8CAH

Cryo-EM structure of native Otu2-bound ubiquitinated 43S pre-initiation complex

Summary for 8CAH

• Entry DOI: 10.2210/pdb8cah/pdb
• EMDB information: 16525
• Descriptor: Eukaryotic translation initiation factor 3 subunit I, 40S ribosomal protein S0-A, 40S ribosomal protein S1-A, ... (51 entities in total)
• Functional Keywords: ribosome, translation, ubiquitin, deubiquitinating enzyme, initiation, complex
• Biological source: Saccharomyces cerevisiae W303; More
• Total number of polymer chains: 48
• Total formula weight: 1743295.28

Authors

Ikeuchi, K.,Buschauer, R.,Cheng, J.,Berninghausen, O.,Becker, T.,Beckmann, R. (deposition date: 2023-01-24, release date: 2023-05-24)

• Primary citation: Ikeuchi, K.,Ivic, N.,Buschauer, R.,Cheng, J.,Frohlich, T.,Matsuo, Y.,Berninghausen, O.,Inada, T.,Becker, T.,Beckmann, R.; Molecular basis for recognition and deubiquitination of 40S ribosomes by Otu2.; Nat Commun, 14:2730-2730, 2023; PubMed: 37169754; DOI: 10.1038/s41467-023-38161-w

Experimental method

ELECTRON MICROSCOPY (3 Å)