7NWH
Mammalian pre-termination 80S ribosome with eRF1 and eRF3 bound by Blasticidin S.
This is a non-PDB format compatible entry.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | 60S ribosomal protein L8 | polymer | 249 | 27129.8 | 1 | UniProt (Q3T0S6) Pfam (PF00181) Pfam (PF03947) | Oryctolagus cuniculus (Rabbit) | |
| 2 | B (C) | uL4 | polymer | 378 | 42825.6 | 1 | UniProt (G1SVW5) Pfam (PF00573) Pfam (PF14374) | Oryctolagus cuniculus (Rabbit) | |
| 3 | C (d) | eL31 | polymer | 108 | 12766.9 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 4 | D (DD) | 40S ribosomal protein S3 | polymer | 281 | 31146.6 | 1 | UniProt (G1TNM3) Pfam (PF07650) Pfam (PF00189) | Oryctolagus cuniculus (Rabbit) | |
| 5 | E (dd) | S29 | polymer | 56 | 6690.8 | 1 | Oryctolagus cuniculus | ||
| 6 | F (D) | 60S ribosomal protein L5 | polymer | 296 | 34350.6 | 1 | UniProt (G1SYJ6) UniProt (by SIFTS) (P19949) | Oryctolagus cuniculus (Rabbit) | |
| 7 | G (e) | Ribosomal protein L32 | polymer | 129 | 15153.2 | 1 | UniProt (G1U437) Pfam (PF01655) UniProt (by SIFTS) (G1TUN8) | Oryctolagus cuniculus (Rabbit) | |
| 8 | H (EE) | 40S ribosomal protein S4 | polymer | 263 | 29654.9 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 9 | I (ee) | 40S ribosomal protein S30 | polymer | 133 | 14498.9 | 1 | UniProt (G1T8A2) Pfam (PF00240) Pfam (PF04758) | Oryctolagus cuniculus (Rabbit) | |
| 10 | J (b) | eL29 | polymer | 226 | 24931.6 | 1 | UniProt (G1SGR6) Pfam (PF01779) | Oryctolagus cuniculus (Rabbit) | |
| 11 | K (E) | 60S ribosomal protein L6 | polymer | 291 | 33028.3 | 1 | UniProt (G1SKF7) Pfam (PF03868) Pfam (PF01159) | Oryctolagus cuniculus (Rabbit) | |
| 12 | L (f) | eL33 | polymer | 110 | 12580.8 | 1 | UniProt (G1SF08) Pfam (PF01247) | Oryctolagus cuniculus (Rabbit) | |
| 13 | M (FF) | Ribosomal protein S5 | polymer | 204 | 22913.5 | 1 | UniProt (G1TFM5) Pfam (PF00177) | Oryctolagus cuniculus (Rabbit) | |
| 14 | N (ff) | 40S ribosomal protein S27a | polymer | 68 | 7986.4 | 1 | UniProt (P62992) Pfam (PF01599) | Oryctolagus cuniculus (Rabbit) | |
| 15 | O (F) | uL30 | polymer | 249 | 29514.3 | 1 | UniProt (G1SV32) Pfam (PF08079) Pfam (PF00327) | Oryctolagus cuniculus (Rabbit) | |
| 16 | P (g) | 60S ribosomal protein L34 | polymer | 126 | 14210.1 | 1 | UniProt (G1U945) Pfam (PF01199) UniProt (by SIFTS) (G1TXG5) | Oryctolagus cuniculus (Rabbit) | |
| 17 | Q (BB) | 40S ribosomal protein S3a | polymer | 264 | 29942.0 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 18 | R (GG) | 40S ribosomal protein S6 | polymer | 263 | 30201.6 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 19 | S (gg) | Epididymis tissue sperm binding protein Li 3a | polymer | 314 | 34800.3 | 1 | UniProt (E9KL35) Pfam (PF00400) | Oryctolagus cuniculus (Rabbit) | |
| 20 | T (G) | L7a | polymer | 242 | 27611.8 | 1 | Oryctolagus cuniculus | ||
