PDB: 1515 件ウェブページステータス検索Chemie searchBIRD

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7B5L	Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: NEDD8-CUL1-RBX1-SKP1-SKP2-CKSHS1-Cyclin A-CDK2-p27-UBE2L3~Ub~ARIH1. Transition State 1 分子名称: 5-azanylpentan-2-one, Cullin-1, Cyclin-A2, ... 著者 Horn-Ghetko, D, Prabu, J.R, Schulman, B.A. 登録日 2020-12-04 公開日 2021-02-10 最終更新日 2021-03-10 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Ubiquitin ligation to F-box protein targets by SCF-RBR E3-E3 super-assembly. Nature, 590, 2021
7B5M	Ubiquitin ligation to F-box protein substrates by SCF-RBR E3-E3 super-assembly: CUL1-RBX1-SKP1-SKP2-CKSHS1-p27~Ub~ARIH1. Transition State 2 分子名称: Cullin-1, Cyclin-dependent kinase inhibitor 1B, Cyclin-dependent kinases regulatory subunit 1, ... 著者 Horn-Ghetko, D, Prabu, J.R, Schulman, B.A. 登録日 2020-12-05 公開日 2021-02-17 最終更新日 2021-03-10 実験手法 ELECTRON MICROSCOPY (3.91 Å) 主引用文献 Ubiquitin ligation to F-box protein targets by SCF-RBR E3-E3 super-assembly. Nature, 590, 2021
4V8M	High-resolution cryo-electron microscopy structure of the Trypanosoma brucei ribosome 分子名称: 18S RRNA OF THE SMALL RIBOSOMAL SUBUNIT, 40S RIBOSOMAL PROTEIN S10, PUTATIVE, ... 著者 Hashem, Y, des Georges, A, Fu, J, Buss, S.N, Jossinet, F, Jobe, A, Zhang, Q, Liao, H.Y, Grassucci, R.A, Bajaj, C, Westhof, E, Madison-Antenucci, S, Frank, J. 登録日 2012-12-09 公開日 2014-07-09 最終更新日 2019-12-11 実験手法 ELECTRON MICROSCOPY (5.57 Å) 主引用文献 High-Resolution Cryo-Electron Microscopy Structure of the Trypanosoma Brucei Ribosome. Nature, 494, 2013
7NWI	Mammalian pre-termination 80S ribosome with Empty-A site bound by Blasticidin S 分子名称: 18S ribosomal RNA, 28S ribosomal RNA+BlaS, 40S ribosomal protein S11, ... 著者 Powers, K.T, Yadav, S.K.N, Bufton, J.C, Schaffitzel, C. 登録日 2021-03-16 公開日 2021-07-07 最終更新日 2023-01-11 実験手法 ELECTRON MICROSCOPY (3.13 Å) 主引用文献 Blasticidin S inhibits mammalian translation and enhances production of protein encoded by nonsense mRNA. Nucleic Acids Res., 49, 2021
7NWG	Mammalian pre-termination 80S ribosome with Hybrid P/E- and A/P-site tRNA's bound by Blasticidin S. 分子名称: 18S Ribosomal RNA, 28S Ribosomal RNA, 40S ribosomal protein S10, ... 著者 Powers, K.T, Yadav, S.K.N, Bufton, J.C, Schaffitzel, C. 登録日 2021-03-16 公開日 2021-07-07 最終更新日 2023-01-11 実験手法 ELECTRON MICROSCOPY (3.8 Å) 主引用文献 Blasticidin S inhibits mammalian translation and enhances production of protein encoded by nonsense mRNA. Nucleic Acids Res., 49, 2021
3JVZ	E2~Ubiquitin-HECT 分子名称: E3 ubiquitin-protein ligase NEDD4-like, Ubiquitin, Ubiquitin-conjugating enzyme E2 D2 著者 Souphron, J, Kamadurai, H.B, Schulman, B.A. 登録日 2009-09-17 公開日 2010-01-12 最終更新日 2023-09-06 実験手法 X-RAY DIFFRACTION (3.3 Å) 主引用文献 Insights into ubiquitin transfer cascades from a structure of a UbcH5B approximately ubiquitin-HECT(NEDD4L) complex. Mol.Cell, 36, 2009
7NWH	Mammalian pre-termination 80S ribosome with eRF1 and eRF3 bound by Blasticidin S. 分子名称: 18S Ribosomal RNA, 28S Ribosomal RNA, 40S ribosomal protein S10, ... 著者 Powers, K.T, Yadav, S.K.N, Bufton, J.C, Schaffitzel, C. 登録日 2021-03-16 公開日 2021-07-07 最終更新日 2023-01-11 実験手法 ELECTRON MICROSCOPY (4.1 Å) 主引用文献 Blasticidin S inhibits mammalian translation and enhances production of protein encoded by nonsense mRNA. Nucleic Acids Res., 49, 2021
6P5N	Structure of a mammalian 80S ribosome in complex with a single translocated Israeli Acute Paralysis Virus IRES and eRF1 分子名称: 18S rRNA, 28S rRNA, 5.8S rRNA, ... 著者 Acosta-Reyes, F.J, Neupane, R, Frank, J, Fernandez, I.S. 登録日 2019-05-30 公開日 2019-09-25 最終更新日 2020-01-08 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs. Embo J., 38, 2019
