4IG7

Crystal structure of Trichinella spiralis UCH37 bound to Ubiquitin vinyl methyl ester

Summary for 4IG7

Related3IHR
DescriptorUbiquitin C-terminal hydrolase 37, Ubiquitin, METHYL 4-AMINOBUTANOATE, ... (4 entities in total)
Functional Keywordshelix-beta-helix sandwich, deubiquitination, ubiquitin c-terminal hydrolase, cytosol, hydrolase-signaling protein complex, hydrolase/signaling protein
Biological sourceTrichinella spiralis
More
Cellular locationUbiquitin: Cytoplasm (By similarity) P0CG48
Total number of polymer chains2
Total molecular weight47447.65
Authors
Das, C.,Kim, M.I.,Morrow, M.E. (deposition date: 2012-12-16, release date: 2013-05-29, Last modification date: 2014-01-15)
Primary citation
Morrow, M.E.,Kim, M.-I.,Ronau, J.A.,Sheedlo, M.J.,White, R.R.,Chaney, J.,Paul, L.N.,Lill, M.A.,Artavanis-Tsakonas, K.,Das, C.
Stabilization of an Unusual Salt Bridge in Ubiquitin by the Extra C‑Terminal Domain of the Proteasome-Associated Deubiquitinase UCH37 as a Mechanism of Its Exo Specificity.
Biochemistry, 52:3564-3578, 2013
PubMed: 23617878 (PDB entries with the same primary citation)
DOI: 10.1021/bi4003106
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (1.996 Å)
?

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.24061.0%6.4%6.2%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report