8DYQ

Crystal structure of Neisseria gonorrhoeae carbonic anhydrase with Acetazolamide

Summary for 8DYQ

Entry DOI	10.2210/pdb8dyq/pdb
Descriptor	Carbonic anhydrase, 5-ACETAMIDO-1,3,4-THIADIAZOLE-2-SULFONAMIDE, ZINC ION, ... (5 entities in total)
Functional Keywords	carbonic anhydrase, neisseria gonorrhoeae, acetazolamide, lyase
Biological source	Neisseria gonorrhoeae
Total number of polymer chains	4
Total formula weight	111182.03
Authors	Marapaka, A.K.,Das, C.,Flaherty, D.P.,Yadav, R. (deposition date: 2022-08-04, release date: 2022-12-14, Last modification date: 2023-10-25)
Primary citation	Marapaka, A.K.,Nocentini, A.,Youse, M.S.,An, W.,Holly, K.J.,Das, C.,Yadav, R.,Seleem, M.N.,Supuran, C.T.,Flaherty, D.P. Structural Characterization of Thiadiazolesulfonamide Inhibitors Bound to Neisseria gonorrhoeae alpha-Carbonic Anhydrase. Acs Med.Chem.Lett., 14:103-109, 2023 Cited by PubMed: 36655133 DOI: 10.1021/acsmedchemlett.2c00471 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.15 Å)

Structure validation