| 21 | U (h) | uL29 | polymer | 123 | 14566.6 | 1 | UniProt (G1SIT5) Pfam (PF00831) | Oryctolagus cuniculus (Rabbit) | |
| 22 | V (HH) | S7 | polymer | 191 | 21847.6 | 1 | Oryctolagus cuniculus | ||
| 23 | W (hh) | mRNA | polymer | 15 | 4753.9 | 1 | Oryctolagus cuniculus | ||
| 24 | X (bb) | 40S ribosomal protein S27 | polymer | 84 | 9480.2 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 25 | Y (H) | L9 | polymer | 190 | 21627.2 | 1 | UniProt (G1SWI6) Pfam (PF00347) | Oryctolagus cuniculus (Rabbit) | |
| 26 | Z (i) | 60S ribosomal protein L36 | polymer | 107 | 12317.8 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 27 | AA (II) | 40S ribosomal protein S8 | polymer | 208 | 24263.4 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 28 | BA (ii) | Eukaryotic peptide chain release factor subunit 1 | polymer | 437 | 49092.7 | 1 | UniProt (P62497) Pfam (PF03463) Pfam (PF03464) Pfam (PF03465) | Oryctolagus cuniculus (Rabbit) | Eukaryotic release factor 1,eRF1 |
| 29 | CA (I) | 60S ribosomal protein L10 | polymer | 214 | 24643.1 | 1 | UniProt (B7NZQ2) Pfam (PF00252) | Oryctolagus cuniculus (Rabbit) | Ribosomal protein L10 (Predicted) |
| 30 | DA (j) | Ribosomal protein L37 | polymer | 97 | 11111.0 | 1 | UniProt (U3KPD5) Pfam (PF01907) | Oryctolagus cuniculus (Rabbit) | |
| 31 | EA (JJ) | 40S ribosomal protein S9 | polymer | 194 | 22655.6 | 1 | UniProt (A0A1S3APZ1) Pfam (PF00163) Pfam (PF01479) | Oryctolagus cuniculus (Rabbit) | |
| 32 | FA (jj) | eRF3a | polymer | 428 | 48056.5 | 1 | Oryctolagus cuniculus | ||
| 33 | GA (J) | 60S ribosomal protein L11 | polymer | 176 | 20086.2 | 1 | UniProt (G1TUB8) Pfam (PF00281) Pfam (PF00673) | Oryctolagus cuniculus (Rabbit) | |
| 34 | HA (k) | L38 | polymer | 70 | 8238.9 | 1 | Oryctolagus cuniculus | ||
| 35 | IA (KK) | 40S ribosomal protein S10 | polymer | 151 | 17422.1 | 1 | UniProt (A0A2F0BDG8) | Oryctolagus cuniculus (Rabbit) | |
| 36 | JA (L) | 60S ribosomal protein L13 | polymer | 211 | 24331.7 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 37 | KA (l) | eL39 | polymer | 51 | 6455.8 | 1 | UniProt (G1TTN1) Pfam (PF00832) UniProt (by SIFTS) (G1SYU7) | Oryctolagus cuniculus (Rabbit) | |
| 38 | LA (LL) | 40S ribosomal protein S11 | polymer | 158 | 18513.8 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 39 | MA (M) | Ribosomal protein L14 | polymer | 218 | 23870.5 | 1 | UniProt (G1SZ12) Pfam (PF01929) | Oryctolagus cuniculus (Rabbit) | |
| 40 | NA (m) | 60S RIBOSOMAL PROTEIN EL40 | polymer | 128 | 14695.3 | 1 | Oryctolagus cuniculus | ||
| 41 | OA (MM) | 40S ribosomal protein S12 | polymer | 123 | 13709.1 | 1 | UniProt (G1SFR8) Pfam (PF01248) | Oryctolagus cuniculus (Rabbit) | |
| 42 | PA (N) | Ribosomal protein L15 | polymer | 204 | 24207.3 | 1 | UniProt (G1T0C1) Pfam (PF00827) | Oryctolagus cuniculus (Rabbit) | |
| 43 | QA (n) | 60s ribosomal protein l41 | polymer | 25 | 3473.5 | 1 | UniProt (A0A087WNH4) Pfam (PF05162) | Oryctolagus cuniculus (Rabbit) | eL41 |
