3RU0

Cocrystal structure of human SMYD3 with inhibitor Sinefungin bound

Summary for 3RU0

Entry DOI	10.2210/pdb3ru0/pdb
Descriptor	SET and MYND domain-containing protein 3, SINEFUNGIN, ZINC ION, ... (4 entities in total)
Functional Keywords	methyltransferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor
Biological source	Homo sapiens (human)
Cellular location	Cytoplasm: Q9H7B4
Total number of polymer chains	2
Total formula weight	101853.99
Authors	Foreman, K.W.,Brown, M.,Park, F.,Emtage, S.,Harriss, J.,Das, C.,Zhu, L.,Crew, A.,Arnold, L.,Shaaban, S.,Tucker, P. (deposition date: 2011-05-04, release date: 2011-05-18, Last modification date: 2024-02-28)
Primary citation	Foreman, K.W.,Brown, M.,Park, F.,Emtage, S.,Harriss, J.,Das, C.,Zhu, L.,Crew, A.,Arnold, L.,Shaaban, S.,Tucker, P. Structural and Functional Profiling of the Human Histone Methyltransferase SMYD3. Plos One, 6:e22290-e22290, 2011 Cited by PubMed: 21779408 DOI: 10.1371/journal.pone.0022290 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.849 Å)

Structure validation