-20 | Release date: | 2022-12-14 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.59 Å) | Cite: | Structural Characterization of Thiadiazolesulfonamide Inhibitors Bound to Neisseria gonorrhoeae alpha-Carbonic Anhydrase. Acs Med.Chem.Lett., 14, 2023
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8DPC
| Crystal structure of carbonic anhydrase from Neisseria gonorrhoeae | Descriptor: | Carbonic anhydrase, SULFATE ION, ZINC ION | Authors: | Marapaka, A.K, Das, C, Flaherty, D.P, Yadav, R. | Deposit date: | 2022-07-15 | Release date: | 2022-12-14 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (2.41 Å) | Cite: | Structural Characterization of Thiadiazolesulfonamide Inhibitors Bound to Neisseria gonorrhoeae alpha-Carbonic Anhydrase. Acs Med.Chem.Lett., 14, 2023
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