6P5K

Structure of a mammalian 80S ribosome in complex with the Israeli Acute Paralysis Virus IRES (Class 3)

This is a large structure.

Summary for 6P5K

Related6P5I 6P5J
EMDB information20255 20256 20257
Descriptor28S rRNA, 5S rRNA, 5.8S rRNA, ... (81 entities in total)
Functional Keywordsisraeli acute paralysis virus, internal ribosome entry site, ires, small ribosomal subunit, 40s, large ribosomal subunit, 60s, 80s, ribosomes, ribosome
Biological sourceIsraeli acute paralysis virus
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Total number of polymer chains81
Total molecular weight3412016.38
Authors
Acosta-Reyes, F.J.,Neupane, R.,Frank, J.,Fernandez, I.S. (deposition date: 2019-05-30, release date: 2019-09-18, Last modification date: 2020-01-08)
Primary citation
Acosta-Reyes, F.,Neupane, R.,Frank, J.,Fernandez, I.S.
The Israeli acute paralysis virus IRES captures host ribosomes by mimicking a ribosomal state with hybrid tRNAs.
Embo J., 38:e102226-e102226, 2019
PubMed: 31609474 (PDB entries with the same primary citation)
DOI: 10.15252/embj.2019102226
MImport into Mendeley
Experimental method
ELECTRON MICROSCOPY
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Structure validation

ClashscoreRamachandran outliersSidechain outliersRNA backbone3 0.6% 3.0% 0.44MetricValuePercentile RanksWorseBetterPercentile relative to all structuresPercentile relative to all EM structures
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168889
PDB entries from 2020-09-16