| 44 | RA (NN) | ribosomal protein uS15 | polymer | 150 | 17188.3 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 45 | SA (O) | 60S RIBOSOMAL PROTEIN UL13 | polymer | 203 | 23533.3 | 1 | Oryctolagus cuniculus | ||
| 46 | TA (o) | eL42 | polymer | 142 | 16170.2 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 47 | UA (OO) | uS11 | polymer | 156 | 16916.5 | 1 | UniProt (G1T1F0) Pfam (PF00411) | Oryctolagus cuniculus (Rabbit) | |
| 48 | VA (P) | uL22 | polymer | 199 | 23056.2 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 49 | WA (p) | ribosomal protein eL43 | polymer | 109 | 12010.4 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 50 | XA (PP) | 40S ribosomal protein uS19 | polymer | 145 | 17049.2 | 1 | UniProt (G1U0Q2) Pfam (PF00203) | Oryctolagus cuniculus (Rabbit) | |
| 51 | YA (Q) | eL18 | polymer | 188 | 21699.7 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 52 | ZA (r) | eL28 | polymer | 137 | 15783.6 | 1 | UniProt (G1U7L1) Pfam (PF01778) | Oryctolagus cuniculus (Rabbit) | |
| 53 | AB (QQ) | Ribosomal protein S16 | polymer | 158 | 17716.9 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 54 | BB (R) | 60S ribosomal protein L19 | polymer | 196 | 23535.3 | 1 | UniProt (Q3T0W9) Pfam (PF01280) | Oryctolagus cuniculus (Rabbit) | |
| 55 | CB (s) | 60S acidic ribosomal protein P0 | polymer | 318 | 34380.5 | 1 | UniProt (G1SPK4) Pfam (PF00466) Pfam (PF17777) Pfam (PF00428) | Oryctolagus cuniculus (Rabbit) | |
| 56 | DB (RR) | 40S ribosomal protein S17 | polymer | 145 | 16782.6 | 1 | UniProt (S7Q348) Pfam (PF00833) | Oryctolagus cuniculus (Rabbit) | |
| 57 | EB (S) | 60S ribosomal protein L18a | polymer | 176 | 20827.6 | 1 | UniProt (A0A287APR1) Pfam (PF01775) | Oryctolagus cuniculus | |
| 58 | FB (t) | uL12 | polymer | 196 | 21426.8 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 59 | GB (SS) | 40S ribosomal protein uS13 | polymer | 152 | 17759.8 | 1 | UniProt (G1TPG3) Pfam (PF00416) | Oryctolagus cuniculus (Rabbit) | |
| 60 | HB (T) | eL21 | polymer | 160 | 18610.0 | 1 | UniProt (G1SHQ2) Pfam (PF01157) | Oryctolagus cuniculus (Rabbit) | |
| 61 | IB (TT) | eS19 | polymer | 145 | 16106.6 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 62 | JB (U) | L22 | polymer | 128 | 14799.0 | 1 | Oryctolagus cuniculus | ||
| 63 | KB (UU) | 40S ribosomal protein S20 | polymer | 118 | 13268.6 | 1 | Oryctolagus cuniculus | ||
| 64 | LB (V) | eL14 | polymer | 132 | 14103.6 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 65 | MB (VV) | 40S ribosomal protein S21 | polymer | 83 | 9124.4 | 1 | UniProt (Q32PB8) Pfam (PF01249) | Oryctolagus cuniculus | |
| 66 | NB (W) | 60S ribosomal protein L24-like protein | polymer | 134 | 15538.3 | 1 | UniProt (A0A061I3X8) Pfam (PF01246) | Oryctolagus cuniculus (Rabbit) | |
| 67 | OB (5) | 28S Ribosomal RNA | polymer | 3705 | 1199695.3 | 1 | Oryctolagus cuniculus | ||