7ASE	43S preinitiation complex from Trypanosoma cruzi with the kDDX60 helicase 分子名称: 18S, 40S ribosomal protein S10, putative, ... 著者 Bochler, A, Brito Querido, J, Prilepskaja, T, Soufari, H, Del Cistia, M.L, Kuhn, L, Rimoldi Ribeiro, A, Valasek, L.S, Hashem, Y. 登録日 2020-10-27 公開日 2021-04-14 最終更新日 2021-04-21 実験手法 ELECTRON MICROSCOPY (3.33 Å) 主引用文献 Structural Differences in Translation Initiation between Pathogenic Trypanosomatids and Their Mammalian Hosts. Cell Rep, 33, 2020
3J6Y	S. cerevisiae 80S ribosome bound with Taura syndrome virus (TSV) IRES, 2 degree rotation (Class I) 分子名称: 18S ribosomal RNA, 25S ribosomal RNA, 40S ribosomal protein S0, ... 著者 Koh, C.S, Brilot, A.F, Grigorieff, N, Korostelev, A.A. 登録日 2014-04-16 公開日 2014-06-11 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (6.1 Å) 主引用文献 Taura syndrome virus IRES initiates translation by binding its tRNA-mRNA-like structural element in the ribosomal decoding center. Proc.Natl.Acad.Sci.USA, 111, 2014
3K9P	The crystal structure of E2-25K and ubiquitin complex 分子名称: Ubiquitin, Ubiquitin-conjugating enzyme E2 K 著者 Kang, G.B, Ko, S, Song, S.M, Lee, W, Eom, S.H. 登録日 2009-10-16 公開日 2010-09-08 最終更新日 2024-03-20 実験手法 X-RAY DIFFRACTION (2.8 Å) 主引用文献 Structural basis of E2-25K/UBB+1 interaction leading to proteasome inhibition and neurotoxicity J.Biol.Chem., 285, 2010
3JAG	Structure of a mammalian ribosomal termination complex with ABCE1, eRF1(AAQ), and the UAA stop codon 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 5.8S ribosomal RNA, ... 著者 Brown, A, Shao, S, Murray, J, Hegde, R.S, Ramakrishnan, V. 登録日 2015-06-10 公開日 2015-08-12 最終更新日 2018-07-18 実験手法 ELECTRON MICROSCOPY (3.65 Å) 主引用文献 Structural basis for stop codon recognition in eukaryotes. Nature, 524, 2015
7AZY	Context-specific inhibition of eukaryotic translation by macrolide antibiotics 分子名称: 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... 著者 Koller, T.O, Wilson, D.N. 登録日 2020-11-17 公開日 2021-05-19 最終更新日 2024-07-10 実験手法 ELECTRON MICROSCOPY (2.877 Å) 主引用文献 Context-specific action of macrolide antibiotics on the eukaryotic ribosome. Nat Commun, 12, 2021
3J79	Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine, large subunit 分子名称: 28S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... 著者 Wong, W, Bai, X.C, Brown, A, Fernandez, I.S, Hanssen, E, Condron, M, Tan, Y.H, Baum, J, Scheres, S.H.W. 登録日 2014-06-02 公開日 2014-07-16 最終更新日 2024-02-21 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Cryo-EM structure of the Plasmodium falciparum 80S ribosome bound to the anti-protozoan drug emetine. Elife, 3, 2014
6P5B	Crystal Structure of MavC in Complex with Ub-UbE2N 分子名称: MavC, Ubiquitin, Ubiquitin-conjugating enzyme E2 N 著者 Puvar, K, Iyer, S, Negron Teron, K.I, Das, C. 登録日 2019-05-30 公開日 2020-05-27 最終更新日 2023-10-11 実験手法 X-RAY DIFFRACTION (2.099 Å) 主引用文献 Legionella effector MavC targets the Ube2N~Ub conjugate for noncanonical ubiquitination. Nat Commun, 11, 2020
6P5K	Structure of a mammalian 80S ribosome in complex with the Israeli Acute Paralysis Virus IRES (Class 3) 分子名称: 18S rRNA, 28S rRNA, 5.8S rRNA, ... 著者 Acosta-Reyes, F.J, Neupane, R, Frank, J, Fernandez, I.S. 登録日 2019-05-30 公開日 2019-09-18 最終更新日 2020-01-08 実験手法 ELECTRON MICROSCOPY (3.1 Å) 主引用文献 The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs. Embo J., 38, 2019
