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7NWI

Mammalian pre-termination 80S ribosome with Empty-A site bound by Blasticidin S

This is a non-PDB format compatible entry.
Summary for 7NWI
Entry DOI10.2210/pdb7nwi/pdb
EMDB information12633
DescriptorL8, Ribosomal protein L11, L13, ... (87 entities in total)
Functional Keywordsinhibitor 80s termination complex blasticidin s translation nmd, ribosome
Biological sourceOryctolagus cuniculus (Rabbit)
More
Total number of polymer chains84
Total formula weight3414474.92
Authors
Powers, K.T.,Yadav, S.K.N.,Bufton, J.C.,Schaffitzel, C. (deposition date: 2021-03-16, release date: 2021-07-07, Last modification date: 2023-01-11)
Primary citationPowers, K.T.,Stevenson-Jones, F.,Yadav, S.K.N.,Amthor, B.,Bufton, J.C.,Borucu, U.,Shen, D.,Becker, J.P.,Lavysh, D.,Hentze, M.W.,Kulozik, A.E.,Neu-Yilik, G.,Schaffitzel, C.
Blasticidin S inhibits mammalian translation and enhances production of protein encoded by nonsense mRNA.
Nucleic Acids Res., 49:7665-7679, 2021
Cited by
PubMed: 34157102
DOI: 10.1093/nar/gkab532
PDB entries with the same primary citation
Experimental method
ELECTRON MICROSCOPY (3.13 Å)
Structure validation

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