7AZY
Context-specific inhibition of eukaryotic translation by macrolide antibiotics
This is a non-PDB format compatible entry.
Summary for 7AZY
Entry DOI | 10.2210/pdb7azy/pdb |
EMDB information | 11951 |
Descriptor | 60S ribosomal protein L8-A, 60S ribosomal protein L13-A, 60S ribosomal protein L26-A, ... (44 entities in total) |
Functional Keywords | context-specific inhibition, macrolide antibiotic, ribosome, telithromycin |
Biological source | Saccharomyces cerevisiae (strain ATCC 204508 / S288c) (Baker's yeast) More |
Total number of polymer chains | 42 |
Total formula weight | 1916774.59 |
Authors | Koller, T.O.,Wilson, D.N. (deposition date: 2020-11-17, release date: 2021-05-19, Last modification date: 2024-07-10) |
Primary citation | Svetlov, M.S.,Koller, T.O.,Meydan, S.,Shankar, V.,Klepacki, D.,Polacek, N.,Guydosh, N.R.,Vazquez-Laslop, N.,Wilson, D.N.,Mankin, A.S. Context-specific action of macrolide antibiotics on the eukaryotic ribosome. Nat Commun, 12:2803-2803, 2021 Cited by PubMed: 33990576DOI: 10.1038/s41467-021-23068-1 PDB entries with the same primary citation |
Experimental method | ELECTRON MICROSCOPY (2.877 Å) |
Structure validation
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