3RII

Crystal structure of the catalytic domain of UCHL5, a proteasome-associated human deubiquitinating enzyme, reveals an unproductive form of the enzyme

Summary for 3RII

• Entry DOI: 10.2210/pdb3rii/pdb
• Related: 3IHR
• Descriptor: Ubiquitin carboxyl-terminal hydrolase isozyme L5, 1,2-ETHANEDIOL, MAGNESIUM ION, ... (4 entities in total)
• Functional Keywords: alpha-beta-alpha fold, thiol hydroalse, cysteine protease, deubiquitinating enzyme, ubiquitin hydrolase, hydrolase
• Biological source: Homo sapiens (human)
• Cellular location: Cytoplasm: Q9Y5K5
• Total number of polymer chains: 2
• Total formula weight: 52808.16

Authors

Das, C. (deposition date: 2011-04-13, release date: 2011-11-09, Last modification date: 2011-12-14)

• Primary citation: Maiti, T.K.,Permaul, M.,Boudreaux, D.A.,Mahanic, C.,Mauney, S.,Das, C.; Crystal structure of the catalytic domain of UCHL5, a proteasome-associated human deubiquitinating enzyme, reveals an unproductive form of the enzyme.; Febs J., 278:4917-4926, 2011; PubMed: 21995438; DOI: 10.1111/j.1742-4658.2011.08393.x

Experimental method

X-RAY DIFFRACTION (2.0008 Å)