| 68 | PB (WW) | Ribosomal protein S15a | polymer | 139 | 15778.6 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 69 | QB (X) | uL23 | polymer | 156 | 17768.2 | 1 | UniProt (G1SE76) Pfam (PF03939) Pfam (PF00276) | Oryctolagus cuniculus (Rabbit) | |
| 70 | RB (7) | 5S Ribosomal RNA | polymer | 120 | 38691.9 | 1 | GenBank (4CXE_4) | Oryctolagus cuniculus | |
| 71 | SB (XX) | 40S ribosomal protein uS12 | polymer | 142 | 15757.6 | 1 | UniProt (G1SZ47) Pfam (PF00164) | Oryctolagus cuniculus (Rabbit) | |
| 72 | TB (Y) | Ribosomal protein L26 | polymer | 134 | 15891.8 | 1 | UniProt (G1SQH0) Pfam (PF16906) Pfam (PF00467) | Oryctolagus cuniculus (Rabbit) | |
| 73 | UB (8) | 5.8S Ribosomal RNA | polymer | 151 | 48545.7 | 1 | Oryctolagus cuniculus | ||
| 74 | VB (YY) | 40S ribosomal protein S24 | polymer | 146 | 17007.1 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 75 | WB (Z) | 60S ribosomal protein L27 | polymer | 136 | 15835.8 | 1 | UniProt (G1TXF6) Pfam (PF00467) Pfam (PF01777) | Oryctolagus cuniculus (Rabbit) | |
| 76 | XB (9) | 18S Ribosomal RNA | polymer | 1779 | 573842.1 | 1 | Oryctolagus cuniculus | ||
| 77 | YB (ZZ) | 40S ribosomal protein S25 | polymer | 122 | 13450.8 | 1 | UniProt (G1TDB3) Pfam (PF03297) | Oryctolagus cuniculus (Rabbit) | |
| 78 | ZB (a) | 60S ribosomal protein L27a | polymer | 147 | 16489.4 | 1 | UniProt (G1SNY0) Pfam (PF00828) | Oryctolagus cuniculus (Rabbit) | |
| 79 | AC (AA) | 40S_SA_C domain-containing protein | polymer | 295 | 32958.0 | 1 | Oryctolagus cuniculus (Rabbit) | ||
| 80 | BC (aa) | 40S ribosomal protein S26 | polymer | 117 | 13147.6 | 1 | UniProt (T0M5X4) | Oryctolagus cuniculus (Rabbit) | |
| 81 | CC (B) | uL3 | polymer | 402 | 45976.8 | 1 | UniProt (G1TL06) Pfam (PF00297) | Oryctolagus cuniculus (Rabbit) | |
| 82 | DC (c) | eL30 | polymer | 115 | 12807.1 | 1 | UniProt (G1TDL2) Pfam (PF01248) | Oryctolagus cuniculus (Rabbit) | |
| 83 | EC (CC) | 40S ribosomal protein S2 | polymer | 259 | 27995.7 | 1 | Oryctolagus cuniculus (Bovine) | ||
| 84 | FC (cc) | 40S ribosomal protein S28 | polymer | 69 | 7836.0 | 1 | UniProt (G1TIB4) Pfam (PF01200) | Oryctolagus cuniculus (Rabbit) | |
| 85 | GC, HC, IC, KN, LC... (dd, ff, g, aa, j...) | ZINC ION | non-polymer | 65.4 | 8 | Chemie (ZN) | |||
| 86 | AD, AE, AF, AG, AH... (5, 9, 7, 8, hh...) | MAGNESIUM ION | non-polymer | 24.3 | 281 | Chemie (MG) | |||
| 87 | NC (jj) | PHOSPHOMETHYLPHOSPHONIC ACID GUANYLATE ESTER | non-polymer | 521.2 | 1 | Chemie (GCP) | |||
| 88 | QD (5) | BLASTICIDIN S | non-polymer | 422.4 | 1 | Chemie (BLS) |
Sequence modifications
cc: 1 - 69 (UniProt: G1TIB4)
| PDB | External Database | Details |
|---|---|---|
| His 5 | Arg 5 | conflict |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 84 |
| Total formula weight | 3468220.6 | |
| Non-Polymers* | Number of molecules | 291 |
| Total formula weight | 8296.6 | |
| All* | Total formula weight | 3476517.2 |