5XY3	Large subunit of Trichomonas vaginalis ribosome 分子名称: 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... 著者 Li, Z, Guo, Q, Zheng, L, Ji, Y, Xie, Y, Lai, D, Lun, Z, Suo, X, Gao, N. 登録日 2017-07-06 公開日 2017-08-30 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (3.2 Å) 主引用文献 Cryo-EM structures of the 80S ribosomes from human parasites Trichomonas vaginalis and Toxoplasma gondii Cell Res., 27, 2017
6G5I	Cryo-EM structure of a late human pre-40S ribosomal subunit - State R 分子名称: 18S ribosomal RNA, 40S ribosomal protein S10, 40S ribosomal protein S11, ... 著者 Ameismeier, M, Cheng, J, Berninghausen, O, Beckmann, R. 登録日 2018-03-29 公開日 2018-06-06 最終更新日 2024-05-15 実験手法 ELECTRON MICROSCOPY (3.5 Å) 主引用文献 Visualizing late states of human 40S ribosomal subunit maturation. Nature, 558, 2018
1FXT	STRUCTURE OF A CONJUGATING ENZYME-UBIQUITIN THIOLESTER COMPLEX 分子名称: UBIQUITIN, UBIQUITIN-CONJUGATING ENZYME E2-24 KDA 著者 Hamilton, K.S, Shaw, G.S, Williams, R.S, Huzil, J.T, McKenna, S, Ptak, C, Glover, M, Ellison, M.J. 登録日 2000-09-26 公開日 2001-10-10 最終更新日 2024-05-22 実験手法 SOLUTION NMR 主引用文献 Structure of a conjugating enzyme-ubiquitin thiolester intermediate reveals a novel role for the ubiquitin tail. Structure, 9, 2001
4UG0	STRUCTURE OF THE HUMAN 80S RIBOSOME 分子名称: 18S ribosomal RNA, 28S ribosomal RNA, 40S RIBOSOMAL PROTEIN, ... 著者 Khatter, H, Myasnikov, A.G, Natchiar, S.K, Klaholz, B.P. 登録日 2015-03-20 公開日 2015-06-10 最終更新日 2019-12-18 実験手法 ELECTRON MICROSCOPY (3.6 Å) 主引用文献 Structure of the human 80S ribosome NATURE, 520, 2015
8OYP	Crystal structure of Ubiquitin specific protease 11 (USP11) in complex with a substrate mimetic 分子名称: CADMIUM ION, CHLORIDE ION, GLYCEROL, ... 著者 Maurer, S.K, Caulton, S.G, Ward, S.J, Emsley, J, Dreveny, I. 登録日 2023-05-05 公開日 2023-10-18 最終更新日 2023-11-15 実験手法 X-RAY DIFFRACTION (2.44 Å) 主引用文献 Ubiquitin-specific protease 11 structure in complex with an engineered substrate mimetic reveals a molecular feature for deubiquitination selectivity. J.Biol.Chem., 299, 2023
8C83	Cryo-EM structure of in vitro reconstituted Otu2-bound Ub-40S complex 分子名称: 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S11-A, ... 著者 Ikeuchi, K, Buschauer, R, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. 登録日 2023-01-18 公開日 2023-05-24 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Molecular basis for recognition and deubiquitination of 40S ribosomes by Otu2. Nat Commun, 14, 2023
8CAH	Cryo-EM structure of native Otu2-bound ubiquitinated 43S pre-initiation complex 分子名称: 18S ribosomal RNA, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ... 著者 Ikeuchi, K, Buschauer, R, Cheng, J, Berninghausen, O, Becker, T, Beckmann, R. 登録日 2023-01-24 公開日 2023-05-24 実験手法 ELECTRON MICROSCOPY (3 Å) 主引用文献 Molecular basis for recognition and deubiquitination of 40S ribosomes by Otu2. Nat Commun, 14, 2023
8CH6	Structure of a late-stage activated spliceosome (BAqr) arrested with a dominant-negative Aquarius mutant (state B complex). 分子名称: 116 kDa U5 small nuclear ribonucleoprotein component, BUD13 homolog, Cell division cycle 5-like protein, ... 著者 Cretu, C, Schmitzova, J, Pena, V. 登録日 2023-02-07 公開日 2023-05-10 最終更新日 2024-07-24 実験手法 ELECTRON MICROSCOPY (5.9 Å) 主引用文献 Structural basis of catalytic activation in human splicing. Nature, 617, 2023
8OVA	CRYO-EM STRUCTURE OF TRYPANOSOMA BRUCEI PROCYCLIC FORM 80S RIBOSOME : PARENTAL STRAIN 分子名称: 40S ribosomal protein L14, putative, 40S ribosomal protein S10, ... 著者 Rajan, K.S, Yonath, A. 登録日 2023-04-25 公開日 2023-11-29 最終更新日 2024-04-24 実験手法 ELECTRON MICROSCOPY (2.47 Å) 主引用文献 A single pseudouridine on rRNA regulates ribosome structure and function in the mammalian parasite Trypanosoma brucei. Nat Commun, 14, 2023

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