3K9P

The crystal structure of E2-25K and ubiquitin complex

Summary for 3K9P

Related3K9O
DescriptorUbiquitin-conjugating enzyme E2 K, Ubiquitin (2 entities in total)
Functional Keywordse2-25k, ubiquitin, complex structure, atp-binding, isopeptide bond, ligase, nucleotide-binding, ubl conjugation pathway, nucleus, phosphoprotein, ligase-signaling protein complex, ligase/signaling protein
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm (By similarity) P61086
Total number of polymer chains2
Total molecular weight32953.57
Authors
Kang, G.B.,Ko, S.,Song, S.M.,Lee, W.,Eom, S.H. (deposition date: 2009-10-16, release date: 2010-09-08, Last modification date: 2011-07-13)
Primary citation
Ko, S.,Kang, G.B.,Song, S.M.,Lee, J.-G.,Shin, D.Y.,Yun, J.-H.,Sheng, Y.,Cheong, C.,Jeon, Y.H.,Jung, Y.-K.,Arrowsmith, C.H.,Avvakumov, G.V.,Dhe-Paganon, S.,Yoo, Y.J.,Eom, S.H.,Lee, W.
Structural basis of E2-25K/UBB+1 interaction leading to proteasome inhibition and neurotoxicity
J.Biol.Chem., 285:36070-36080, 2010
PubMed: 20826778 (PDB entries with the same primary citation)
DOI: 10.1074/jbc.M110.145219
MImport into Mendeley
Experimental method
X-RAY DIFFRACTION (2.8 Å)
NMR Information
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Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.253263.7%11.9%0MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report