3RU0
Cocrystal structure of human SMYD3 with inhibitor Sinefungin bound
Summary for 3RU0
Entry DOI | 10.2210/pdb3ru0/pdb |
Descriptor | SET and MYND domain-containing protein 3, SINEFUNGIN, ZINC ION, ... (4 entities in total) |
Functional Keywords | methyltransferase, transferase-transferase inhibitor complex, transferase/transferase inhibitor |
Biological source | Homo sapiens (human) |
Cellular location | Cytoplasm: Q9H7B4 |
Total number of polymer chains | 2 |
Total formula weight | 101853.99 |
Authors | Foreman, K.W.,Brown, M.,Park, F.,Emtage, S.,Harriss, J.,Das, C.,Zhu, L.,Crew, A.,Arnold, L.,Shaaban, S.,Tucker, P. (deposition date: 2011-05-04, release date: 2011-05-18, Last modification date: 2024-02-28) |
Primary citation | Foreman, K.W.,Brown, M.,Park, F.,Emtage, S.,Harriss, J.,Das, C.,Zhu, L.,Crew, A.,Arnold, L.,Shaaban, S.,Tucker, P. Structural and Functional Profiling of the Human Histone Methyltransferase SMYD3. Plos One, 6:e22290-e22290, 2011 Cited by PubMed: 21779408DOI: 10.1371/journal.pone.0022290 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (1.849 Å) |
Structure validation
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