The crystal structure of E2-25K and UBB+1 complex

Summary for 3K9O

DescriptorUbiquitin-conjugating enzyme E2 K, Ubiquitin (3 entities in total)
Functional Keywordse2-25k, ubb+1, complex structure, atp-binding, isopeptide bond, ligase, nucleotide-binding, ubl conjugation pathway
Biological sourceHomo sapiens (human)
Cellular locationCytoplasm (By similarity) P61086
Total number of polymer chains2
Total molecular weight33314.77
Kang, G.B.,Ko, S.,Song, S.M.,Lee, W.,Eom, S.H. (deposition date: 2009-10-16, release date: 2010-09-08, Last modification date: 2011-07-13)
Primary citation
Kang, G.B.,Ko, S.,Song, S.M.,Lee, W.,Eom, S.M.
Structural Basis of E2-25K/UBB+1 Interaction for Neurotoxicity of Alzheimer Disease by Proteasome Inhibition
To be Published,
Experimental method
NMR Information

Structure validation

RfreeClashscoreRamachandran outliersSidechain outliersRSRZ outliers0.229301.7%2.6%MetricValuePercentile RanksWorseBetterPercentile relative to all X-ray structuresPercentile relative to X-ray structures of similar resolution
Download full validation report