7NWH
Mammalian pre-termination 80S ribosome with eRF1 and eRF3 bound by Blasticidin S.
This is a non-PDB format compatible entry.
Summary for 7NWH
Entry DOI | 10.2210/pdb7nwh/pdb |
EMDB information | 12632 |
Descriptor | 60S ribosomal protein L8, eL29, 60S ribosomal protein L6, ... (88 entities in total) |
Functional Keywords | inhibitor 80s termination complex blasticidin s translation nmd, ribosome |
Biological source | Oryctolagus cuniculus (Rabbit) More |
Total number of polymer chains | 84 |
Total formula weight | 3476517.22 |
Authors | Powers, K.T.,Yadav, S.K.N.,Bufton, J.C.,Schaffitzel, C. (deposition date: 2021-03-16, release date: 2021-07-07, Last modification date: 2023-01-11) |
Primary citation | Powers, K.T.,Stevenson-Jones, F.,Yadav, S.K.N.,Amthor, B.,Bufton, J.C.,Borucu, U.,Shen, D.,Becker, J.P.,Lavysh, D.,Hentze, M.W.,Kulozik, A.E.,Neu-Yilik, G.,Schaffitzel, C. Blasticidin S inhibits mammalian translation and enhances production of protein encoded by nonsense mRNA. Nucleic Acids Res., 49:7665-7679, 2021 Cited by PubMed: 34157102DOI: 10.1093/nar/gkab532 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (4.1 Å) |
Structure validation
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