8OYP

Crystal structure of Ubiquitin specific protease 11 (USP11) in complex with a substrate mimetic

Summary for 8OYP

Entry DOI	10.2210/pdb8oyp/pdb
Descriptor	Ubiquitin carboxyl-terminal hydrolase 11,Response regulator FrzS, Polyubiquitin-B, CADMIUM ION, ... (8 entities in total)
Functional Keywords	protease, ubiquitin, substrate complex, deubiquitinating enzyme, hydrolase
Biological source	Homo sapiens (human) More
Total number of polymer chains	4
Total formula weight	128747.73
Authors	Maurer, S.K.,Caulton, S.G.,Ward, S.J.,Emsley, J.,Dreveny, I. (deposition date: 2023-05-05, release date: 2023-10-18, Last modification date: 2023-11-15)
Primary citation	Maurer, S.K.,Mayer, M.P.,Ward, S.J.,Boudjema, S.,Halawa, M.,Zhang, J.,Caulton, S.G.,Emsley, J.,Dreveny, I. Ubiquitin-specific protease 11 structure in complex with an engineered substrate mimetic reveals a molecular feature for deubiquitination selectivity. J.Biol.Chem., 299:105300-105300, 2023 Cited by PubMed: 37777157 DOI: 10.1016/j.jbc.2023.105300 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.44 Å)

Structure validation